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WASTE Journal

Browse the failure-mode index

21,277 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Factors Affecting the Intrafollicular Transfer of Immature Oocytes in Beef Heifers: Does the Injection Matter?

de Faria OAC, Kussano NR, de Faria LC et al. · 2026 · Reproduction in domestic animals = Zuchthygiene

This study aimed to evaluate whether the quality of injection and number of oocytes injected during Intrafollicular Transfer of Immature Oocytes (IFIOT) affect ovulation timing, follicle dynamics, oocyte recovery, nuclear maturation and in…

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Negative / Null Result ReportMedicine

Effect of hydrogen peroxide on microcystin-LR from Microcystis sp.

Ng PH, St-Hilaire S · 2025 · Diseases of aquatic organisms

Microcystis spp. blooms in fish ponds can lead to fluctuations in water parameters, and the microcystin-LR (MC-LR) toxin they produce may pose health risks for fish, as well as consumers. Hydrogen peroxide (H2O2) treatment has been…

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Negative / Null Result ReportMedicine

Minimal Movement Restrictions Do Not Increase Hip Dislocations Following Total Hip Arthroplasty: A Before-and-After Study of 10,357 Patients.

Klaassen AD, Willigenburg NW, Musters JWQ et al. · 2026 · The Journal of bone and joint surgery. American volume

Background Hip dislocation is the most common reason for early revision after total hip arthroplasty (THA). To prevent dislocation, patients are often prescribed movement restrictions following THA; however, these restrictions can be…

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Negative / Null Result ReportMedicine

Efficacy and safety of intensive antihypertensive strategy in patients with low diastolic blood pressure: a secondary analysis of a cluster randomised trial.

Xie Z, Yang C, Yin Y et al. · 2025 · Heart (British Cardiac Society)

Background Intensive blood pressure (BP) control Methods This is a post hoc analysis of the China Rural Hypertension Control Project. Mixed-effect Cox proportional regression and generalised estimating equation models were used to…

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Negative / Null Result ReportMedicine

Clinical predictors of overall survival in elderly oligodendroglioma patients: A Surveillance, Epidemiology, and End Results (SEER) database analysis.

Chandan Reddy S, Mao T, Gendreau J et al. · 2026 · Clinical neurology and neurosurgery

Objective Oligodendrogliomas are typically benign tumors that arise within the white matter tracts of the cerebral hemispheres. Surgical resection, radiotherapy (RT), and chemotherapy (CT) are utilized to prolong survival in patients…

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Negative / Null Result ReportMedicine

PolyDeep Advance 3: Randomized Clinical Trial comparing PolyDeep-assisted and conventional colonoscopy for adenoma detection rate in a colorectal cancer screening program.

Davila-Piñón P, Díez-Martín AI, Nogueira-Rodríguez A et al. · 2026 · Endoscopy

Background and study aim The impact of computer-aided detection (CADe) systems remains uncertain. We evaluated whether PolyDeep, a CADe system, improves adenoma detection rate (ADR) in a colorectal cancer (CRC) screening program. Patients…

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Negative / Null Result ReportMedicine

MRI suspicious lesions in patients under active surveillance: Do systematic biopsies still add value?

Savin Z, Ben-David R, Shem-Tov Dlugy A et al. · 2025 · Canadian Urological Association journal = Journal de l'Association des urologues du Canada

Introduction Active surveillance (AS) requires regular monitoring to detect disease progression. Multiparametric magnetic resonance imaging (mpMRI) and targeted biopsies are commonly used to identify clinically significant prostate cancer…

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Negative / Null Result ReportMedicine

Mitigation of nitrous oxide emissions by 3,4-dimethylpyrazole phosphate and 3,4-dimethylpyrazole succinic acid with reduced fertilizer application time while maintaining cabbage yield in Andosol fields

Akiyama H, Sasaki Y, Tago K et al. · 2025 · Agriculture, Ecosystems and Environment.

