21,710 real negative results, null findings, and replication failures. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Pisanò CA, Santino ML, Russotto A et al. · 2026 · iScience
Sleep disorders are common in Parkinson's disease (PD) and respond poorly to current pharmacological treatments, partly due to limited understanding of their underlying mechanisms. Using polysomnographic recordings, we investigated the…
View details →Duke DJ, Wang H, Rao L et al. · 2026 · International journal of pharmaceutics
Design of the mouthpiece of a pressurised metered dose inhaler is generally informed by patient needs, followed by manufacturing and product differentiation considerations. However, relatively few studies have investigated whether the size…
View details →Gonsalves V, Flake C, West D et al. · 2026 · Annals of dyslexia
Practitioner knowledge about dyslexia is related to improved educational practices, but few measures of dyslexia knowledge have been validated with rigorous processes. The current study developed the Dyslexia Assessment and Intervention…
View details →Wang HK, Huang SH, Li CY et al. · 2026 · The journal of spinal cord medicine
Context/objective The optimal timing of surgical decompression for traumatic spinal cord injury (TSCI) remains uncertain. This study evaluated the association between ultra-early decompression and neurological outcomes, focusing on early…
View details →Dantagnan CA, Salem C, Charavet C et al. · 2026 · American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics
Introduction This study aimed to compare the effect of artificial saliva (AS) aging on the trueness and precision of direct-printed aligners vs thermoformed aligners. Methods Four types of aligners were manufactured from the same reference…
View details →Chen Z, He S, Li C et al. · 2026 · Preprint
Abstract Objectives To evaluate the diagnostic accuracy of anterior joint space widening on Cone Beam Computed Tomography (CBCT) for identifying anterior disc displacement (ADD) of the temporomandibular joint (TMJ), using Magnetic…
View details →Bettiol NB, de Carvalho FA, Siessere S et al. · 2026 · Dentistry journal
Background: The relationship between facial aesthetic procedures and changes in the stomatognathic system has attracted increasing interest, motivating investigations into their functional and structural impacts. This longitudinal…
View details →Lee D, Koo J, Jeon H et al. · 2026 · AAPS PharmSciTech
Tofacitinib (Tofa), a Biopharmaceutics Classification System Class III drug, exhibits pH-dependent solubility and a strong tendency to agglomerate, potentially affecting tablet uniformity, in vitro dissolution behavior, and in vivo…
View details →Nguyen DV, Nguyen HTT · 2026 · JACC. Asia
Background Evidence regarding the effect of mineralocorticoid receptor antagonist therapy on the risk of new-onset diabetes remains inconsistent. Objectives This study aimed to examine the effect of spironolactone on the risk of incident…
View details →Baldeon-Calisto M, Perez-Pérez N, Guevara C · 2026 · Physics in medicine and biology
Objective. Vision foundation models (FMs) have shown strong potential for adapting to diverse downstream tasks without specialized fine-tuning. However, their performance in head and neck cancer (HNC) tumor segmentation remains…
View details →Ansorena X, Quiñones I, Hernandez M et al. · 2026 · Preprint
Purpose: We present the clinical case of AB, a right-handed individual who experienced a stroke affecting the right temporo-parietal cortex, resulting in phonological short-term memory (pSTM) impairment. Functional MRI revealed…
View details →Marghmaleki MS, Rostami S, Mojtahedi MF et al. · 2026 · Recent advances in inflammation & allergy drug discovery
Introduction The study aimed to investigate the effect of vitamin D (Vit D) supplementation on serum levels and gene expression of interleukin-10 (IL-10) and IL-35 in women with unexplained recurrent spontaneous abortion (uRSA). Methods In…
View details →Bartsch F, Scholz C, Gröger LK et al. · 2026 · Frontiers in surgery
Background Since the first data of the BILCAP trial was presented in 2017, capecitabine became standard adjuvant treatment for intrahepatic cholangiocarcinoma (ICC). For ICC, the efficacy of capecitabine on survival outcomes remains…
View details →Ferrillo M, Daly K, Pandis N et al. · 2026 · International orthodontics
Introduction Extractions may be helpful in the relief of crowding and in incisal retraction. While extractions may help to control the vertical dimension, their effect is not clear-cut. Four premolar extractions (FPE) may be more potent in…
View details →Lasbareilles C, Mancini V, Pogosyan A et al. · 2026 · Preprint
BACKGROUND Theta-gamma phase-amplitude coupled (θγ-PAC) oscillations in primary motor cortex (M1) have been shown to support motor skill acquisition. Past research has shown that driving gamma activity at the theta peak (TGP), but not the…
