21,266 real negative results, null findings, and replication failures. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Zaki HF, Bishri J, Abdul Muqtadir M et al. · 2026 · Experimental eye research
Background Cone-rod dystrophy (CORD) and achromatopsia (ACHM) are inherited retinal dystrophies for which conventional adeno-associated virus (AAV) gene augmentation has important limitations, particularly in autosomal-dominant…
View details →Znabu BF, Atif Z, devkota P · 2026 · Preprint
Abstract The brain continuously generates predictions about incoming sensory input and produces characteristic neural responses when those predictions are violated. In EEG oddball paradigms, these prediction-error responses manifest as the…
View details →Blokzijl J, Kuijlaars IAR, Pisters MF et al. · 2026 · Haemophilia : the official journal of the World Federation of Hemophilia
Introduction The Haemophilia Activities List (HAL) is a disease-specific patient-reported outcome measure (PROM) that is widely used in both healthcare and research in people with inherited bleeding disorders (PWBD), but information on…
View details →Vardanega R, Lüdtke FL, Loureiro L et al. · 2026 · Journal of agricultural and food chemistry
This study investigated whether coencapsulation of cannabidiol (CBD) and piperine (PIP) in food-grade nanostructured lipid carriers (NLCs) enhances the CBD oral bioavailability. NLCs containing long-chain fatty acids were formulated with…
View details →Unal RU, Ozhan O, Balkaya ES et al. · 2026 · Scientific reports
Sepsis frequently leads to cardiac dysfunction driven by oxidative stress (OS), inflammation, and conduction abnormalities. Nebivolol (NEB), a selective β1-blocker with vasodilatory and antioxidant properties, has shown organ-protective…
View details →Perez SB, Lau JA · 2026 · Ecology
Identifying the factors mediating the resilience and invariability of plant communities and their associated ecosystem functions is critical to understand the ecological impacts of climate change. Prior work has explored how classic…
View details →Wanjiku C · 2026 · Preprint
Abstract Background Timely initiation of breastfeeding within one hour of birth reduces neonatal mortality and supports optimal child development. Women who deliver by cesarean section (CS) face disproportionate barriers to early…
View details →Biswas A, Zidan H, Kolodzey L et al. · 2026 · Regional anesthesia and pain medicine
Background Video-assisted thoracoscopic surgery (VATS) offers numerous advantages over open surgery; nevertheless, it remains associated with significant postoperative pain. Multiple regional anesthesia techniques have been explored, and…
View details →Kominsky E, Ansari M, Moore M et al. · 2026 · Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
Objective To determine the association of positive margins and adjuvant radiotherapy on overall survival in parotid gland adenoid cystic carcinoma. Study design Retrospective cohort analysis. Setting National Cancer Database from 2004 to…
View details →Buldur M, Sezer B · 2026 · Dental traumatology : official publication of International Association for Dental Traumatology
Background/aim Artificial intelligence-based chatbot systems are increasingly used for dental emergency guidance, yet the clinical value of sequential consultation remains unclear. This study investigated whether response order influences…
View details →Ekhaguere OA, Kesman R, Reiter J et al. · 2026 · The Journal of pediatrics
Objective To evaluate whether static ultrasound improves first-attempt, nontraumatic lumbar puncture (LP) success compared with the traditional landmark technique in infants admitted to a neonatal intensive care unit (NICU). Study design…
View details →Nguyen NMC, Ryu H, Park JY et al. · 2026 · Preprint
Abstract Methylorubrum extorquens formate dehydrogenase I (Me-FDH1) is a tungsten-dependent heterodimeric enzyme with high activity for CO2/formate interconversion, making it an attractive biocatalyst for carbon capture, formate…
View details →Vranceanu AM, Szapary C, Crean M et al. · 2026 · The Gerontologist
Background and objectives We tested the feasibility and preliminary effects of the Mindfulness Self-Compassionate Care (MASC) program for dementia caregivers' stress triggered by the care recipients' neuropsychiatric symptoms. Research…
View details →Velez T, Badaki-Makun O, Hirsch D et al. · 2026 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Objective Early identification of mortality risk in critically ill children with suspected infection remains challenging. Whether severity scores (SIRS, pSOFA, Phoenix) add incremental value beyond data-derived physiologic features in…
View details →Al-Ibraheem A, Moghrabi S, Alsyouf B et al. · 2026 · Cancers
Background : [ 68 Ga]Ga-FAPI PET/CT demonstrates high sensitivity for tumor detection but limited specificity because benign fibro-inflammatory conditions may also show tracer uptake. Dual-time-point imaging has been proposed to improve…
