Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Alina Nussbaumer-Pröll, Bela Hausmann, Maria Weber et al. · 2025 · Antibiotics
Background : The collection of microorganisms that colonize the human genital and urinary tract is referred to as the genitourinary microbiome. Urinary tract infections (UTIs), which predominantly affect women, are linked to alterations in the genitourinary microbiome. Cranberries ( Vaccinium oxycoccos ), rich in proanthocyanidins, and ascorbic acid (vitamin C), known for their urinary acidification properties, are commonly used for UTI prevention. However, their effects on the genitourinary microbiome remain inadequately characterized. This pilot study assesses the genitourinary microbiome co
View details →Negative / Null Result ReportOpen accessAgriculture
Jan Slováček, Šárka Nedomová, Markéta Janík Piechowiczová et al. · 2024 · Czech Journal of Food Sciences
The aim of the study was to define and compare the quality properties of dry-cured heat-treated meat products from the meat of free-living semi-aquatic wildlife species. Eurasian beaver (Castor fiber) and nutria (Myocastor coypus) are wild animals whose presence in the countryside is regulated in the Czech Republic. Basic chemical, microbiological, sensory analyses, and instrumental measurements of the colour and texture of dry-cured sausages (pork, as a control group with 51% lean pork and experimental groups with 51% lean beaver and nutria meat in fresh state) were performed. There were no s
View details →Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Raja Shekhar, Shano Naseem, Jogeshwar Binota et al. · 2021 · Hematology/Oncology and Stem Cell Therapy
Objective/background: B-cell neoplasms are clonal tumors of B cells at various stages of maturation, including diffuse large B-cell lymphoma (DLBCL), chronic lymphocytic lymphoma (CLL), Burkitt lymphoma (BL), lymphoplasmacytic lymphoma (LPL)/Waldenström’s macroglob- ulinemia (WM), splenic marginal zone lymphoma (SMZL), nodal marginal zone lymphoma (NMZL), mantle cell lymphoma (MCL), follicular lymphoma (FL), and hairy cell leukemia (HCL). In this study, we analyzed the frequency of MYD88 L265P mutation and its correlation with clinico-hematological profile in mature B-cell neoplasms. Methods:
View details →Negative / Null Result ReportOpen accessDiseases of the blood and blood-forming organs
Zhen-Yi Jin, Chun-Min Li, Hong Qu et al. · 2024 · Thrombosis Journal
Abstract Objective To compare the predictive efficacy of the PADUA and Caprini models for pulmonary embolism (PE) in gynecological inpatients, analyze the risk factors for PE, and validate whether both models can effectively predict mortality rates. Methods A total of 355 gynecological inpatients who underwent computed tomography pulmonary angiography (CTPA) were included in the retrospective analysis. The comparative assessment of the predictive capabilities for PE between the PADUA and Caprini was carried out using receiver operating characteristic (ROC) curves. Logistic regression analysis
View details →Negative / Null Result ReportOpen accessAstrophysics
Barry F. Madore, Wendy L. Freedman · 2024 · The Astrophysical Journal
Using an updated and significantly augmented sample of Cepheid and tip of the red giant branch (TRGB) distances to 28 nearby spiral and irregular galaxies, covering a wide range of metallicities, we have searched for evidence of a correlation of the zero-point of the Cepheid period–luminosity relation with H ii region (gas-phase) metallicities. Our analysis, for the 21 galaxies closer than 12.5 Mpc, results in the following conclusions: (1) The zero-points of the Cepheid and TRGB distance scales are in remarkably good agreement, with the mean offset in the zero-points of the most nearby distan
View details →Negative / Null Result ReportOpen accessOphthalmology
Yule Xu, Ao Rong, Wei Xu et al. · 2017 · BMC Ophthalmology
Abstract Background To compare the efficacy of intravitreal conbercept and ranibizumab in the treatment of diabetic macular edema (DME) in a real-life clinical practice. Methods This was a retrospective study. Among 62 Chinese patients with DME, 32 patients (36 eyes) received intravitreal conbercept (IVC) injections and 30 patients (32 eyes) received intravitreal ranibizumab (IVR) injections, once a month for 3 months followed by as needed therapy. All participants had at least 12 months of follow-up. We compared the changes in best-corrected visual acuity (BCVA) letter score and central retin
