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Browse the failure-mode index

21,742 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

A lifespan study on body schema and perceived reaching distance.

Jahanian Najafabadi A, Rastegari A, Imani H et al. · 2026 · Acta psychologica

The plasticity of body representation in response to tool use is a dynamic process that evolves across the lifespan. Research has shown that tools can become integrated into the body representation, effectively being treated as extensions…

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Negative / Null Result ReportMedicine

Effects of yoga on pain, sleep quality, and aerobic endurance in young women with primary dysmenorrhea: A randomized controlled trial.

Bicici Ulusahin S, Celik C, Abut CZ et al. · 2026 · Health care for women international

Primary dysmenorrhea (PD) is a prevalent condition in young women, characterized by menstrual pain, sleep disturbances, and reduced physical activity. Yoga has been suggested as a non-pharmacological intervention. We examined the effects…

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Negative / Null Result ReportMedicine

The Effects of Geranylgeraniol Supplementation on Testosterone in Middle-Aged Healthy Adults: An 18-Week, Single-Group Crossover Placebo-Controlled Trial.

Jurgelewicz M, D'Adamo CR, Malaya CA · 2026 · Integrative medicine (Encinitas, Calif.)

Background Geranylgeraniol (GG) is a naturally occurring isoprenoid that is involved in steroid hormone synthesis, the endogenous production of coenzyme Q10 (CoQ10), healthy muscle function, bone metabolism, and cellular energy production.…

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Negative / Null Result ReportMedicine

Barriers, facilitators and promising interventions for reducing sedentary behaviour during and after stroke rehabilitation - A scoping review.

Te Lindert L, van Meijeren-Pont W, Meesters J et al. · 2026 · Disability and rehabilitation

Purpose Reducing sedentary behaviour (SB) in stroke rehabilitation is essential, yet effects of most interventions remain limited. This review used the Behaviour Change Wheel to identify: (1) barriers and facilitators for reducing SB of…

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Negative / Null Result ReportMedicine

SlROP4 negatively regulates drought tolerance in tomato.

Cheng C, Li M, Sun B et al. · 2026 · Plant science : an international journal of experimental plant biology

Rho-like GTPases of plants (ROPs) regulate diverse cellular processes, but their roles in tomato drought responses are largely unknown. In this study, nine ROP genes were identified in tomato (Solanum lycopersicum). Among them, SlROP4, the…

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Negative / Null Result ReportOpen accessMedicine

Effects of Phenolic-Rich Extra Virgin Olive Oil and Prebiotics on Sarcopenia in Older Adults: FOOP-Sarc Project.

Besora-Moreno M, Jiménez-Ten Hoevel C, Queral J et al. · 2026 · Journal of cachexia, sarcopenia and muscle

Background Management of sarcopenia by nutritional and lifestyle interventions is a challenge. The aim is to assess the effectiveness of a phenolic-rich extra virgin olive oil (EVOO), alone or combined with a prebiotic (PREB)…

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Negative / Null Result Report

Geriatric dentistry in brazilian dental education

Moimaz SAS, Dias GZT, Martins RJ et al. · 2026 · Preprint

Abstract Introduction: The increase in life expectancy in Brazil has led to significant changes in the population pyramid. Considering the different stages of life and the specific oral health conditions associated with older adults,…

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Negative / Null Result ReportOpen accessMedicine

Lumbar Plexus Block

Yao PY, Hendrix JM · 2026

The concept of a regional anesthesia technique that provides neural blockade of the entire lumbar plexus, a lumbar plexus block, dates back nearly 50 years. The first description of such a block by Winnie et al in 1973 was an “inguinal…

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Negative / Null Result ReportMedicine

Pharmacokinetics, pharmacodynamics, and radiomitigative efficacy of IEPA in a non-human primate model of acute radiation syndrome.

Wesolowski R, Asang C, Eibl M et al. · 2026 · International journal of radiation biology

Purpose The acute radiation syndrome (ARS) represents a significant public health threat following nuclear exposure, with limited available medical countermeasures (MCMs). Imidazolyl ethanamide pentandioic acid (IEPA), a novel orally…

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Negative / Null Result ReportMedicine

[Translated article] Is one year follow-up sufficient to assess functional outcomes after rotator cuff repair?

