Negative / Null Result ReportOpen accessNursing
Charles F. Manful, Eric Fordjour, Dasinaa Subramaniam et al. · 2025 · International Journal of Molecular Sciences
Reactive molecules, including oxygen and nitrogen species, serve dual roles in human physiology. While they function as essential signaling molecules under normal physiological conditions, they contribute to cellular dysfunction and damage when produced in excess by normal metabolism or in response to stressors. Oxidative/nitrosative stress is a pathological state, resulting from the overproduction of reactive species exceeding the antioxidant capacity of the body, which is implicated in several chronic human diseases. Antioxidant therapies aimed at restoring redox balance and preventing oxida
View details →Negative / Null Result ReportOpen accessComputer Science
Abu Saleh Musa Miah, Jungpil Shin, Md. Al Mehedi Hasan et al. · 2022 · Applied Sciences
Sign language recognition is one of the most challenging applications in machine learning and human-computer interaction. Many researchers have developed classification models for different sign languages such as English, Arabic, Japanese, and Bengali; however, no significant research has been done on the general-shape performance for different datasets. Most research work has achieved satisfactory performance with a small dataset. These models may fail to replicate the same performance for evaluating different and larger datasets. In this context, this paper proposes a novel method for recogn
View details →Negative / Null Result ReportOpen accessMedicine
Britt Clynick, Tamera J. Corte, Helen E. Jo et al. · 2021 · European Respiratory Journal
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease in which circulatory biomarkers have the potential for guiding management in clinical practice. We assessed the prognostic role of serum biomarkers in three…
View details →Negative / Null Result ReportOpen accessEngineering
Nathan Hendricks, Jeffrey M. Peterson, Hendricks, Nathan P. et al. · 2012 · AgEcon Search (University of Minnesota, USA)
Irrigation water demand is estimated using field-level panel data from Kansas over 16 years. The cost of pumping varies over time due to changes in energy prices and across space due to differences in the depth to water. Exploiting this…
View details →Negative / Null Result ReportOpen accessDentistry
DE McLean, EJ Meyers, VL Guillory et al. · 2015 · Operative Dentistry
PURPOSE: Universal bonding agents have been introduced for use as self-etch or etch-and-rinse adhesives depending on the dental substrate and clinician's preference. The purpose of this study was to evaluate the shear bond strength (SBS)…
View details →Negative / Null Result ReportOpen accessPhysics and Astronomy
Antoine Boutet, Hyoungshick Kim, Eiko Yoneki · 2021 · Proceedings of the International AAAI Conference on Web and Social Media
Nowadays, the use of social media such as Twitter is necessary to monitor trends of people on political issues. As a case study, we collected the main stream of Twitter related to the 2010 UK general election during the associated period.…
View details →Negative / Null Result ReportOpen accessEnvironmental Science
Michael J. Ford, M. Bradley Hanson, Jennifer A. Hempelmann et al. · 2011 · Journal of Heredity
We used data from 78 individuals at 26 microsatellite loci to infer parental and sibling relationships within a community of fish-eating ("resident") eastern North Pacific killer whales (Orcinus orca). Paternity analysis involving 15…
View details →Negative / Null Result ReportNeuroscience
Lin Du, Ling Shan, Bing Wang et al. · 2015 · Journal of Child and Adolescent Psychopharmacology
OBJECTIVE: The purpose of this study was to investigate the therapeutic effects of combined bumetanide and applied behavior analysis (ABA) treatment in children with autism. METHODS: Sixty children diagnosed with autism according to the…
View details →Negative / Null Result ReportMedicine
James Holland, David Langton, Munawar Hashmi · 2012 · Journal of Bone and Joint Surgery - British Volume
We present the clinical results and survivorship of consecutive 100 Birmingham Hip Resurfacings in 90 patients at a minimum follow-up of ten years. All procedures were carried out by an independent surgeon who commenced a prospective study…
View details →Negative / Null Result ReportOpen accessNursing
James J. DiNicolantonio, James H. O’Keefe · 2018 · Open Heart
The intake of omega-6 vegetable oils, particularly soybean oil, began to increase in the USA starting in the early 1900s at a time when the consumption of butter and lard was on the decline.1 This caused a more than two-fold increase in…
View details →Negative / Null Result ReportEngineering
Hengtao Wang, Hui Chen, Weicheng Xie et al. · 2021 · Advanced Functional Materials
