Negative / Null Result ReportMedicine
Piri K, Gholamzadeh Jofreh M, Haghighizadeh MH et al. · 2026 · BMC psychology
Introduction Fear of childbirth (FOC) is a significant factor contributing to requests for elective cesarean sections. This study aimed to compare the effectiveness of internet-based cognitive behavioral therapy (ICBT) versus in-person…
View details →Negative / Null Result ReportMedicine
Dijksterhuis J, Hurmuz MZM, van Dartel D et al. · 2026 · European geriatric medicine
Purpose Older hip fracture patients are often frail, complicating their recovery trajectories. Insight into patients' resilience may help in getting more understanding of their predicted recovery and adjusting their treatment plan…
View details →Negative / Null Result ReportOpen accessMedicine
Shanmugasundaram D, Wang RA · 2026 · Journal of toxicology
Objective Zylaria comprises a blend of botanical components, including Xylaria Nigripes (mycelium), Cuscuta Chinensis (seed) and Panax Notoginseng (root). This study aimed to evaluate the potential toxicity of Zylaria when administered…
View details →Negative / Null Result ReportOpen accessMedicine
Motomura T, Higashi M, Hattori A et al. · 2026 · Internal medicine (Tokyo, Japan)
Objective Hyperuricemia is associated with cardiovascular disease and chronic kidney disease (CKD). Dotinurad is a new uricosuric drug that has not been evaluated in clinical trials in patients with advanced CKD (CKD G3b-G5). This study…
View details →Negative / Null Result ReportMedicine
Pedersen TA, Mori Y, Botteri E et al. · 2026 · Endoscopy
Background The effect of computer-aided detection (CADe) on performance of endoscopists with different experience levels is not well understood. This study assessed whether CADe use promotes learning or deskilling. Methods We performed a…
View details →Negative / Null Result ReportMedicine
Hoskens S, Bamps K, Herteleer M · 2026 · European journal of orthopaedic surgery & traumatology : orthopedie traumatologie
Objectives The percutaneous placement of iliosacral (IS) and transsacral (TS) screws has become a standard practice for the treatment of pelvic fractures. Due to the complex sacral anatomy, accurate screw placement is essential to avoid…
View details →Negative / Null Result Report
Sacconi R, Saladino S, Forte P et al. · 2026 · Preprint
Abstract There is a lack of knowledge about the effect of smoking activity on the anatomy and functionality of retinal vessels. The aim of this low-risk, single-center, case-control, interventional clinical trial (ClinicalTrials.gov ID…
View details →Negative / Null Result Report
Cagini C, Messina M, Fiore T et al. · 2026 · Preprint
Abstract Purpose This study investigates the efficacy of a liposomal ophthalmic solution containing cross-linked hyaluronic acid, trehalose, and stearylamine in reducing the occurrence of dry eye-like signs and symptoms in patients…
View details →Negative / Null Result ReportOpen accessMedicine
Muñoz-Vendrell A, Arroyo-Pereiro P, León I et al. · 2026 · Journal of neurology
Background Subcutaneous natalizumab offers greater convenience than intravenous administration, but pharmacokinetic differences have raised concerns about potential subclinical disease activity. Serum neurofilament light chain (sNfL) and…
View details →Failed Experiment ReportMedicine
Boegl M, Kasper I, Dewailly D et al. · 2026 · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
Objective Up to 50% of women with functional hypothalamic amenorrhea (FHA) exhibit polycystic ovarian morphology (PCOM) on ultrasound. We aimed to compare the hormonal response to ovulation induction with pulsatile GnRH therapy in FHA…
View details →Negative / Null Result ReportMedicine
Zhao L, Zeng C, Jia X et al. · 2026 · Medicine
Breast cancer (BC) has the highest cancer incidence and mortality in women worldwide, and the relationship between serum enzymes and BC has been inconsistent in previous observational studies. In this paper, 2-sample Mendelian…
View details →Negative / Null Result ReportMedicine
Al-Mohana RAAM, Jianping H, Alhammadi MS et al. · 2026 · Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
Objective To elucidate the pattern and extent of long-term condylar adaptation within the temporomandibular joint (TMJ) following mandibular setback by bilateral sagittal split osteotomy (BSSO) in patients with mandibular prognathism, with…
View details →Negative / Null Result ReportMedicine
Kubota H, Makino Y, Yoshida M et al. · 2026 · International journal of legal medicine
Background It is important to understand post-mortem changes in post-mortem computed tomography (PMCT) image interpretation. Only a few studies have focused on the eyeballs. This study aimed to clarify the changes in eyeball findings on…
View details →Negative / Null Result ReportOpen accessMedicine
Lu Y, Shu L, Liu C et al. · 2026 · Frontiers in cardiovascular medicine
Background Ethanol infusion of the vein of Marshall (EIVOM) has emerged as a promising adjunct to pulmonary vein isolation (PVI) for atrial fibrillation (AF). Methods Patients undergoing catheter ablation for persistent AF (>3 months) were…
View details →Negative / Null Result ReportMedicine
Kocaman Y, Yanmaz LE · 2026 · Veterinary ophthalmology
Purpose This study aimed to evaluate the effects of ivermectin administration on aqueous tear production and ocular surface health in dogs and to investigate its potential association with quantitative keratoconjunctivitis sicca (KCS).…
View details →Negative / Null Result ReportMedicine
Lin YJ, Chen QY, Zhao SY et al. · 2026 · Retina (Philadelphia, Pa.)
