Pioglitazone does not enhance exogenous glucose oxidation or metabolic clearance rate during aerobic exercise in men under acute high-altitude exposure.
Margolis LM; Wilson MA; Drummer DJ; Carrigan CT; Murphy NE; Allen JT; Dawson MA; Mantzoros CS · 2024 · American journal of physiology. Regulatory, integrative and comparative physiology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Insulin insensitivity decreases exogenous glucose oxidation and metabolic clearance rate (MCR) during aerobic exercise in unacclimatized lowlanders at high altitude (HA). Whether use of an oral insulin sensitizer before acute HA exposure…
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Metadata source: Europe PMC · DOI 10.1152/ajpregu.00064.2024