Use of Botulinum Toxin for the Treatment of Raynaud Phenomenon
Manasa H. Kalluri, BS; Armin Edalatpour, MD; Allison J. Seitz, MD; Brian H. Gander, MD · 2026 · Plastic and Reconstructive Surgery, Global Open
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Summary:. Raynaud phenomenon (RP) is a vasospastic condition of the digital arteries that can cause pain, skin color changes, and functional limitations. Although botulinum toxin is not currently Food and Drug Administration–approved for the treatment of RP, it has been used in refractory RP and has generally been found to be well tolerated. At our institution, incobotulinumtoxinA (Xeomin) and abobotulinumtoxinA (Dysport) are commonly used. Here, we report our experience with the use of incobotulinumtoxinA (Xeomin) in the hand. We present 2 cases of patients with RP in bilateral hands who pres
Abstract by Manasa H. Kalluri, BS; Armin Edalatpour, MD; Allison J. Seitz, MD; Brian H. Gander, MD, Plastic and Reconstructive Surgery, Global Open (2026) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1097/gox.0000000000007424