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Browse the failure-mode index

21,742 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Endoscopic three-layer graft myringoplasty without tympanomeatal flap elevation for repairing subtotal and total perforations.

Lou Z, Yang H · 2026 · European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

OBJECTIVE: The objective of this study was to evaluate the graft success rate, hearing outcomes, and complications associated with three-layer graft myringoplasty for repairing subtotal and total perforations. MATERIALS AND METHODS:…

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Negative / Null Result ReportMedicine

Outcomes from a structured conflict management programme implemented at three paediatric healthcare sites: a mixed-methods evaluation.

Phillipson J, Menson E, Barclay S et al. · 2026 · Archives of disease in childhood

Objective Evaluation of the Medical Mediation Foundation's Conflict Management Programme (CMP)-a structured process for managing conflict. Design Mixed-methods evaluation using Kirkpatrick's framework, a four-level model for evaluating…

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Negative / Null Result ReportMedicine

Daily-life posttraumatic stress symptoms, posttraumatic cognitions, and affect following the processing of positive memories technique: An open-label case-control daily diary study.

Greene T, Dicker-Oren SD, Sznitman SR et al. · 2026 · Journal of traumatic stress

The processing of positive memories technique (PPMT) is a promising new treatment for posttraumatic stress disorder (PTSD) involving the detailed narration and processing of specific positive autobiographical memories. This study used an…

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Negative / Null Result ReportOpen accessMedicine

The Effect of Ocrelizumab on Anti-JC Virus Antibody Index.

Virupakshaiah A, Gill AJ, Schoeps VA et al. · 2026 · Brain and behavior

Purpose/introduction The anti-JC virus (JCV) antibody index is used to stratify the risk of progressive multifocal leukoencephalopathy (PML) in multiple sclerosis (MS), particularly with natalizumab therapy. B-cell-depleting therapies may…

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Negative / Null Result ReportMedicine

Impact of low-flow desflurane versus sevoflurane anesthesia on thiol-disulfide homeostasis in adults undergoing elective thyroidectomy: a randomized controlled trial.

Sen E, Aytekin A · 2026 · Revista da Associacao Medica Brasileira (1992)

Objective Thiol-disulfide homeostasis is a marker of oxidative stress. The aim of the study was to compare the effects of low-flow desflurane and sevoflurane anesthesia on perioperative changes in thiol-disulfide balance in patients…

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Negative / Null Result ReportMedicine

Long-term outcomes of patients with moderate-severe pediatric systemic lupus erythematosus treated with combination rituximab and cyclophosphamide therapy: A single center cohort experience and review of literature.

Achar A, Houser P, Cherian J et al. · 2026 · Lupus

ObjectiveTo determine the long-term outcomes of patients with moderate-severe pediatric systemic lupus erythematosus (pSLE) treated with systematic administration of combination rituximab (RTX) and cyclophosphamide (CYC) at our…

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Negative / Null Result Report

Epidemiology of Microbial Keratitis on Uganda: A 7-year update

Arunga S, Ebong A, Orishaba F et al. · 2026 · Preprint

Purpose To provide the latest update on the epidemiology of microbial keratitis in Uganda. Methods We prospectively recruited patients presenting with microbial keratitis (MK) at three eye units in Uganda between November 2023 and June…

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Abandoned HypothesisOpen accessMedicine

Presbyvestibulopathy: an uncommon cause of dizziness in the elderly.

Chang TP, Kuo YH, Bery AK · 2026 · Frontiers in neurology

Background Dizziness is common in older adults, and often presents a diagnostic challenge. Vestibular function declines with age, but the prevalence and diagnostic explanatory value of mild vestibular loss in isolation (i.e., the clinical…

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Negative / Null Result ReportMedicine

Evaluating a specialty-specific objective structured clinical examination and workplace-based assessment curriculum for radiation oncology postgraduate training: a prospective educational intervention study.

Ma CY, Chen J, Fu Y et al. · 2026 · BMC medical education

Background Competence in radiation oncology is still commonly expected to emerge through apprenticeship, although essential tasks such as target delineation, treatment-plan review, and multidisciplinary reasoning are not reliably sampled…

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Negative / Null Result ReportOpen accessMedicine

Effects of Premolar Extraction on the Dimensions of the Airway Through Cephalometric Appraisal: A Retrospective Study.

Mehraj F, Bhat MA, Mangulkar A et al. · 2025 · Journal of pharmacy & bioallied sciences

Introduction In recent years, there has been a great deal of interest in research because of the changes that the extraction of premolars has caused to the structures surrounding of the upper airway. This is because it's thought that these…

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