Purpose This study investigated the clinical characteristics and prognosis of rhegmatogenous retinal detachment (RRD) in patients with implantable collamer lens (ICL). Methods A retrospective review was conducted of medical records from…
View details →Negative / Null Result ReportMedicine
Treanor M, Zbozinek TD, Rosenberg BM et al. · 2025 · Journal of consulting and clinical psychology
Objective To investigate the role of extinction learning and habituation by comparing inhibitory retrieval to habituation-focused exposure for social anxiety and panic disorder. Method In this assessor-blinded, parallel-group, two-arm…
View details →Negative / Null Result ReportMedicine
Demirel N, Yildiz B, Demir M · 2026 · Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
Objective To evaluate the safety and efficacy of CDK4/6 inhibitors in combination with hormone therapy, and to investigate potential predictive markers of treatment in metastatic breast cancer (MBC). Study design An observational study.…
View details →Negative / Null Result Report
K S, V KC, S AK et al. · 2026 · Preprint
Abstract Background: Vernal keratoconjunctivitis (VKC) is a chronic, recurrent allergic ocular disorder predominantly affecting children and adolescents. Vitamin D deficiency has been implicated in allergic conditions; however, its…
View details →Negative / Null Result ReportMedicine
Hashemi TM, Khami MR, Razeghi S et al. · 2026 · BMC oral health
Introduction Transitioning from a treatment-oriented model to a prevention-focused approach is essential for improving oral health outcomes. This study aimed to assess the feasibility and implementation outcomes of Integrated Oral Health…
View details →Negative / Null Result ReportMedicine
Slowinski J, Lutnick E, Frappa N et al. · 2026 · Foot & ankle international
Background This study aimed to demonstrate long term clinical follow-up and implant survivorship of Salto Talaris-type primary total ankle arthroplasty (TAA) by 1 foot and ankle-trained surgeon at a single institution. Methods Patients…
View details →Negative / Null Result Report
Goicochea-Rios E, Otiniano NM · 2026 · Preprint
Background: To evaluate the effectiveness of an educational intervention in the integral care of patients with diabetes mellitus. Methods A pre-experimental study was carried out with 103 patients with diabetes mellitus treated at Essalud,…
View details →Negative / Null Result ReportMedicine
Ghiri AA, Cavanaugh SJ, Nuñez AA et al. · 2026 · Annals of biomedical engineering
While American football games are played across a wide range of temperatures, current helmet rating protocols assess performance primarily at room temperature. This study evaluates how temperature influences impact attenuation performance…
View details →Negative / Null Result ReportOpen accessMedicine
Hyun HK, Lee OH, Roh JW et al. · 2026 · Yonsei medical journal
Purpose Patients with acute coronary syndrome (ACS) on ticagrelor-based dual antiplatelet therapy (DAPT) have an increased risk of gastrointestinal (GI) bleeding. However, evidence supporting the protective role of proton pump inhibitors…
View details →Negative / Null Result ReportOpen accessMedicine
Li X, Liu C, Wu W et al. · 2026 · Frontiers in neuroscience
Purpose To investigate the short-term effect of a longpass filter on myopic defocus-induced changes in axial length (AL) and choroidal thickness (ChT). Methods This study included 23 young myopic adults. AL and ChT were measured in both…
View details →Failed Experiment ReportMedicine
Shetty PMV, Matzen A, Hille S et al. · 2026 · Scientific reports
Marfan syndrome (MFS) is a connective tissue disorder caused by FBN1 mutations, characterised by aortic aneurysms leading to life-threatening dissections. Asprosin is the C-terminal propeptide of fibrillin-1 that was shown to function as a…
View details →Negative / Null Result ReportMedicine
Lou Z, Yang H · 2026 · European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
OBJECTIVE: The objective of this study was to evaluate the graft success rate, hearing outcomes, and complications associated with three-layer graft myringoplasty for repairing subtotal and total perforations. MATERIALS AND METHODS:…
View details →Negative / Null Result ReportMedicine
Phillipson J, Menson E, Barclay S et al. · 2026 · Archives of disease in childhood
Objective Evaluation of the Medical Mediation Foundation's Conflict Management Programme (CMP)-a structured process for managing conflict. Design Mixed-methods evaluation using Kirkpatrick's framework, a four-level model for evaluating…
View details →Negative / Null Result ReportMedicine
Bachelard L, Blanc N, Michel A · 2026 · BMJ supportive & palliative care
Objective Breast cancer surgery often leads to a high burden of distressing symptoms, underscoring the need for supportive care to help patients throughout the perioperative period. This pilot study aimed to evaluate the feasibility,…
View details →Negative / Null Result ReportOpen accessMedicine
Mosch B, Diers M · 2026 · Pain reports
Introduction Since the outbreak of COVID-19, many studies have investigated long-term consequences associated to the pandemic. Undoubtedly, restrictions and changes in everyday life during that time have had a broad impact on mental health…
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