View details →Embry KR, Jayaraman C, Yang C et al. · 2026 · Journal of neuroengineering and rehabilitation
Background Powered knee and ankle prostheses generate mechanical energy to replicate biological leg function, yet direct comparisons with more commonly prescribed microprocessor-controlled knee prostheses are limited by methodological…
View details →Herrera-Elizondo JL, Jiménez-Castillo RA, García-Compeán D et al. · 2026 · Revista de gastroenterologia de Mexico (English)
Introduction and aims The usefulness of metoclopramide for improving endoscopic visualization in upper gastrointestinal bleeding (UGIB) is controversial. Our primary aim was to evaluate the utility of metoclopramide 20 mg/IV for endoscopic…
View details →Tamura T, Abe S, Matsui H et al. · 2026 · Journal of affective disorders
Background Dopaminergic dysfunction has been implicated in major depressive disorder (MDD), but dopamine transporter (DAT) imaging studies using conventional mean binding have yielded inconsistent findings. One possible contributor is that…
View details →Yu X, Yuan Y, Zhao S et al. · 2026 · The Journal of bone and joint surgery. American volume
Background Hip fracture volumes are rising with population aging, and inadequate analgesia following hip fracture surgery has been shown to impede early mobilization and recovery. Liposomal bupivacaine (LB) may extend analgesia, but…
View details →He Z, Lyu S, Huang M et al. · 2026 · Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery
Objective: To investigate the expression of HPV 6/11 in NIP tissues and evaluate the adjuvant therapeutic effect of interferon-α gel on HPV-positive NIP patients. Methods: Forty-two newly diagnosed Nasal Inverted Papilloma（NIP） patients…
View details →Naghizade B, Özyazgan İ, Bozkurt F et al. · 2026 · Journal of plastic, reconstructive & aesthetic surgery : JPRAS
Background Autologous fat grafting is widely used in plastic surgery, but graft survival remains unpredictable, particularly under compromised conditions such as cigarette smoking. Smoking impairs microcirculation and tissue oxygenation,…
View details →Taylor-Williams O, Nossent J, Inderjeeth CA · 2026 · The Journal of rheumatology
Objective Rheumatoid arthritis (RA) is a potentially devastating autoimmune disease associated with multiple comorbidities, including osteoporosis and cardiovascular disease, which exert significant morbidity and mortality burdens. Despite…
View details →Alkhatatbeh T, Alkhatatbeh A, Liao Y et al. · 2026 · Annals of the New York Academy of Sciences
Intra-articular hyaluronic acid (IAHA) injections are used for knee osteoarthritis, but clinical response is highly variable. This study evaluated whether quantitative magnetic resonance imaging (MRI) radiomics provides incremental…
View details →Schlaepfer CH, Lange SM, Lau GA et al. · 2026 · JAMA pediatrics
Importance People with spina bifida historically have worse survival. Despite health care improvements, survival improvement data are mixed. Objectives To compare survival for people with spina bifida to an unaffected cohort and to…
View details →Isaacs J, Bendale G, Reiter C et al. · 2025 · Journal of reconstructive microsurgery
Polyethylene glycol (PEG) hydrogel is capable of fusing transected axons and restoring axonal continuity. The technique requires precise nerve coaptation alignment and stability, which is difficult to achieve utilizing conventional…
View details →Kar N, Rana SS, Gupta R et al. · 2026 · Pancreas
Background and aims Endoscopic ultrasound (EUS)-guided drainage using a lumen-apposing metal stent (LAMS) has become the standard of care in managing symptomatic walled-off necrosis (WON). However, the role of nasocystic drainage (NCD) in…
View details →Morningstar M, Edwards M, Yang L et al. · 2026 · CJEM
Objectives To systematically identify and describe optimal methodology used to improve the diagnostic accuracy of high-sensitivity cardiac troponin for diagnosis of myocardial infarction in patients with kidney dysfunction. Methods…
View details →Sroypechr K, Hutchinson C, Satheannoppakao W et al. · 2026 · BMC nutrition
Background The folate status of women of reproductive age (WRA) in Thailand is suboptimal for reducing risk of neural tube defects (NTD). This research aimed to compare the effect of dietary folate education based on the health belief…
View details →Thurm C, Keating LH, Raja MU et al. · 2026 · Respiratory medicine
Rationale Although low-dose computed tomography (LDCT) performed for lung cancer screening (LCS) frequently identifies previously unrecognized significant incidental findings (SIFs), the most effective way to report these findings remains…
View details →Hong S, Lee S, Park JS et al. · 2026 · Journal of clinical medicine
Background : We evaluated whether adding S100B to NSE improved discrimination or high-specificity rule-in of poor neurological outcome after out-of-hospital cardiac arrest (OHCA). Methods : In this single-center retrospective cohort study,…
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