View details →Negative / Null Result ReportOpen accessLanguage and Literature
khawla Alobeidli, Mohammed AL Hourani · 2026 · مجلة الآداب
This study aimed to identify young people's attitudes toward the causes of drug use and its effects on the family and society. Data were collected through a questionnaire distributed to a sample of 143 students at the University of Sharjah. The results showed that less than half of the participants (42.0%) believed that a weak religious conscience is a reason for drug use, while nearly half (41.3%) agreed that bad company is one of the individual factors leading to drug use. Additionally, 30.8% of the participants were uncertain whether traveling for recreation contributes to drug use. The qua
View details →Negative / Null Result ReportOpen accessGynecology and obstetrics
Sepideh Mashayekh-Amiri, Fatemeh Bakouei, Sedighe Esmaeilzadeh et al. · 2019 · Caspian Journal of Reproductive Medicine
Background: The effect of individual sleep hygiene education on sleep quality components remains largely unknown during pregnancy. This study aimed to assess the effect of a short-term sleep hygiene education during prenatal care visits on pregnant women with poor sleep quality. Methods: A quasi-experimental study, designed as a pre- and post-test with a single group, was conducted on 32 pregnant woman with poor sleep quality. All the participants completed the Beck Depression Inventory (BDI), Perceived Stress Scale (PSS), and Pittsburgh Sleep Quality Index (PSQI). The women with good sleep qu
View details →Negative / Null Result ReportOpen accessDentistry
Raji Viola Solomon, Parupalli Karunakar, Deepthi Sarvani Grandhala et al. · 2014 · Journal of Oral Research and Review
Background: Class ll sandwich restorations are routinely performed where conventional Glass ionomer cement (GIC) or Resin-modified GIC (RMGIC) is used as a base or dentin substitute and a light curing composite resin restorative material is used as an enamel substitute. Various authors have evaluated the microleakage of composite resin restorations where glass ionomer cement has been used as a base in class II sandwich restorations, but a literature survey reveals limited studies on the microleakage analysis of similar restorations with biodentine as a dentin substitute, as an alternative to g
View details →Negative / Null Result ReportOpen accessEducation
Amaal Abdulrahman Al-Awydi, Prof. Olfat Abdulaziz Al-Ashi · 2026 · مجلة بحوث التعليم والإبتكار
The study aimed to identify integrity values among secondary school students from the perspective of their teachers. A descriptive survey methodology was used, employing a general data form and an integrity values scale. The study sample (367) is a secondary school teacher in Jeddah Governorate. Results. The overall degree of integrity values promotion across its various dimensions among the study sample, from the teachers' perspective, was high. The dimensions of integrity values promotion were ranked as follows: first, justice; second, dedication to work; and third, honesty—all with high sco
View details →Negative / Null Result ReportOpen accessMedicine
Sun Tae Ahn, Ji Sung Shim, Woong Jin Bae et al. · 2022 · The World Journal of Men's Health
Purpose: We aimed to evaluate the efficacy and safety of penile girth enhancement (PGE) using hyaluronic acid (HA) filler with different physical properties from previous studies. Additionally, we evaluated the clinical impact on ejaculation after PGE. Materials and Methods: This was a prospective, patient/evaluator-blinded, randomized, active-controlled, multicenter trial. Patients recruited between December 2017 and March 2018 were randomly assigned to the HA filler or control group (polylactic acid [PLA] filler). Penile girth, satisfaction level, Premature Ejaculation Profile (PEP), and sel
View details →Negative / Null Result ReportOpen accessOrthopedic surgery
Paul Hoogervorst, MD, Aman Chopra, Zachary M. Working et al. · 2020 · JSES International
Background: Measured shortening of midshaft clavicle fracture fragments is known to be influenced by multiple factors. The influence of radiographic projection on vertical displacement is unclear. The aims of this study were (1) to quantify the difference in measurements of vertical displacement in an absolute, relative, and categorical manner between 5 different projections; (2) to quantify the differences in interobserver and intraobserver agreement using a standardized method for measuring vertical displacement; and (3) to assess the association between categorical and continuous descriptio
