Aortic asprosin overexpression does not ameliorate disease pathophysiology in a murine model of Marfan syndrome.
Shetty PMV; Matzen A; Hille S; Michalewski S; Witthaus H; Noormalal M; Marcous F; Morcos Y · 2026 · Scientific reports
WASTE classifies this as Failed Experiment Report · AI classification, approximate
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Abstract (excerpt)
Marfan syndrome (MFS) is a connective tissue disorder caused by FBN1 mutations, characterised by aortic aneurysms leading to life-threatening dissections. Asprosin is the C-terminal propeptide of fibrillin-1 that was shown to function as a…
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Metadata source: Europe PMC · DOI 10.1038/s41598-026-59187-2