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Browse the failure-mode index

21,742 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Anticoccidial efficacy of a cinnamon-Rumex nervosus phytobiotic mixture on growth performance, carcass traits, cecal morphology, and cecal health in Eimeria tenella-challenged broilers.

Qaid MM, Al-Garadi MA, Al-Abdullatif AA et al. · 2026 · Poultry science

Coccidiosis remains a major constraint in poultry production; therefore, this study evaluated the anticoccidial efficacy of a phytogenic blend of cinnamon bark and Rumex nervosus leaf in Eimeria tenella-challenged broilers. Birds were…

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Negative / Null Result ReportOpen accessMedicine

Discrepant Intracranial and Extracranial Responses to Tarlatamab in Relapsed Small-Cell Lung Cancer With Untreated Brain Metastases: A Case Report.

Hayashi E, Kano H, Nakamura K et al. · 2026 · Respirology case reports

Small-cell lung cancer (SCLC) has a poor prognosis, and the efficacy of tarlatamab for untreated brain metastases remains unclear. We report a case demonstrating a discrepant response between extracranial and intracranial lesions after…

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Negative / Null Result ReportMedicine

Utility of ultrasensitive, US Food and Drug Administration-approved κ and λ dual in situ hybridization assay in the diagnosis of Hodgkin lymphomas.

Eltahir M, Young K, Younes S et al. · 2026 · American journal of clinical pathology

Objectives Determination of B-cell clonality in formalin-fixed, paraffin-embedded tissues is challenging, especially in cases where tumor B cells are sparse. Flow cytometry is of limited utility in Hodgkin lymphomas, at least in part due…

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Negative / Null Result ReportMedicine

Performance of a new bone-level tapered two-piece zirconia implant manufactured by injection moulding: A pilot preclinical study in minipig mandibles.

Hauck F, Herber V, Moecke S et al. · 2026 · International journal of oral implantology (Berlin, Germany)

Purpose The aim of this pilot preclinical study was to investigate the performance of a novel double-lead thread, conical bone-level ceramic implant manufactured by injection moulding (test group) in comparison to a well-established…

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Negative / Null Result ReportMedicine

Clinical and Neuroimaging Predictors of Outcome and Impact of Surgical Intervention in Cryptococcal Meningitis: An Observational Study.

Qian MY, He LY, Lan P et al. · 2026 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

This study aimed to identify predictors of outcomes and evaluate the therapeutic impact of surgical intervention in CM patients, with a specific focus on the growing HIV-negative population in East Asia. We conducted a single-center…

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Negative / Null Result ReportOpen accessMedicine

Development of a low-cost external fixation system: an off-label solution for resource-limited settings.

Seiser M, Deininger C, Fierlbeck J et al. · 2026 · European journal of trauma and emergency surgery : official publication of the European Trauma Society

Purpose External fixators are essential for the surgical management of long-bone fractures, particularly in resource-limited settings where access to commercial systems is often restricted by cost and logistics. This study aimed to develop…

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Negative / Null Result ReportMedicine

Preoperative prediction of pathological pelvic lymph node metastasis in prostate cancer using an elastic net model integrating clinicopathologic and <sup>68</sup>Ga-PSMA PET/CT features: development and temporal validation.

Chen Y, Gao L, Zheng Z et al. · 2026 · Scientific reports

Preoperative decision-making regarding extended pelvic lymph node dissection (ePLND) in prostate cancer remains challenging. Existing nodal-risk prediction tools are mainly based on clinicopathologic variables and may show suboptimal…

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Negative / Null Result ReportOpen accessMedicine

Enhanced periodontal regeneration using formulated injectable hyaluronic acid with or without PRP: A rat ligature model.

Alghonemy WY, Ahmed NM, Abou Samra AA et al. · 2026 · Journal of oral biology and craniofacial research

Objective To evaluate the regenerative effects of platelet-rich plasma (PRP) combined with 3% low-molecular-weight hyaluronic acid (HA) gel in treating ligature-induced periodontitis in rats. Methods •40 male albino rats divided into 5…

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Negative / Null Result ReportMedicine

Schiff base chromones from natural Benzofuran as potential scaffold for anti-<i>Staphylococcus aureus</i>: synthesis of <i>cis</i> and <i>trans isomers, in vitro and in silico studies</i>.

Selim AAMA · 2026 · Natural product research

Three hydrazone chromones 3a-c ( 3a, b in trans isomer while 3c was a mixture) and three hydrazone furanochromones 7a-c ( 7a in trans while 7b, c in cis ) carrying carboxylic acid or its bioisostere sulphonamide group were synthesised.…

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Negative / Null Result ReportMedicine

Validating ICD code case definitions for condition case ascertainment in multimorbidity measurement: a retrospective chart review.

Kang AJ, Tseng CH, Wei MY · 2026 · The journals of gerontology. Series A, Biological sciences and medical sciences

Background Accurate case ascertainment of chronic conditions is critical for research, clinical decision-making, and population health management, especially for older adults with high multimorbidity. However, validation of ICD-based case…

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Negative / Null Result ReportMedicine

The development of a universal screening measure for young children: Assessing social and emotional competencies in early childhood.

Wadington M, Eklund K, Kilgus SP et al. · 2026 · School psychology (Washington, D.C.)

Research highlights the importance of the early identification of social, emotional, and behavioral concerns in young children; however, there are limitations regarding the usability and technical adequacy of available measures. The…

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Negative / Null Result Report

Frontal Lobe Function, Global Cognition, and 5-Year Swallowing Deterioration After Subthalamic Nucleus Deep Brain Stimulation in Parkinson’s Disease : a retrospective cohort study

Tsuboi R, Murakami S, Miyata M et al. · 2026 · Preprint

Abstract BACKGROUND Dysphagia in Parkinson’s disease (PD) increases aspiration pneumonia risk and is associated with poor prognosis. Although subthalamic nucleus deep brain stimulation (STN-DBS) effectively treats motor symptoms, dysphagia…

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