View details →Negative / Null Result ReportOpen accessMedicine
Funda Yetkin, Sibel Altunisik Toplu · 2017 · Medicine Science
Despite the advances and a wide range of studies conducted, sepsis is one of the most frequent causes of death in patients with critical health condition. Early diagnosis, rapid and effective treatment are extremely important. Use of procalcitonin (PCT) for this purpose has become widespread and notable recently. Procalcitonin is an important test as point-of-care testing (POCT) just like C-reactive protein (CRP). Procalcitonin is the prohormone of calcitonin. It is released from the parenchymal cells of the liver, kidneys and muscles, and in response to bacterial toxins, it is released from
View details →Negative / Null Result ReportOpen accessGeriatrics
Liwen Bao, Jun Bo, Bo Jin et al. · 2018 · International Journal of Gerontology
Summary: Background: To assess the morbidity and risk factors of contrast induced nephropathy (CIN) in Chinese very elderly patients. Methods: The very elderly patients whose age ≥75 year-old, from North Huashan Hospital, South Renji Hospital and Tongren Hospital, underwent coronary angiography or percutaneous coronary intervention, were included in this study. All of these patients were treated by hydration, those who developed contrast-induced nephropathy were divided into CIN group and the others were divided into non-CIN group. The baseline information was evaluated and serum creatinine wa
View details →Negative / Null Result ReportOpen accessMedicine
Riddhi Vyas, Santhosh Kumar, C M Manasa · 2026 · Saudi Dental Journal
Abstract Periodontal wound dressings have advanced from passive protectants to bioactive agents. This study compared the efficacy of Blue®m gel and a hyaluronic acid (HA) gel in promoting wound healing and controlling postoperative pain after functional crown lengthening surgery. A prospective, randomized, patient and outcome assessor-blinded study was conducted on 40 systemically healthy patients (aged 20–60 years) requiring crown lengthening of posterior teeth. Participants were divided into two groups: Blue®m gel (Group A) and custom-formulated HA gel (Group B). Both gels were applied to th
View details →Negative / Null Result ReportOpen accessBiology (General)
Farahnaz Joukar, Sara Manafi Afkham, Afshin Shafaghi et al. · 2023 · Journal of Current Biomedical Reports
N-acetyl cysteine (NAC) has recently been proposed as an adjunctive therapy for the eradication of Helicobacter pylori infection due to its mucolytic, antioxidant, and antimicrobial properties. This study aimed to evaluate the efficacy of adding NAC to the standard 4-drug regimen consisting of amoxicillin, clarithromycin, pantoprazole, and bismuth subcitrate. In this double-blind, randomized clinical trial, 92 patients with confirmed H. pylori infection were randomly assigned to either the intervention group or the control group (46 patients each) using a randomized block design. All patients
View details →Negative / Null Result ReportOpen accessMedicine
gehad Abd algaliel, Amani Abo alhassein, Sarah Omar · 2024 · Minia Journal of Medical Research
BACKGROUND: Hydroxyzine is an antihistamine that belongs to the first generation of H1 Antihistamines and used in medicine for a variety of purposes. It was introduced into the field of anesthesia for a variety of reasons, including its sedative, antiemetic and anti-allergic properties. Therefore, it's critical to understand how hydroxyzine premedication affects hemodynamic changes in individuals, particularly in younger ones undergoing surgery OBJECTIVES: The objective of this study was to identify the impact of administering hydroxyzine orally before surgery on hemodynamics prior to inductio
View details →Negative / Null Result ReportOpen accessPhilosophy. Psychology. Religion
Alaksandra Šindić, Dijana Andrić, Jurka Lepičnik Vodopivec et al. · 2020 · Nova Prisutnost
In this paper, the authors explore the methodical approach in Catholic religious education in kindergartens in Bosnia and Herzegovina. The theoretical framework is represented by the concept of holistic education. It also includes spiritual education, in the case of this study, religious education. The aim of the empirical part of the research is to determine the methodical elements of religious education in preschool institutions in Bosnia and Herzegovina (types of religious educational activities in religious education of preschool children and their representation, religious climate) and to