Abstract The design of polymer acceptors plays an essential role in the performance of all‐polymer solar cells. Recently, the strategy of polymerized small molecules has achieved great success, but most polymers are synthesized from the…
View details →Negative / Null Result ReportMedicine
Jody Tversky, Andrew P. Lane, Antoine Azar · 2021 · Clinical & Experimental Allergy
BACKGROUND: Chronic rhinosinusitis with nasal polyps (CRSwNP) can be a severe and debilitating disease associated with significant morbidity, loss of smell, sinus pressure and asthma exacerbations. Eosinophils play a role in the majority…
View details →Negative / Null Result ReportOpen accessMedicine
Balaji Rangarathnam, Gary H. McCullough, Hylan Pickett et al. · 2015 · American Journal of Speech-Language Pathology
PURPOSE: The purpose of this study was to investigate the utility of telepractice for delivering flow phonation exercises to persons with primary muscle tension dysphonia (MTD). METHOD: Fourteen participants with a diagnosis of primary MTD…
View details →Negative / Null Result ReportOpen accessMedicine
Christopher W. Lewis, Jamiluddin Qazi, Daniel S. Hippe et al. · 2019 · Cancer Medicine
Approximately one-third of Merkel cell carcinoma (MCC) patients eventually develop distant metastatic disease. Little is known about whether the location of the primary lesion is predictive of initial distant metastatic site, or if survival likelihood differs depending on the metastatic site. Such data could inform imaging/surveillance practices and improve prognostic accuracy. Multivariate and competing-risk analyses were performed on a cohort of 215 MCC patients with distant metastases, 31% of whom had two or more initial sites of distant metastasis. At time of initial distant metastasis in
View details →Negative / Null Result ReportOpen accessMedicine
Hiroto Inaba, Yinmei Zhou, Oussama Abla et al. · 2015 · Blood
Comprehensive clinical studies of patients with acute megakaryoblastic leukemia (AMKL) are lacking. We performed an international retrospective study on 490 patients (age ≤18 years) with non-Down syndrome de novo AMKL diagnosed from 1989…
View details →Negative / Null Result ReportOpen accessMedicine
Felice Nava, Irene Tramacere, Veronica Andrea Fittipaldo et al. · 2014 · Neuro-Oncology
BACKGROUND: Prospective follow-up studies of large cohorts of patients with glioblastoma (GBM) are needed to assess the effectiveness of conventional treatments in clinical practice. We report GBM survival data from the Brain Cancer…
View details →Negative / Null Result ReportMedicine
Scott A. Asher, Hilliary N. White, Alexandra E. Kejner et al. · 2013 · Otolaryngology
OBJECTIVE: An increasing number of head and neck surgeons have begun using transoral robotic-assisted surgery. Our objective was to examine the postoperative bleeding complications we have encountered to determine risk factors and to…
View details →Negative / Null Result Report
Elizabeth Selvin · 2016 · Diabetes Care
Studies that have compared HbA1c levels by race have consistently demonstrated higher HbA1c levels in African Americans than in whites. These racial differences in HbA1c have not been explained by measured differences in glycemia,…
View details →Negative / Null Result ReportOpen accessMedicine
Katherine D. LaClair, Kebreten F. Manaye, Dexter L. Lee et al. · 2013 · Molecular Neurodegeneration
BACKGROUND: Though the precise cause(s) of Alzheimer's disease (AD) remain unknown, there is strong evidence that decreased clearance of β-amyloid (Aβ) from the brain can contribute to the disease. Therapeutic strategies to promote natural Aβ clearance mechanisms, such as the protein apolipoprotein-E (APOE), hold promise for the treatment of AD. The amount of APOE in the brain is regulated by nuclear receptors including retinoid X receptors (RXRs). Drugs that activate RXRs, including bexarotene, can increase APOE and ABCA1 production, and have been shown to decrease the Aβ burden and improve c
View details →Failed Experiment ReportOpen accessMedicine
Lauren A. Wise, Edward Ruiz-Narváez, Julie R. Palmer et al. · 2012 · American Journal of Epidemiology
Rates of uterine leiomyomata (UL) are 2-3 times higher in African Americans than in European Americans. It is unclear whether inherited factors explain the ethnic disparity. To investigate the presence of risk alleles for UL that are…
View details →Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance
Jean‐Frédéric Morin, Sikina Jinnah · 2018 · Environmental Politics
The regulatory contribution that preferential trade agreements (PTAs) make to global climate governance is assessed through an analysis of climate-related provisions found in 688 PTAs signed between 1947 and 2016. Provisions are analyzed…
View details →Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Nathan Pankratz, Alexandra Dumitriu, Kurt N. Hetrick et al. · 2011 · PLoS ONE
