Negative / Null Result ReportMedicine
Kuo MC, Younan SA, Williams PJ et al. · 2026 · Techniques in coloproctology
Background Robotic approach is increasingly being used for surgery in Crohn's disease. Robotic ileocolic resection (ICR) for Crohn's disease (CD) is comparable to laparoscopic ICR for short term outcomes; however, no studies have compared…
View details →Negative / Null Result Report
Flora RJ, Bullo J, Talaban J et al. · 2026 · Preprint
Abstract Organochlorine pesticides (OCPs) are persistent organic pollutants known for their environmental stability, hydrophobicity, and strong potential for bioaccumulation. Although many OCPs have been banned or restricted under…
View details →Negative / Null Result ReportOpen accessMedicine
Jankovič P, Chodzyński KJ, Vanrossomme AE et al. · 2026 · Neurology international
Background The risk stratification of unruptured intracranial aneurysms (UIAs) relies largely on static clinical and morphological parameters, which may not fully capture aneurysm-specific wall behavior. ECG-gated four-dimensional computed…
View details →Negative / Null Result Report
Kanack AJ, Mauch EE, Kohlhagen MC et al. · 2026 · Preprint
ABSTRACT Background Monoclonal gammopathy of thrombotic significance (MGTS) is a recently described chronic prothrombotic condition characterized by monoclonal anti-PF4 antibodies that are detected above the polyclonal antibody background…
View details →Negative / Null Result ReportMedicine
Mirza S, Fine L, McClure JA et al. · 2026 · Antibiotics (Basel, Switzerland)
Background Staphylococcus aureus acquires methicillin resistance genes through the SCC mec element. Although spontaneous SCC mec excision has been observed, its frequency, type-specific variation, and responsiveness to environmental…
View details →Negative / Null Result Report
Shahri ZJ, Noda A, Hayashi T et al. · 2026 · Preprint
Abstract Whether developmentally competent pancreatic progenitors can restore pancreatic structure and metabolic function in a defective host environment remains unclear. Here, we used intraplacental transplantation to compare the fate of…
View details →Negative / Null Result ReportMedicine
Buttke DE, Kaplan BS, Jones LC et al. · 2026 · Journal of wildlife diseases
Mycoplasma bovis is a growing threat to American bison (Bison bison) health and restoration efforts, causing significant mortality and disease in affected bison herds. Despite this, little is known about the epidemiology or clinical course…
View details →Negative / Null Result ReportMedicine
Oehring D · 2026 · Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)
Purpose Non-invasive tear film metrics from automated topographers are used increasingly, yet device-specific analytical performance remains incompletely characterised. This study quantified the analytical performance of the Oculus…
View details →Negative / Null Result ReportMedicine
Torkan A, Zoghi M, Foroughimehr N et al. · 2026 · Sensors (Basel, Switzerland)
The rapid global expansion of 5G technology has increased concerns regarding its potential health effects. Postural balance, a complex sensorimotor function reflecting central nervous system integrity, may be susceptible to electromagnetic…
View details →Negative / Null Result Report
Sapkota S, Brewer AN, Underhill A et al. · 2026 · Preprint
Abstract While dominant qualitative disease resistance loci are well known for being easily introgressed in breeding programs and easily overcome by pathogens, the additivity and durability of dominant minor and moderate quantitative loci…
View details →Negative / Null Result ReportOpen accessMedicine
Aguiar Pavesi RO, Boening A, Meyrelles SDS et al. · 2026 · Physiotherapy research international : the journal for researchers and clinicians in physical therapy
Background The 6-minuteute step test is an alternative for estimating cardiorespiratory fitness after stroke. Objective To investigate its measurement properties and minimal detectable change early after stroke. Methods Cross-sectional,…
View details →Negative / Null Result ReportMedicine
Bell KS, Chen R, Weitzner AS et al. · 2026 · Journal of biological rhythms
The circadian system coordinates daily physiology across nearly all tissues to temporally organize metabolism and maintain homeostasis. In the brain, circadian timing regulates neural activity, cellular function, and neuroimmune signaling,…
View details →Negative / Null Result ReportOpen accessMedicine
Scilipoti P, Callenmark M, Garmo H et al. · 2026 · European urology open science
Background and objective There are several methods for estimating prostate-specific antigen (PSA) doubling time (DT), and many men exhibit long periods of undetectable PSA below 0.1 ng/ml after radical prostatectomy (RP). We quantified…
View details →Negative / Null Result Report
Banerjee S · 2026 · Preprint
The Fermi Paradox (“Where is everybody?”) refers to the apparent contradiction between the visualisable abundance of extraterrestrial civilizations and the continued absence of confirmed detections. This work explores whether finite…
View details →Negative / Null Result Report
Sánchez-Valle J, Zambrana C, Navarro-Martínez A et al. · 2026 · Preprint
Multimorbidity is the dominant clinical reality of primary care, yet the temporal dynamics governing when and how persistent comorbidity associations emerge remain poorly characterised. Most large-scale comorbidity studies adopt a single…
View details →Negative / Null Result ReportMedicine