View details →Ansorena X, Quiñones I, Hernandez M et al. · 2026 · Preprint
Purpose: We present the clinical case of AB, a right-handed individual who experienced a stroke affecting the right temporo-parietal cortex, resulting in phonological short-term memory (pSTM) impairment. Functional MRI revealed…
View details →Chittenden C, Bills WR, Dangal NK et al. · 2026 · Plant disease
This study investigates the impact of seeding rate, cultivar architecture, and fungicide application on soybean canopy penetration, disease severity, and yield. Field trials conducted in Iowa in 2022, 2023, and 2025 included two soybean…
View details →Yu J, Mangal U, Liu J et al. · 2026 · Preprint
Abstract Objectives This study evaluated the effects of restorative materials and intraoral scanners on the mesh data quality of dental models and the accuracy of 3D-printed clear aligners. Materials and methods Reference scan data were…
View details →Kijkasiwat P, Phoemsanam A, Yang L et al. · 2026 · Preprint
Abstract This study examines the relationship between internal financial factors and the profitability of banks in Laos. Data were collected from 27 commercial banks that publicly disclosed their annual financial statements over a…
View details →Ebadi Hasan Abadi M, Ghahremani Z, Borzouei A et al. · 2026 · Scientific reports
The development of pure homozygous lines is a critical objective in plant breeding, yet conventional methodologies for achieving this goal are time-consuming. Double haploid (DH) technology suggests a powerful technique for producing pure…
View details →Zhu J, Huang L, Zheng R et al. · 2026 · Scientific reports
Although quality of life (QOL) improves over time for most pancreatic cancer patients after surgery, some patients may show different patterns of QOL. Beyond determining distinct QOL trajectories, identifying characteristics of patients…
View details →Güngör İlhan GM, Erdoğan Y, Özbey İpek H et al. · 2026 · Nigerian journal of clinical practice
Background This study aimed to evaluate the effect of different cement types on the fracture strength of zirconia crowns fabricated at varying occlusal cement gap widths for primary molars using a computer-aided design and manufacturing…
View details →Luo G, He T, Yin D et al. · 2026 · Journal of environmental management
Foliar application technology has received considerable research attention due to its potential to mitigate the accumulation of heavy metals such as cadmium and lead in crops. However, to date, there are very few inorganic foliar sprays…
View details →Hasan N, Harisudin M, Kusnandar K et al. · 2026 · Preprint
Abstract Moving from risk perception to concrete farm action remains a central challenge in sustainable agriculture. Farmers may be aware of environmental and health risks, but such awareness does not automatically translate into…
View details →Park S, Kim J, Kwon Y et al. · 2026 · Preprint
The striatum, a critical hub for motor skill learning, is located deep within the subcortical region, making noninvasive stimulation particularly challenging. Nevertheless, recent studies suggest that transcranial magnetic stimulation…
View details →Gu Z, Wang M, Liang Z et al. · 2026 · Preprint
Consistent behavioural differences among individuals have been documented across many animal taxa, yet their developmental consequences remain less clear in domestic production systems. This gap is especially relevant in managed…
View details →Yagdiran B, Kirisci B, Cekmen N et al. · 2026 · BMC pulmonary medicine
Purpose Pulmonary hypertension (PH) is associated with systemic hemodynamic changes that may influence graft perfusion following liver transplantation (LT). In this study, we aimed to evaluate whether pre-transplant PH risk, as estimated…
View details →Savariau L, Tasdemir N, Thale I et al. · 2026 · Preprint
Invasive lobular carcinoma (ILC) is the most frequently diagnosed special histological subtype of invasive breast cancer and accounts for 10 – 15% of all cases. The pathognomonic hallmark of ILC is the genetic loss of E-cadherin ( CDH1 )…
View details →Abd Elhamed HB, Mohamed Ahmed EA, Youssif EF et al. · 2026 · Journal of clinical medicine
Background and Objectives : Chronic nonspecific neck pain (NSNP) is among the most common musculoskeletal disorders. Global postural re-education (GPR) might be effective in decreasing neck pain (NP) and dysfunction and improving forward…
View details →Ashraf N, Hong Q, Guo Z et al. · 2026 · BMC cancer
Background Hepatocellular carcinoma (HCC) is a global health burden and hepatitis B virus (HBV) infection is a common cause. Antiviral therapy has the possibility to reduce the incidence of HCC, and recurrence of HCC after surgical…
View details →