21,770 real negative results, null findings, and replication failures. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Safiejko K, Juchimiuk M, Pierko J et al. · 2026 · Cancers
Background: Liquid biopsy using circulating tumor DNA (ctDNA) is rapidly reshaping gastrointestinal (GI) oncology. The highest-impact applications are molecular residual disease (mRD) detection after curative-intent therapy and early…
View details →Bruce ATI, Faria MGBF, Andrade RLP et al. · 2026 · Revista brasileira de epidemiologia = Brazilian journal of epidemiology
Objective To analyze the factors associated with the frequency of false negative results for the RMT-TB test for the diagnosis of pulmonary tuberculosis in the state of São Paulo. Methods Cross-sectional study using pulmonary tuberculosis…
View details →Ali H, Kumurya A, Ajagbe J et al. · 2026 · Preprint
ABSTRACT Importance Molecular confirmation of Listeria monocytogenes typically employs a multiplex PCR method that targets both genus-specific prs and species-specific hlyA genes. This study assessed the specificity of this assay within…
View details →Marin J · 2025 · Preprint
When retrieval-augmented generation (RAG) systems hallucinate, what geometric trace does this leave in embedding space? We introduce the Semantic Grounding Index (SGI), defined as the ratio of angular distances from the response to the…
View details →Cengiz SK, Demirer E, Baysal T et al. · 2026 · Annals of Saudi medicine
Background Managing small Lung-RADS 4 pulmonary nodules is clinically challenging. While CT-guided TTFNAB is standard, its efficacy and safety for lesions ≤2 cm require further evaluation to optimize outcomes and reduce unnecessary…
View details →Seyama S, Uwamino Y, Yoshihara K et al. · 2026 · Diagnostic microbiology and infectious disease
Accurate subspecies identification and determination of macrolide resistance status are crucial for the treatment of Mycobacterium abscessus complex (MABC) infections. In recent years, a kit that uses DNA chromatography to differentiate…
View details →Knasmüller S, Nersesyan A, Mišík M et al. · 2026 · Mutagenesis
We describe the impact of lifestyle related factors on the formation of micronuclei (MN) in buccal cells. It is known that consumption of alcohol and of other drugs including tobacco and other plants cause damage of the genetic material…
View details →Vardanega MJ, Longo T, Aceino A et al. · 2026 · Journal of veterinary internal medicine
Vulvovaginal squamous cell carcinoma (SCC) is an uncommon neoplasm in dogs. An 11-year-old female spayed German Shepherd dog presented with a history of excessive peri-vulvar grooming and a 3 cm × 3 cm irregular mass involving the vagina…
View details →Goubeau L, Curis E, Delavenne X et al. · 2026 · Blood advances
Phase 3 trials evaluating inhibitors of coagulation factor (F) XI and/or its activated form (FXIa) as novel anticoagulant drugs are ongoing. These agents include parenteral monoclonal antibody (abelacimab) and oral small molecules…
View details →Limbu N, Lamsal RR, Shrestha A · 2025 · Preprint
Abstract Citrus Decline, a complex and devastating disorder caused by various biotic and abiotic factors has emerged as a significant challenge for citrus cultivation in Nepal. This study on “Prevalence and severity of citrus decline and…
View details →Ünal F, Gülhan B, Yüksek SK et al. · 2026 · Diagnostic microbiology and infectious disease
Background This study aimed to evaluate the diagnostic performance of serum galactomannan for invasive fungal infections in children with hematologic malignancies and to assess the impact of mold-active antifungal prophylaxis on test…
View details →Schouten CS, Guarda V, Stadler TM et al. · 2026 · Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Background Human papillomavirus (HPV)-16 is the most commonly found HPV-type in HPV-induced oropharyngeal squamous cell carcinomas (OPSCC). The serological response to HPV oncoproteins could be a way to detect HPV-driven OPSCC early. A…
View details →Khan A, Jaynes A, Ali F et al. · 2025 · Journal of translational gastroenterology
Background and objectives Guaiac fecal occult blood test (gFOBT) is often used to evaluate evidence of food protein-induced allergic proctocolitis (FPIAP) in children in primary care and gastroenterology settings; however, it has not been…
View details →Yin J, Wang Q, Lan T et al. · 2026 · Frontiers in pediatrics
Background Copy number variants of uncertain significance (VUS-CNVs) pose significant challenges in prenatal counseling for congenital heart malformations (CHMs). Their clinical relevance remains poorly defined, particularly in the absence…
View details →Kazanskii M, Golikova M, Kasianov A et al. · 2025 · Preprint
We investigated the possibility of estimating the age of ancient biological samples directly from their DNA damage profiles using supervised machine learning. Traditional dating methods such as radiocarbon dating, dendrochronology rely on…