View details →Negative / Null Result ReportOpen accessMedicine (General)
Oded Hershkovich, Inga Tetroashvili, Adam Lee Goldstein et al. · 2024 · Medicina
Background and Objectives: The incidence of proximal femoral fractures (PFFs) is rising, causing significant morbidity and mortality. Regional anesthesia (RA)’s benefits include the avoidance of intubation and mechanical ventilation, decreased blood loss, and improved analgesia. General anesthesia (GA) offers improved hemodynamic stability. This study examines the in-hospital post-surgical morbidity and mortality seen in PFFs in a cohort of the elderly undergoing GA or RA. Materials and Methods: This is a retrospective cohort study of 319 PFF patients older than 65 years over a single year. Re
View details →Negative / Null Result ReportOpen accessDentistry
Ebrahim Yarmohammadi, Shiva Kavousinejad · 2024 · Journal of Dental School
Objectives The present study aimed to assess the level of shear bond strength (SBS) of universal adhesives (G-premio Bond Universal (GBU) and All Bond Universal (ABU) on zirconia without surface preparation, zirconia sandblasted by 50-micron aluminum oxide particles, and zirconia glazed by low-fusing ceramics after the thermocycling process. Methods Two Ceramill ZI zirconia blocks were used to prepare 18 cubes with dimensions of 10×10×10 mm. Then, based on the type of surface preparation, these 18 sintered zirconia cubes were classified into three groups of six, including the control group, sa
View details →Negative / Null Result ReportOpen accessSpecial aspects of education
نسرين أحمد الضبيب, زيدان أحمد السرطاوي · 2016 · مجلة التربیة الخاصة والتأهیل
هدفت الدراسة الحالية إلى التعرف على الحالة المزاجية المميزة للتلميذات ذوات صعوبات التعلم في المرحلة الابتدائية، وإلى التعرف على الفروق الدالة إحصائياً في الحالة المزاجية بين التلميذات ذوات صعوبات التعلم، والتلميذات العاديات. وتکونت عينة الدراسة من )٣٠٢) تلميذة، من الصفوف الابتدائية الثلاثة العليا، بواقع )١٤٢) تلميذة من ذوات صعوبات التعلم، و(١٦٠) تلميذة عادية. واستخدم اختبار الحالة المزاجية للأطفال، لطنطاوي، وعجلان (١٩٩٥)، کأداة للدراسة. توصلت النتائج إلى أن أکثر أبعاد الحالة المزاجية لذوات صعوبات التعلم إيجابية بحسب قيم المتوسط الأعلى على التوالي هي: حدة رد الفعل، الاندفاع، مستوى النشاط، الاقت
View details →Negative / Null Result ReportOpen accessNeurology. Diseases of the nervous system
Seiichi Watanabe, Takamichi Taniguchi, Motoko Sugihara · 2021 · Schizophrenia Research: Cognition
This study investigated the effects of the bias known as jumping to conclusions (JTC) on objective functional outcomes as well as subjective assessments of quality of life (QoL) and personal recovery among a sample of patients diagnosed with schizophrenia. Specifically, this study assessed the variables of JTC, psychiatric symptoms, neurocognitive functioning, objective interpersonal and daily activities, vocational domains, subjective QoL, and personal recovery among 94 participants. Results showed that those in the JTC group had significantly lower neurocognitive and functional outcomes (mod
View details →Negative / Null Result ReportOpen accessMedicine
Nilgün Solmaz, Onur Yaya, Feyza Önder · 2014 · Türk Oftalmoloji Dergisi
Objectives: Evaluation of structural alterations of the optic nerve head (ONH) and the retinal nerve fiber layer (RNFL) in patients with ocular hypertension (OHT) and early-stage glaucoma and assessment of the discriminatory diagnostic performance of spectral-domain optical coherence tomography (SD-OCT) Copernicus (Optopol Technology S.A.). Materials and Methods: This study included 59 eyes of a total of 59 patients, 29 of whom were diagnosed with OHT (Group 1) and 30 with early-stage glaucoma (Group 2). The differentiation of early-stage glaucoma and OHT was carried out on the basis of standa
View details →Negative / Null Result ReportOpen accessScience (General)
Fenise Selin Karali, Samet Tosun, Meltem Şen-Aksüt et al. · 2024 · Heliyon
Cyberloafing is the use of (e.g. smartphones, tablets, laptops, and the Internet) for purposes other than work related reasons during work hours. Although cyberloafing in the workplace has been widely investigated, there is relatively a small number of studies on cyberloafing behaviors in educational settings, which refer to students' tendencies to use technology for non-class-related purposes during lectures. The goal of the current study is to determine how frequently and for what purposes speech and language therapy (SLT) students at Biruni University engage in cyberloafing during lectures.