Copy number variants (CNVs) are known to cause Mendelian forms of Parkinson disease (PD), most notably in SNCA and PARK2. PARK2 has a recessive mode of inheritance; however, recent evidence demonstrates that a single CNV in PARK2 (but not a single missense mutation) may increase risk for PD. We recently performed a genome-wide association study for PD that excluded individuals known to have either a LRRK2 mutation or two PARK2 mutations. Data from the Illumina370Duo arrays were re-clustered using only white individuals with high quality intensity data, and CNV calls were made using two algorit
View details →Negative / Null Result ReportEnvironmental Science
Markus Brinkmann, Sibylle Maletz, Martin Krauß et al. · 2014 · Environmental Science & Technology
Heterocyclic aromatic hydrocarbons (hetero-PAHs) are increasingly studied at contaminated sites; especially at former industrial facilities where coal tar-oil was handled, e.g., wood treatment plants, high concentrations of hetero-PAHs are…
View details →Negative / Null Result ReportOpen accessSocial Sciences
Abd. Syakur, Tri Achmad Budi Susilo, Wike Wike et al. · 2020 · Budapest International Research and Critics Institute (BIRCI-Journal) Humanities and Social Sciences
This reserach was focused and related to effect of sustainability communication, bureaucracy structure and public support which have significant effect toward policy implementation performance and to execute Three Dharma (education, research and comunity service) in higher education. Communication, resources, bureaucracy structure and public support has its influence against disposition. In bureaucracy structure, public support has significant effect toward its main resources which is lecturer or its teaching staff. This study aimed to analyze the effect of communication and organizational cul
View details →Negative / Null Result ReportPsychology
Angela K.‐Y. Leung, Shyhnan Liou, Ella Miron‐Spektor et al. · 2017 · Journal of Personality and Social Psychology
Thriving in increasingly complex and ambiguous environments requires creativity and the capability to reconcile conflicting demands. Recent evidence with Western samples has suggested that paradoxical frames, or mental templates that…
View details →Negative / Null Result ReportOpen accessNeuroscience
Tadeusz W. Kononowicz, Hedderik van Rijn · 2011 · Frontiers in Integrative Neuroscience
Numerous studies have shown that contingent negative variation (CNV) measured at fronto-central and parietal-central areas is closely related to interval timing. However, the exact nature of the relation between CNV and the underlying timing mechanisms is still a topic of discussion. On the one hand, it has been proposed that the CNV measured at supplementary motor area (SMA) is a direct reflection of the unfolding of time since a perceived onset, whereas other work has suggested that the increased amplitude reflects decision processes involved in interval timing. Strong evidence for the first
View details →Negative / Null Result ReportOpen accessComputer Science
Manamba Epaphra, Ales H. Mwakalasya · 2017 · Modern Economy
This paper analyzes the effect of foreign direct investment (FDI) on agricultural sector in Tanzania. The paper also examines the declining contribution of agriculture to real GDP growth despite the fact that the sector employs more than 70 percent of the total labour force. Annual time series data spanning from 1990 to 2015 are used to test the significance of the relationship between FDI inflow and agriculture value added-to-GDP ratio on one hand and FDI inflows and economic growth on the other hand. Also, the relationship between agriculture value added and economic growth rate is empirical
View details →Negative / Null Result ReportSocial Sciences
Joseph Raffiee, Heejung Byun · 2019 · Academy of Management Journal
This study revisits the portability of performance paradox—the common finding that external hires fail to replicate prior performance after switching firms—by examining how the nature of an employee’s human capital and social capital…
View details →Negative / Null Result ReportOpen accessPsychology
Alecia C. Vogel, Steven E. Petersen, Bradley L. Schlaggar · 2012 · Cerebral Cortex
Regions in left occipitotemporal (OT) cortex, including the putative visual word form area, are among the most commonly activated in imaging studies of single-word reading. It remains unclear whether this part of the brain is more…
View details →Negative / Null Result ReportOpen accessPhysics and Astronomy
L. Easy, F. Militello, John Omotani et al. · 2014 · Physics of Plasmas
This paper presents simulations of isolated 3D filaments in a slab geometry obtained using a newly developed 3D reduced fluid code, written using the BOUT++ framework. First, systematic scans were performed to investigate how the dynamics…
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