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WASTE Journal

Browse the failure-mode index

21,290 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Failed Experiment ReportMedicine

Identification of novel variants in BRF1 gene from patient with developmental delay, hearing abnormality, and nervous system anomalies.

Yin H, Yu Y, Shen Y · 2024 · International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience

Cerebellofaciodental syndrome characterized with dysmorphic features, intellectual disability, and brain anomalies. Now its clinical spectrum expanded more manifestations including bilateral sensorineural hearing impairment and inner ear…

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Negative / Null Result ReportMedicine

Detection of cross-reactivity of antibodies to the N proteins of feline morbillivirus and canine distemper virus in Japanese cat plasma samples.

Khin STMM, Jafar SM, Ju M et al. · 2025 · Journal of virological methods

Feline morbillivirus (FeMV) is a globally emerging virus that has been linked to chronic kidney disease (CKD) in infected cats. Immunological assays, such as enzyme-linked immunosorbent assay (ELISA), are important for studying the virus…

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Negative / Null Result ReportMedicine

Review and practical excursus on the comparison between traditional statics methods and Classification And Regression Tree (CART) in real-life data: Low protein diet compared to Mediterranean diet in patients with chronic kidney disease.

Calabrese V, Metro D, Alibrandi A et al. · 2025 · Nefrologia

The Classification and Regression Tree (CART) is a supervised learning approach useful used to segment the space of and the predictors/features space into smaller homogeneous regions that are, represented in a decision tree. It computes…

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Negative / Null Result ReportOpen accessMedicine

Platelet antibody detection assays: a single-laboratory comparison of MAIPA, PIFT, and microsphere-based multiplex assays Pak-Lx.

Costa TH, Bonet-Bub C, Kutner JM · 2024 · Hematology, transfusion and cell therapy

Background and objectives The identification of platelet antibodies is essential for diagnosing and managing conditions such as fetal and neonatal alloimmune thrombocytopenic purpura, post-transfusion purpura, and immune platelet…

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Negative / Null Result ReportMedicine

Comparative efficacy of pre-moistened sponges and E-swabs for active surveillance of carbapenem-resistant Acinetobacter baumannii carriage.

Epchtien RE, Temkin E, Masarwa S et al. · 2025 · European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology

We evaluated whether skin sampling with E-swabs is an effective alternative to pre-moistened sponges for detecting carbapenem-resistant Acinetobacter baumannii (CRAB) carriage. Skin samples were collected by sponges with enrichment and…

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Negative / Null Result ReportOpen accessMedicine

Using Next Generation Chemiluminescent Probes to Improve the <i>Plasmodium falciparum</i> <i>in vitro</i> Parasite Reduction Ratio (PRR) Assay.

Hellingman A, Göttle NL, Walz A et al. · 2026 · ACS infectious diseases

Malaria remains a major global health threat, and the emergence of partial artemisinin resistance challenges current treatment regimens. Reliable antimalarial screening assays are therefore essential for identifying new drug candidates.…

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Negative / Null Result ReportOpen accessMedicine

Inferior Sinus Venosus Defect: Inconclusive Transesophageal Echocardiography Clarified by Computed Tomography and Intracardiac Echocardiography.

Hashimoto G, Tsukagoshi Y, Saito A et al. · 2026 · JACC. Case reports

Background Inferior sinus venosus (SV) atrial septal defect (ASD) is a rare interatrial communication, found near the inferior vena cava (IVC)-right atrial (RA) junction, that may be overlooked on transesophageal echocardiography (TEE).…

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Negative / Null Result ReportMedicine

Evaluation of loop mediated isothermal amplification, quantitative real-time PCR, conventional PCR methods for identifying Ascaris lumbricoides in human stool samples.

Thakur M, Mewara A, Lakshmi P et al. · 2025 · Diagnostic microbiology and infectious disease

Ascariasis, caused by Ascaris lumbricoides, is a widespread parasitic infection. Traditional diagnostic methods, such as microscopy, can miss infections with low worm burdens, leading to false negatives. This study compares four diagnostic…

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Negative / Null Result ReportMedicine

Complexities of Atrial Fibrosis Imaging: Exploring Relationships Between Endocardial Voltage, Extracellular Volume, and Sympathetic Innervation.

Wilk B, Lim H, Hicks J et al. · 2025 · JACC. Clinical electrophysiology

Background Atrial fibrillation is associated with abnormal synchronization of left atrial electrical activity and substantially increased risk of myocardial infarction, stroke and heart failure. Objectives This study sought to investigate,…

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Negative / Null Result ReportMedicine

Accuracy of artificial intelligence-based simulation for assessing lung vessels and volume using unenhanced computed tomography.

Fukuta K, Shimada Y, Nagamatu Y et al. · 2025 · European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

Objectives The advantages of preoperative three-dimensional (3D) image simulations, which require enhanced computed tomography (ECT), for anatomical lung resection are well documented. However, the necessity for contrast agent presents a…

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Negative / Null Result ReportMedicine

Investigating disparity in labor epidural analgesia management in black vs. white women: a retrospective case-control study (2018-2022).

Clifton J, Woodward S, Hardcastle S et al. · 2025 · International journal of obstetric anesthesia

Background Disparities in labor epidural analgesia (LEA) management could reduce maternal satisfaction and increase risk. We compared times from the first administration of breakthrough pain medication (top-up) to LEA replacement to…

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Negative / Null Result ReportOpen accessMedicine

Skeletal muscle protein turnover and mitochondrial responses to omega-3 fatty acid supplementation: an update.

Hayden JE, Deane CS · 2026 · Current opinion in clinical nutrition and metabolic care

Purpose of review To critically review recent findings related to the effects of omega-3 fatty acid supplementation on skeletal muscle, with a particular focus on skeletal muscle protein turnover and mitochondrial function. Recent findings…

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Negative / Null Result ReportOpen accessMedicine

Video-Assisted Thoracoscopic Left Lower Lobectomy and Bronchial Foreign Body Removal for Treating a Rare Occult Bronchial Foreign Body in an Adult.

Shi Q, Bao J, Li J et al. · 2025 · Respirology case reports

Occult bronchial foreign bodies are extremely rare in adults. Affected patients typically lack a clear history of aspiration, exhibit no characteristic clinical signs and present with unremarkable chest imaging, often leading to…

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Negative / Null Result ReportOpen accessMedicine

Identifying a Critical Blind Spot: How Commercial AI (CAD) Systems Fail to Detect Faint Ground-Glass Opacities at -730 HU on Low-Dose CT.

Liang S, Wang J, Fu W et al. · 2026 · Diagnostics (Basel, Switzerland)

Objective: The integration of artificial intelligence (AI) into computer-aided detection (CAD) is a major innovation in lung cancer diagnosis. However, its reliability in detecting the earliest radiographic sign-faint ground-glass…

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Negative / Null Result ReportOpen accessMedicine

Sentinel Lymph Node Detection Using SPECT and Gamma Probe in Low-Risk Endometrial Cancer: Efficacy and Factors Associated With Detection Failure.

Asanoma K, Yahata H, Kodama K et al. · 2025 · Asian journal of endoscopic surgery

Introduction This study examined factors that affected sentinel lymph node (SLN) identification of patients with endometrial cancer having a preoperative estimation of low recurrent risk. Methods This study included 97 patients with…

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