21,277 real negative results, null findings, and replication failures. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Abdulridha GAO, Fadhel AS, Al-Kinany SQ et al. · 2026 · Journal of neuroimmunology
Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system characterized by leukocyte infiltration, immune activation, demyelination, and axonal injury. This case-control observational study aimed to investigate…
View details →Baltu D, Taş N, Alıcı N et al. · 2026 · Pediatric nephrology (Berlin, Germany)
Background Although acetazolamide is the main medical treatment for idiopathic intracranial hypertension (IIH), data on acetazolamide-induced metabolic acidosis and its long-term outcomes are limited. This study aimed to investigate the…
View details →Rinaldi V, Ridolfi F, Finotello R et al. · 2026 · Veterinary medicine and science
Hypertrophic osteopathy (HO) is a paraneoplastic or parainflammatory syndrome characterised by painful periosteal new bone formation and soft tissue swelling, most commonly associated with thoracic neoplasia. The pathogenesis of HO remains…
View details →Mano N, Mori K, Kuwabara T et al. · 2026 · Annals of biomedical engineering
Purpose Diverse gait patterns in individuals with stroke require personalized rehabilitation to improve paretic propulsion (Pp), which reflects gait function. However, the gait characteristics associated with Pp have not been fully…
View details →Jaime-Jorge S, García-Ael C, Azanza G et al. · 2026 · European journal of investigation in health, psychology and education
This paper analyses associations between psychological health at work and life satisfaction among employees. Specifically, it investigates the association between work stress and emotional exhaustion and explores whether connectedness to…
View details →Allfelt A, Bendahl PO, Alkner S et al. · 2026 · Preprint
Abstract Background Invasive lobular carcinoma (ILC) is a risk factor for positive margins after breast-conserving surgery (BCS). This retrospective observational study examined whether the presence of residual cancer cells in re-excision…
View details →Lu B, Wang P, Hu J et al. · 2026 · Environmental pollution (Barking, Essex : 1987)
Wetland interfaces regulate greenhouse-gas exchange and carbon retention, yet contaminant exposure may disrupt the relationship between these two processes. Whether aqueous perfluorooctane sulfonate (PFOS), a persistent aquatic…
View details →Shioiri H, Takahashi T, Matsumoto T · 2026 · International orthopaedics
Purpose To investigate factors associated with achieving both postoperative knee flexion range of motion (ROM) ≥ 125° and Numerical Rating Scale (NRS) pain score ≤ 1 at one year after posterior cruciate-retaining total knee arthroplasty…
View details →Liu S, Tan Y, Zang L · 2026 · Healthcare (Basel, Switzerland)
Background/Objectives: Climate change worry is an emerging concern in youth mental health, but little is known about how it is associated with positive psychological functioning among university students. This study examined whether…
View details →Fisayo T, Evans C, Mutasa K et al. · 2026 · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Background Cytomegalovirus (CMV) co-infection is associated with mortality in adults with HIV, but whether CMV is associated with mortality in children with HIV remains uncertain. Methods In 498 children (median age 6.3 years,…
View details →Mayo AK, Beaudoin JJ, Woodhead JL et al. · 2026 · Clinical pharmacology and therapeutics
Obeticholic acid (OCA), a synthetic analog of chenodeoxycholic acid, was approved in 2016 for the treatment of primary biliary cholangitis. Early clinical trials revealed elevated liver biomarkers in healthy subjects receiving…
View details →Frey L, Grunwald S, Ruckes C et al. · 2026 · European urology open science
Background and objective Metastatic testicular germ cell tumors (mTGCTs) are treated with combination chemotherapy (Cx) containing bleomycin (BEP [bleomycin, etoposide, and cisplatin]). Bleomycin-induced pulmonary toxicity (BPT) is a…
View details →Liang D, Tong Y, Li F et al. · 2026 · Cerebrovascular diseases (Basel, Switzerland)
Introduction General anesthesia (GA) with endotracheal intubation is standard during endovascular treatment (EVT) for acute ischemic stroke (AIS), but the optimal timing for post-procedural extubation remains unclear. Methods In this…
View details →Radha S, Arends M, Kislinger G et al. · 2026 · PLoS biology
Rapid information processing in complex organisms depends on myelin, which consists of a multilamellar membrane that tightly adheres to the axonal surface along the internode and at paranodal loops, where specialized adhesion proteins…
View details →Mirda D, Hao J, Dungan M et al. · 2026 · Cancers
Background : Lynch syndrome (LS) is the most common hereditary cause of colorectal cancer (CRC), and colorectal surveillance has been shown to reduce death from CRC in this high-risk population. This study aimed to examine adherence to…
