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Browse the failure-mode index

21,283 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Could Autism Spectrum Disorder Be Associated With Craniosynostosis?

Still MEH, Alberts A, Nagda P et al. · 2026 · The Journal of craniofacial surgery

Introduction Craniosynostosis is a common pediatric condition that results in variable symptoms that range from asymptomatic cosmetic deformities to severe signs of intracranial hypertension. Little is understood about the relationship…

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Negative / Null Result ReportMedicine

Immersive Haptic Simulation for Psychomotor Skill Acquisition in Preclinical Prosthetic Dentistry: A Randomized Study.

Bandiaky ON, Volteau C, Bihan A et al. · 2026 · The International journal of prosthodontics

Purpose The aim of this study was to evaluate the effect of using the VirTeaSy Dental simulator in conjunction with a virtual reality headset on student performance in conventional fixed prosthodontics simulations. Material and methods The…

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Negative / Null Result ReportOpen accessMedicine

Does closed suction drainage reduce postoperative hematoma and muscle swelling after total hip arthroplasty? A retrospective comparative study using computed tomography.

Asano T, Uemura K, Higuchi R et al. · 2026 · Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs

Purpose Closed suction drainage has been used after total hip arthroplasty (THA) to prevent hematoma, muscle swelling, and complications, but its effectiveness remains controversial. This study evaluated the effects of drains on…

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Negative / Null Result ReportMedicine

Constrained acetabular liner total hip arthroplasty versus conventional hemiarthroplasty for unstable comminuted femoral intertrochanteric fractures in elderly patients with neurological disorders.

Dong M, Liu Y, Wei C · 2026 · BMC surgery

Background To evaluate whether constrained acetabular liners (CAL) used in total hip arthroplasty (THA) reduce the risk of dislocation and related complications in patients with neuromuscular disorders and unstable comminuted femoral…

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Negative / Null Result ReportMedicine

Comparison of Nasal Tip Projection and Rotational Stability between Structural Rhinoplasty with Strut Graft and Preservation Rhinoplasty with Pitanguy Ligament Graft.

Farhadi F, Ahmadpour F, Nezafati S et al. · 2026 · Aesthetic plastic surgery

Background and aim The nasal tip plays a central role in facial aesthetics, and achieving long-term tip stability is a key objective in rhinoplasty. This study compared postoperative tip stability between structural rhinoplasty using a…

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Negative / Null Result ReportOpen accessMedicine

A chlorine releasing solution as an alternative for dental biofilm control.

Telles PYV, Oliveira VC, Geng Vivanco R et al. · 2026 · Scientific reports

To evaluate the antibiofilm activity of a chlorine-releasing solution (CRS) and its in vitro effects on enamel color stability, surface roughness, and microhardness. A mixed biofilm composed of Staphylococcus aureus, Candida albicans, and…

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Negative / Null Result ReportOpen accessMedicine

Comparison of Postoperative Analgesic Efficacy of Two Intrathecal Morphine Doses (75 μg vs 100 μg) for Cesarean Delivery: A Double-Blind Randomized Study.

Veraza JA, Martinez MA, Angulo P et al. · 2026 · Cureus

Background Intrathecal morphine remains a cornerstone of post-cesarean analgesia due to its prolonged spinal effect; however, its use is limited by dose-dependent adverse effects. Contemporary practice trends favor dose minimization, yet…

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Negative / Null Result ReportOpen accessMedicine

Do the Pre-Existing Class III and Class V Composite Restorations Affect the Sealing Ability and Integrity of 3D-Printed Laminate Veneer Margins? An In Vitro Study.

Qaraghuli AM, Cagidiaco EF, Ferrari M · 2026 · Journal of functional biomaterials

Background: The application of veneer restorations over previously composite-restored anterior teeth presents significant clinical challenges, particularly in achieving optimal marginal sealing. Aim: This in vitro study aimed to evaluate…

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Negative / Null Result ReportOpen accessMedicine

Current status of 5-aminosalicylic acid in Crohn's disease treatment: a nationwide survey and analysis of perspectives and practice patterns among inflammatory bowel disease physicians.

Li Y, Chen C, Wang C · 2026 · Frontiers in gastroenterology (Lausanne, Switzerland)

Objective To investigate the perspectives and clinical practice patterns of inflammatory bowel disease (IBD) physicians regarding the use of 5-aminosalicylic acid (5-ASA) in Crohn's disease (CD). Methods A 21-item questionnaire was…

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Negative / Null Result ReportMedicine

Acute effects of the FIFA 11 + kids warm-up program compared with a judo-specific warm-up on explosive and functional performance in youth judo athletes: a randomized crossover study.

Mor H, Şar H, Arslan T et al. · 2026 · BMC sports science, medicine & rehabilitation

Background The FIFA 11 + Kids (FIFA 11+) warm-up program is effective for injury prevention and to enhance sports performance, including vertical jump (VJ), sprint, balance, and agility. However, no previous study has examined the acute…

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Failed Experiment ReportMedicine

Electroacupuncture ameliorates gastrointestinal motility and modulates PLC-IP3 signaling in a rat model of functional dyspepsia.

Yang D, Fang L, Chen Q et al. · 2025 · Acupuncture in medicine : journal of the British Medical Acupuncture Society

Objective The aim of this study was to determine whether electroacupuncture (EA) modulates the phospholipase C-inositol-1,4,5-trisphosphate (PLC-IP3) pathway and platelet-derived growth factor receptor (PDGFR)α + cells in a rat model of…

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Negative / Null Result ReportOpen accessMedicine

Delayed orocecal transit in pediatric gut-brain interaction disorders: A comparative study using the lactulose breath test.

Devanarayana NM, Rajindrajith S, de Silva DGH et al. · 2025 · World journal of gastrointestinal pathophysiology

Background Functional abdominal pain disorders (FAPDs) are common gut-brain interaction disorders with unclear pathophysiology. While impaired gastrointestinal motility is thought to play a key role, small intestinal dysmotility remains…

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Negative / Null Result Report

A population genetic study of Fusarium graminearum , the causal agent of Fusarium Head Blight, provides insights into patterns of inoculum dispersal in wheat fields at a regional scale

Nguyen TBH, Le Floch G, Henri-Sanvoisin A et al. · 2025 · Preprint

ABSTRACT Fusarium graminearum is the primary pathogen responsible for Fusarium Head Blight (FHB) in cereals, causing yield losses and mycotoxin contamination. The present study investigated the genetic diversity and population structure of…

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