View details →Iwata K, Mori N, Ogasawara K · 2025 · Cureus
Introduction Noninvasive methods for assessing liver fibrosis are increasingly important for early detection of advanced liver fibrosis (ALF), particularly in patients with metabolic dysfunction-associated steatotic liver disease (MASLD).…
View details →Zych-Krekora K, Sylwestrzak O, Krekora M · 2026 · Journal of clinical medicine
Background/Objectives : Maternal rectovaginal carriage of Group B Streptococcus (GBS, Streptococcus agalactiae ) is a major risk factor for vertical transmission and early-onset neonatal infection. Intrapartum antibiotic prophylaxis…
View details →Galván CA, Durán R, Larco JI et al. · 2026 · Immunity, inflammation and disease
Background Accurate identification of respiratory allergen sensitization is essential for managing asthma and allergic rhinitis (AR). While Skin Prick Test (SPT) and ImmunoCAP are standard diagnostic tools, exploratory comparative data for…
View details →Nakai Y, Onishi K, Asakawa I et al. · 2026 · The Prostate
Background Long-term clinical data evaluating oncological outcomes and patient-reported quality of life (QOL) after combining celecoxib with radiotherapy are lacking. Therefore, we aimed to assess oncological outcomes and QOL with extended…
View details →Oshiro Y, Kawashima A, Akashi M et al. · 2026 · Tropical medicine and health
Background Giardiasis and cryptosporidiosis are often misdiagnosed by stool ova and parasite test (classical O&P). Multiplex PCR and rapid antigen immunochromatography (rapid-IC) could offer high diagnostic accuracy; however, their cost…
View details →Espigares LF, Panadero AF, Sánchez MD et al. · 2026 · Multiple sclerosis and related disorders
Objective Accurate anti-JC virus (JCV) antibody testing is essential for progressive multifocal leukoencephalopathy (PML) risk stratification in natalizumab-treated patients. This study assessed evaluated inter-assay concordance between…
View details →Grynkiewicz M, Buffi NM, Fasulo V et al. · 2025 · Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques
Introduction Research results suggest that high-resolution ultrasonography (microUS) can be used to estimate the risk of prostate cancer (PCa) and identify suspicious areas, enabling precise biopsy during examination. Aim The aim of the…
View details →Amate A, Lieberman M · 2025 · Preprint
Abstract Medetomidine has recently emerged in the illicit drug supply in the United States, and lateral flow immunoassay test strips are an inexpensive and easy-to-use field screening option for detecting this highly potent sedative.…
View details →van Rooij JLM, Wessels PH, Niers JM et al. · 2026 · The Lancet. Haematology
Background Primary CNS lymphoma is typically diagnosed by brain biopsy, a procedure with risks and diagnostic delay. Emerging cerebrospinal fluid (CSF) biomarkers, including the myeloid differentiation primary response 88 (MYD88) L265P…
View details →Newman A, Hansel S, Gerrard G et al. · 2026 · Cancers
Background Surveillance of non-muscle-invasive bladder cancer (NMIBC) relies on cystoscopy and urine cytology, both of which have well-recognised limitations. Molecular urine assays have been developed to reduce the burden of invasive…
View details →Mints G, Bai J, Evans A · 2025 · American journal of cardiovascular disease
This is letter to the editor: we point to a statistical error in a recent article published in the journal by Movahed MR, Soltani Moghadam A. A normal and particularly small ( , which may have resulted in a biased conclusion.
View details →Eldeeb MEA, Mostafa MA, Nagiub TA et al. · 2025 · BMC cardiovascular disorders
Purpose Prior studies have assessed in-stent diameter restenosis (ISDR) in coronary arteries using 64-slice multidetector computed tomography coronary angiography (MDCT-CA) compared to invasive coronary angiography (ICA), which is the gold…
View details →Follansbee CW, Landstrom AP, Aziz PF · 2025 · Cardiac electrophysiology clinics
Congenital long QT syndrome is the most common inherited arrhythmia syndrome and is characterized by prolongation of the QT interval in the absence of structural heart disease or external factors. Disease will often manifest during…
View details →Trinh AT, McMurray JC, Pittman LM et al. · 2025 · JACC. Case reports
Background IgE-mediated anaphylaxis to iodinated contrast media (ICM) is rare but potentially life threatening. Unlike non-IgE-mediated reactions, cases are often resistant to corticosteroid and antihistamine premedication. Case summary A…
View details →Kim DH, Chun MK, Lim SY et al. · 2026 · Pediatric emergency care
Objectives This retrospective observational study evaluated the diagnostic efficiency of routine magnetic resonance imaging (MRI) in pediatric patients with facial palsy (FP) in the emergency department (ED). Methods Pediatric patients…
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