View details →Ito K, Fujii M, Oba Y et al. · 2026 · International orthopaedics
Purpose To determine changes in low back pain (LBP) after total hip arthroplasty (THA), identify preoperative factors associated with residual LBP and LBP improvement, and clarify the association between residual LBP and patient-reported…
View details →Hamasaki H, Taxiarchi V · 2026 · Preprint
Aims Sarcopenia and sarcopenic obesity are associated with increased risks of cardiovascular (CV) disease and mortality. This study examined the associations of body composition and daily physical activity with mortality, CV events and…
View details →Cunningham PM, Hayes JE · 2026 · Appetite
Widespread nutrition advice instructs consumers to drink water with meals to increase fullness and reduce energy intake. However, recent data indicates greater water intake is associated with more food intake at a meal, not less. Switching…
View details →Charoenrat B, Sungkarat S, Phirawatthakul C et al. · 2026 · BMC geriatrics
Background Neck pain is associated with altered postural and gait performance in older adults. Smartphone use may further challenge postural and gait control due to additional cognitive and motor demands. This study aimed to investigate…
View details →Bertholdi Filho SU, Telles JP, Melo IM et al. · 2026 · Critical care science
Objective To evaluate the efficacy of monotherapy versus combination therapy in the treatment of carbapenem-resistant Acinetobacter baumannii infections. Methods A retrospective observational study was conducted in two tertiary hospitals…
View details →Tan Y, Cheng F, Li P et al. · 2026 · Epigenomics
Background Glioblastoma (GBM) is epigenetically heterogeneous, and previous long noncoding RNA (lncRNA) methylation studies have often begun from tumor-wide screens. We asked whether brain-enriched lncRNAs show promoter…
View details →Terrinoni M, Caputo V, Palisciano M et al. · 2026 · Genes
Background/Objectives: Cervical cancer is mainly driven by persistent infection with high-risk human papillomaviruses (HPV), particularly HPV16 and HPV18. Despite advances in cytology, HPV-DNA testing and vaccination, challenges remain in…
View details →Jameson AT, Hur WS · 2026 · Current opinion in hematology
Purpose of review Metabolic diseases, including obesity, metabolic dysfunction-associated steatotic liver disease (MASLD), and diabetes, are associated with increased thrombotic risks. Conversely, components of the hemostatic system…
View details →Holleman J, Kåreholt I, Kivipelto M et al. · 2026 · Gerontology
Introduction Physical and cognitive impairment constitute large burdens of disease in older adults, but may be preventable through reduction of modifiable risk factors. While chronic stress has been linked to cognitive and physical…
View details →Ahmadi T, Ghorbanzadeh V, Hosseinnejad E et al. · 2026 · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Doxorubicin remains an indispensable component of many chemotherapy regimens; however, its clinical use is limited by dose-dependent cardiotoxicity that may progress to dilated cardiomyopathy and heart failure. In the present study, we…
View details →Mogoș RA, Carauleanu A, Vasilache IA et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives : Autoimmune thyroiditis (AIT) is often reported patients with PCOS, and may co-occur with altered metabolic risk markers. The aims of this study were to assess baseline differences according to thyroid…
View details →Han Y, Zhong C, Lu Z et al. · 2026 · Scientific reports
Abdominal massage (AM), a traditional Chinese medicine treatment, is gradually being recognized in clinical practice for its ability to improve the symptoms of obesity and type 2 diabetes mellitus (T2DM) in clinical practice. This study…
View details →Wang J, Soley BDS, Xiao Y et al. · 2026 · Cancer research communications
Cancer-associated fibroblasts (CAFs) display remarkable plasticity, enabling them to adapt to therapeutic and mechanical stress within the tumor microenvironment (TME). Here, we identify a shared mechanotransduction pathway by which BRAF…
View details →Mehedinti R, Earar K, Stefanescu A et al. · 2026 · Preprint
Background: and Objectives: Long-standing contact between oral mucosa and restorative materials may be associated with adaptive epithelial and stromal remodeling. This study evaluated non-dysplastic epithelial plasticity and cumulative…
View details →Chan SWY, Wang R, Liu J · 2026 · Psychological assessment
Adult-reported surveys are more cost-effective for measuring children's executive function (EF) skills than direct child assessments, which are often resource-intensive. This study examined the extent to which teacher and parent reports…
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