Previous studies have reported that nitrification inhibitors are effective in reducing nitrous oxide emissions. However, no studies have reported the effectiveness of 3,4-dimethylpyrazole phosphate, and 3,4-dimethylpyrazole succinic acid…

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Negative / Null Result ReportMedicine

A Prospective Interventional Study to Evaluate the Effect of Hypoxia on Healthy Volunteers and Patients With Inflammatory Bowel Disease: The Altitude Inflammatory Bowel Disease Study.

Vavricka SR, Zeitz J, Madanchi M et al. · 2025 · The American journal of gastroenterology

Introduction Retrospective data suggest association of high-altitude exposure and inflammatory bowel disease flares. Knowledge about underlying pathogenesis remains limited. Methods This prospective interventional trial evaluated the…

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Negative / Null Result ReportMedicine

Heavy episodic drinking and intimate partner violence perpetration: Do interpersonal stress perceptions matter?

Hammett JF, Kirwan M, Chen W · 2026 · Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors

Objective Intimate partner violence (IPV) is a major public health concern. Heavy episodic drinking (HED; i.e., drinking 5+ drinks for men or 4+ drinks for women in a 2-hr period) is a contributing cause of IPV, yet HED does not elicit IPV…

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Negative / Null Result ReportMedicine

Decreasing the Use of As-Needed Antihypertensive Therapy in Hospitalized Patients With Asymptomatic Hypertension.

Lipps KM, Samuel AM, Patel D et al. · 2025 · Journal for healthcare quality : official publication of the National Association for Healthcare Quality

Background Hypertension (HTN) is common in the inpatient setting, with many patients receiving as-needed (PRN) antihypertensive medications (anti-HTN) despite lack of benefit and risk of adverse events. We aimed to decrease PRN anti-HTN…

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Negative / Null Result ReportMedicine

Corneal epithelial morphological changes in orthokeratology lens wearers.

Qasim MSA, Kang P, Evans B et al. · 2026 · Contact lens & anterior eye : the journal of the British Contact Lens Association

Purpose To investigate the utility of in vivo confocal microscopy (IVCM) combined with standardized image grading for identifying early morphological changes in the central corneal and superior limbal basal epithelial cells during…

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Negative / Null Result ReportOpen accessMedicine

Role of Ethnicity and Age in Corneal Curvature and Thickness Changes Following Corneal Cross-Linking for Keratoconus.

Alenezi BM, Khoyratty F, Biswas S et al. · 2026 · Translational vision science & technology

Purpose To investigate the effect of corneal cross-linking (CXL) on corneal curvature and thickness in two different keratoconic populations, one based in the Middle East (Saudi Arabia) and one in Europe (UK), and to explore whether age…

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Negative / Null Result ReportMedicine

Evaluation of the Effect of <i>Astragalus membranaceus</i> Saponins Administration on Knee Function and Cartilage Biomarkers in Healthy Subjects with Knee Discomfort.

Zhuang SR, Leong PY, Chiang HP et al. · 2026 · Nutrients

Objective This study aimed to evaluate the effects of 12 weeks of Astragalus membranaceus saponins (AMS) supplementation on functional performance, knee joint mobility, self-reported outcomes, and biomarkers of inflammation and cartilage…

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Negative / Null Result ReportMedicine

Erythropoietin and Hematological Responses in Recreational Scuba Divers: Insight into the Hyperoxic-Hypoxic Paradox.

Perović A, Juričić G, Bratičević MN et al. · 2026 · Medicine and science in sports and exercise

Purpose During scuba diving, breathing under elevated pressure leads to hyperoxia, which may induce oxidative stress and erythrocyte damage. Hyperoxia may also influence erythropoietin (EPO) production, a phenomenon referred to as the…

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Negative / Null Result ReportMedicine

Compatibility and physicochemical stability of ceftriaxone for injection admixed with pantoprazole sodium and ondansetron hydrochloride in different infusion solutions.

Dobariya A, Patel R, Patel M · 2026 · European journal of hospital pharmacy : science and practice

Objective The study aimed to analyse the physicochemical stability and compatibility of ceftriaxone sodium (CEF) (2mg/mL) with pantoprazole sodium (PAN) (0.08mg/mL) and ondansetron hydrochloride (OND) (0.008mg/mL) in different infusion…

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