View details →Negative / Null Result ReportOpen accessGynecology and obstetrics
Fariba Mousavi, Sakineh Mohammad-Alizadeh-Charandabi, Mojgan Mirgafourvand et al. · 2023 · Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān
Introduction: Early symptoms of menopause are very common and often very bothersome. Considering the increasing number of women experiencing these symptoms in the world and Iran, there is a growing need to use methods to reduce these symptoms. Therefore, this study was performed with aim to determine the effect of the combined herbal capsules (Menohelp) on reducing the early symptoms of menopause, number and intensity of hot flashes (primary outcomes), and improving sleep quality and quality of life (secondary outcomes) in menopausal women. Methods: In this double-blind trial in Tabriz, 100 wo
View details →Negative / Null Result ReportOpen accessDentistry
Ebrahim Amin Salehi, Haleh Heshmat, Elham Moravej Salehi et al. · 2013 · Journal of Islamic Dental Association of Iran
Background and Aim: Intraoral repair of fractured porcelain is an acceptable method to avoid replacement and therefore saving time and cost. The purpose of this study was to determine the in-vitro shear bond strengths of composite resin to feldspathic porcelain after different durations of sandblasting and to compare the effect of sandblasting with that of hydrofluoric acid (HF ). Materials and Methods : In this in-vitro study, 40 porcelain disks were fabricated and randomly divided into 4 groups (n=10). Porcelain surface in group 1 was etched with 9.5% HF for 2 minutes. Groups 2, 3 and 4 were
View details →Negative / Null Result ReportOpen accessMedicine
Olvera-Maneu S, Regidor M, Serres-Corral P et al. · 2026 · Animals : an open access journal from MDPI
Fecal glucocorticoid metabolites (FGM) are widely used to assess hypothalamic-pituitary-adrenal (HPA) activity in vertebrates, but their applicability to reptiles, and more specifically to snakes, remains poorly explored. The objective of…
View details →Negative / Null Result ReportOpen accessMedical emergencies. Critical care. Intensive care. First aid
Irfan Zubair Shahul Hameed, Darpanarayan Hazra, Priya Ganesan et al. · 2024 · Turkish Journal of Emergency Medicine
OBJECTIVES: In the context of acute hypoxemic respiratory failure (AHRF), ensuring effective preoxygenation and apneic oxygenation emerges as the pivotal approach ensuring for averting hypoxemic adverse events during endotracheal intubation. To investigate this, we conducted an open-label randomized controlled trial, aiming to assess the comparative effectiveness of nasopharyngeal high-flow oxygenation in conjunction with Bag-Valve-Mask (BVM) versus standard BVM preoxygenation in patients experiencing AHRF within the emergency department (ED). METHODS: This prospective single-center, open-labe
View details →Negative / Null Result ReportOpen accessMedicine
Pola farhad hassan, Hamdia Mirkhan Ahmed · 2019 · Diyala Journal of Medicine
Background: Benefits of minimally invasive or laparoscopic procedures include less post operative discomfort. Objective: This study aimed to identify the early postoperative complications of laparscopic cholecystectomy and their association with age, occupation and previous laparatomy. Patients and Methods: 60 female patients diagnosed with having symptomatic gallstone underwent laparscopic cholecystectomy in Pirmam General Hospital, during the period from Jan 2015 to Jul 2015. Surgery done by researchers and after 10 days, the patient interviewed and examined for finding the complications, th
View details →Negative / Null Result ReportOpen accessMedicine (General)
Seyed Hosein Tabatabaei, Seyed Mehdi Kalantar, Mohammad Hasan Akhavan Karbassi et al. · 2021 · Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd
Introduction: Considering the importance of oral health as a part of general health and the role of physicians in community health, the present study was conducted to investigate the relationship between common oral diseases and general body health from the perspective of medical students in Yazd City in 2018. Methods: In this descriptive cross-sectional study, 210 internship and pre-internship students of Shahid Sadoughi University of Medical Sciences in Yazd Cityin 2018 were selected randomly and their knowledge about common oral and dental diseases and its relationship with general body hea
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