Pasqualini I, Lucero Viviani N, Turan O et al. · 2026 · Revista espanola de cirugia ortopedica y traumatologia

Background Arthroscopic rotator cuff repair (ARCR) traditionally requires a 2-year follow-up to report results. However, most of the recovery occurs within the first year. The aim of this study was to determine if there are clinically…

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Negative / Null Result Report

Acceptability, Implementation Fidelity, and Preliminary Psychological Outcomes of a DBT- Informed Emotional Skills Program in a Secondary School: A Pre–Post Study Among Adolescents in Chile

Gaete J, Romo V, Contreras C et al. · 2026 · Preprint

Abstract Background School-based interventions grounded in evidence-based psychological approaches are increasingly used to promote adolescent mental health. Dialectical Behavior Therapy (DBT) skills training has shown promise; however,…

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Negative / Null Result ReportOpen accessMedicine

IL-18 and MIG increase one year after transition to dolutegravir-based dual therapy despite sustained viral suppression.

Pérez-González A, Alonso-Domínguez J, Martínez-Barros I et al. · 2026 · Frontiers in immunology

Introduction Modern antiretroviral treatment allowed a significant improvement in the life expectancy of people with HIV (PWH), exhibiting robust and sustained efficacy with scarce toxicities, both in two-drug regimens (2DRs) and…

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Negative / Null Result ReportMedicine

Condylar Positional Changes Following Manual Proximal Segment Positioning During Bilateral Sagittal Split Ramus Osteotomy: A Cephalometric Study.

Tanrısever NC, Gökalp H · 2026 · Medicina (Kaunas, Lithuania)

Background and Objectives : Maintenance of condylar position during bilateral sagittal split ramus osteotomy (BSSRO) is important for preserving temporomandibular joint biomechanics and skeletal stability. During surgery, loss of muscle…

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Negative / Null Result ReportMedicine

Efficacy of nonablative radiofrequency on sexual function in postmenopausal women: a randomized clinical trial.

Quezada-Bascuñán C, Ferri-Morales A, Martínez-Vizcaíno V et al. · 2026 · Menopause (New York, N.Y.)

Objective To evaluate the efficacy of nonablative capacitive-resistive monopolar radiofrequency on sexual function and vaginal health in postmenopausal women with genitourinary syndrome of menopause. Methods This was a single-blind,…

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Negative / Null Result ReportOpen accessMedicine

Effect of <i>Bacillus coagulans</i> DSM 32016 (TechnoSpore<sup>®</sup>) Supplementation on Growth Performance and Selected Blood Parameters and Serum Urea in Weaning Danube White Pigs.

Eneva K, Yordanova G, Petrova M et al. · 2026 · Life (Basel, Switzerland)

The present study evaluated the effects of dietary supplementation with Bacillus coagulans DSM 32016 on growth performance, hematological and biochemical parameters, and nitrogen metabolism in weaned Danube White pigs reared under standard…

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Failed Experiment ReportOpen accessMedicine

Probiotics alleviate oral microbiota disruptions induced by <i>Helicobacter pylori</i> eradication with vonoprazan-amoxicillin dual therapy: a randomized double-blind placebo-controlled trial. (An exploratory study).

Wei W, Chen W, Peng R et al. · 2026 · Frontiers in cellular and infection microbiology

Background Helicobacter pylori ( H. pylori ) infection affects approximately half of the global population and has been linked to oral microbiota dysbiosis, while eradication therapies may further disrupt microbial balance. This…

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Negative / Null Result ReportOpen accessMedicine

Salivary responses to an experimental activation of the HPA axis in pigs: Effects of ACTH on analytes related to stress, immune system, inflammation, redox status and metabolism.

Botía M, Cerón JJ, Martínez-Subiela S et al. · 2026 · Veterinary and animal science

Non-invasive biomarkers are essential for assessing stress and welfare. Saliva is a suitable sample type because it can reflect endocrine, immune, inflammatory and redox responses without causing stress from handling. This study examined…

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Negative / Null Result ReportMedicine

No evidence for depletion of circulating lymphocyte populations in primary brain tumor patients receiving radiotherapy alone.

Beekman C, Morita S, Neibart S et al. · 2026 · International journal of radiation oncology, biology, physics

Purpose To investigate the impact of radiotherapy (RT) for brain tumors on circulating lymphocyte populations and understand this from a dosimetric perspective. Methods This prospective study enrolled primary brain tumor patients treated…

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Negative / Null Result ReportMedicine

Comparison of the Effects of Incubator and Radiant Environments on Physiological Criteria and Pain-Stress Levels during Heel Lance in Neonates in the Neonatal Intensive Care Unit: A Randomized Controlled Trial.

Gürsu S, Saydam BK, Kalkanlı O · 2026 · Saudi medical journal

Objectives To compare the effects of incubator and radiant heat on physiological criteria and pain-stress levels during heel prick procedures in newborns in the neonatal intensive care unit (NICU). Methods This randomized controlled…

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