van Caelenberg E, Belpaire A, Dewaele D et al. · 2026 · Clinical and experimental dermatology
Background The Severity of Alopecia Tool (SALT) score is widely used. However, its inter- and intrarater reliability and smallest detectable difference (SDD) have not been rigorously evaluated. Objectives To determine the interrater and…
View details →Negative / Null Result ReportMedicine
Keshavarzi F, Arazpour M, Behzadipour S · 2026 · JMIR biomedical engineering
Background The application of spinal orthoses and local vibration in the treatment of hyperkyphosis is a developing concept. Further research is needed to determine the impact of leaf springs and local vibration techniques on the…
View details →Negative / Null Result ReportOpen accessMedicine
McCaughan KJ, Danyluk MD, Kniel KE · 2026 · Applied and environmental microbiology
Tilling under is a method growers employ in an effort to remediate instances of widespread contamination in fields of crops, but its effectiveness with respect to specific pathogens remains poorly understood. This study had two overarching…
View details →Negative / Null Result ReportOpen accessMedicine
Zhang S, Zhang H, Dong X et al. · 2026 · Frontiers in immunology
Background Radical cystectomy remains a standard curative treatment for muscle-invasive bladder cancer (MIBC). Bladder preservation after systemic therapy without immediate surgery remains investigational and requires careful patient…
View details →Negative / Null Result ReportOpen accessMedicine
Swaine T, Bhagani S · 2026 · Current opinion in HIV and AIDS
Purpose of review Two-drug regimens (2DR) for antiretroviral therapy are increasingly being recommended for people living with HIV to reduce pill burden and reduce short and long-term toxicity. The exclusion of tenofovir and lamivudine or…
View details →Negative / Null Result ReportOpen accessMedicine
Nicklas A, Rudari M, Reidow N et al. · 2026 · Plastic and reconstructive surgery. Global open
Background Postoperative wound healing remains a critical challenge, particularly in complex reconstructions such as free flap surgeries. Despite technical improvements, perfusion-related complications may cause partial flap loss.…
View details →Negative / Null Result Report
Chen A, Daniels W, Huang Z et al. · 2026 · Preprint
Abstract The U.S. federal government undertook a flurry of new actions to monitor and regulate methane emissions beginning in years 2021 and 2022, including the Inflation Reduction Act (IRA). The IRA and Waste Emissions Charge (WEC)…
View details →Negative / Null Result ReportOpen accessMedicine
Antaky CC, Leinbach IL, Plissner JH et al. · 2026 · PloS one
The use of rodenticides is a primary method for eradicating rodents from islands for conservation purposes. Rodenticide residue monitoring is often incorporated into rodent eradication project planning to understand the potential effects…
View details →Negative / Null Result ReportOpen accessMedicine
Aderibigbe AS · 2026 · Poultry science
Despite increasing attention to broiler welfare, there is still limited information comparing physiological stress responses between fast-growing (FG) and slow-growing (SG) genotypes under evolving production conditions. Investigating this…
View details →Replication FailureMedicine
Bao J, Uchiyama T, Kusunoki K et al. · 2026 · Life (Basel, Switzerland)
N -hydroxypipecolic acid (NHP) is a key mobile signal in systemic acquired resistance in plants, and its glycosylation has been proposed to regulate immune signaling. Previous studies have demonstrated that the UDP-glycosyltransferase…
View details →Failed Experiment ReportMedicine
Mathis S, Putzer G, Schnegg L et al. · 2026 · BMC anesthesiology
Background Intraoperative blood salvage (IBS) reduces exposure to allogeneic blood but is accompanied by concerns in oncologic surgery regarding the potential reinfusion of residual tumor cells and subsequent metastatic dissemination. The…
View details →Methods Dead-EndOpen accessMedicine
Aaby D, Sullivan JE, Carmona C et al. · 2026 · Archives of rehabilitation research and clinical translation
Objectives To quantify the Minimum Detectable Change (MDC) and the Minimal Clinically Important Difference (MCID) of the Box and Blocks Test (BBT) and Upper Extremity Fugl-Meyer Assessment (FMA-UE), and to determine whether there is a BBT…
View details →Abandoned Hypothesis
Qiu N, Allenmark F, Chen S et al. · 2026 · Preprint
Real-world distractors occur in environments whose states change at different rates. We asked whether such volatility alters early attentional gating or instead changes the criterion for committing to a response. Observers performed an…
View details →Replication FailureMedicine
Mansell J, Wang X, Jering KS et al. · 2026 · European journal of heart failure
Sex differences in transthyretin cardiac amyloidosis (ATTR-CM) are increasingly recognised; however, women are underrepresented in trials and sex-specific treatment effects remain incompletely understood. We evaluated sex differences in…
View details →Replication FailureOpen accessMedicine
Zhou Y, Zhong Z, Mo H et al. · 2026 · Research and practice in thrombosis and haemostasis
Background Platelet transfusion refractoriness (PTR) is a clinical challenge that can be classified into nonimmunologic and immunologic types, the latter resulting from both platelet alloimmunization and autoimmunity. Recent studies have…
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