Negative / Null Result Report
Peker¹ I, Özdemir¹ O, Kandemir¹ C et al. · 2026 · Preprint
Abstract Aim Prolonged intensive care unit (ICU) stay after coronary artery bypass graft (CABG) surgery is a significant clinical problem associated with increased morbidity, mortality, and healthcare costs. The aim of this study was to…
View details →Negative / Null Result ReportOpen accessMedicine
Zeren G, Bakır EO, Tufaro V et al. · 2026 · Journal of cardiovascular development and disease
Intravascular imaging (IVI) was introduced 35 years ago to assess coronary artery pathology and plaque vulnerability. However, from its first applications it became apparent that it can also be useful in percutaneous coronary intervention…
View details →Negative / Null Result ReportMedicine
Kim HK, Huang DT, Al-Khafaji A · 2026 · Journal of intensive care medicine
Acute liver failure (ALF) and acute-on-chronic liver failure (ACLF) both have high mortality rates without liver transplantation. Artificial liver support systems may benefit patients with liver failure, serving as a bridge to…
View details →Negative / Null Result ReportMedicine
Guo Y, Wei D, Xu S et al. · 2026 · Risk analysis : an official publication of the Society for Risk Analysis
This study examines the potential of comics as an infotainment strategy for engaging the public in climate change mitigation from the perspective of the situational theory of public. A 2 × 2 × 2 factorial experiment (N = 320) was conducted…
View details →Negative / Null Result ReportMedicine
Barton R, Van Den Helm S, Yaw HP et al. · 2026 · Transfusion
Study question To describe the blood product utilization during neonatal and pediatric extracorporeal membrane oxygenation (ECMO) and to determine whether its usage correlates with clinical outcomes of bleeding, thrombosis or mortality.…
View details →Failed Experiment ReportMedicine
Afuh R, Ashinze P, Banerjee S et al. · 2026 · Discover oncology
Melanoma remains one of the most aggressive cutaneous malignancies, accounting for a disproportionate share of skin cancer-related mortality despite relatively lower incidence. Over the past decade, immune checkpoint inhibitors (ICIs) have…
View details →Failed Experiment ReportMedicine
Mourtzos MA, Patoulias D, Keklikoglou NM et al. · 2026 · Diabetes research and clinical practice
Neurodegenerative diseases (NDs) are increasingly recognized as multifactorial disorders in which neurometabolic dysfunction intersects with classic pathological processes, including protein misfolding, neuroinflammation, synaptic failure…
View details →Negative / Null Result ReportMedicine
Liu JY, Scumpia P, Ni C et al. · 2026 · Dermatology online journal
A 77-year-old woman presented with pruritic, scaly, erythematous papules and plaques on the face, which subsequently spread to the trunk. Over nearly 2 years, 5 skin biopsies were performed, consistently suggesting a subacute to chronic…
View details →Negative / Null Result ReportMedicine
Promer K, Brenner SB, Ostrer L et al. · 2026 · Current opinion in HIV and AIDS
Purpose of review This article reviews the evidence behind mpox antiviral therapies which are clinically available and/or or under clinical investigation. For much of the mpox epidemic, tecovirimat has been used compassionately but there…
View details →Negative / Null Result Report
Lehrer S · 2025 · Preprint
Abstract Background Monoclonal antibodies targeting pathological tau have repeatedly failed in Alzheimer’s disease (AD) clinical trials. Whether plasma phosphorylated tau (pTau) exhibits dynamic progression or cognitive relevance in…
View details →Negative / Null Result ReportMedicine
Weirauch T, Yahav D, Zahavi I et al. · 2026 · Infection
The escalating global threat of antimicrobial resistance represents a critical challenge for contemporary medicine. Intestinal colonization by multidrug-resistant organisms (MDROs) is increasingly identified as a primary driver of…
View details →Negative / Null Result ReportMedicine
Kirkiz Kayalı S, Deveci TS, Gülbahar Ö et al. · 2026 · Transplantation proceedings
Introduction Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative treatment for hematologic disorders. Acute graft-versus-host disease (aGVHD) remains a major cause of nonrelapse mortality. Distinguishing aGVHD from…
View details →Negative / Null Result Report
Ferreira AV, Dias M, Silva PA et al. · 2026 · Preprint
Abstract Background Brain tissue oxygen pressure (PbtO₂) monitoring is increasingly used in neurocritical care, but whether PbtO₂ provides complementary information beyond conventional parameters such as intracranial pressure (ICP) and…
View details →Negative / Null Result Report
Zhao Y, Zhao Q, Yu X et al. · 2026 · Preprint
Abstract Learning behavior is an important acquired behavior in fish, and the capacity for learning and memory plays a crucial role in foraging or anti-predator behavior. In this study, we selected the juveniles of S. schlegelii as the…
View details →Negative / Null Result Report
Sun Al, Liu ZH, Li L et al. · 2026 · Preprint
Abstract Background To measure the eyelid margin width and the distance between the eyelash gray lines in Han Chinese children, providing data for pediatric ocular anthropometry. Methods This prospective, single-center, observational study…
View details →Negative / Null Result ReportMedicine
Patel J, Patil S · 2026 · Journal of bodywork and movement therapies
Background Stroke survivors exhibit gait inefficiencies with increased energy expenditure, potentially linked to kinematic deficits. This exploratory study examined whether peak sagittal joint angles predict Energy Expenditure Index (EEI)…
View details →Negative / Null Result ReportMedicine
Keskin E · 2026 · Journal of health psychology
This cross-sectional descriptive study investigated the association between caffeine consumption and anxiety and depression among Turkish university students, a population experiencing high academic stress and widespread caffeine use. A…
View details →Failed Experiment ReportOpen accessMedicine
Çimen Ş, Altındağ N, Erginöz E et al. · 2026 · International journal of molecular sciences
The relationship between biochemical severity parameters and adenoma burden in primary hyperparathyroidism (PHPT) has been widely studied, although some variability across studies persists. This relationship is clinically relevant for…
View details →Negative / Null Result ReportMedicine
Steiger, Almeida, Massini et al. · 2026 · Journal of functional morphology and kinesiology
Objectives: This study aimed to compare the acute effects of high-intensity resistance training (HIRT), low-intensity resistance training (LIRT), and low-intensity resistance training with blood flow restriction (LIRT-BFR) on heart rate…
View details →Negative / Null Result ReportMedicine
Trovato, La Marca, Simonini et al. · 2026 · Journal of personalized medicine
Background/Objectives: The Systemic Immune-Inflammation Index (SII), derived from routine blood counts, has emerged as a potential marker of systemic inflammation in psoriasis. However, its longitudinal behavior across different systemic…
View details →Negative / Null Result ReportMedicine
Biancari, Dell'Aquila, Mäkikallio et al. · 2026 · Journal of cardiovascular development and disease
Background: The nature and prognosis of type A intramural hematoma (TAIMH) are not well established. In this study, we evaluated the early and late outcome after surgery for this emergency condition. Methods: The ERTAAD registry included…
View details →Negative / Null Result ReportMedicine
Aslan, Sural, Özçalışkan et al. · 2026 · Journal of cardiovascular development and disease
Total coronary revascularization via anterior thoracotomy (TCRAT) enables complete anatomical revascularization without sternotomy; however, data on its impact on left ventricular function remain limited. This study compared left…
View details →Negative / Null Result ReportMedicine
Han, Yoo, Kang et al. · 2026 · Diseases (Basel, Switzerland)
Psoriasis is a chronic systemic inflammatory disease associated with increased cancer risk; however, its relationship with colorectal cancer (CRC) remains unclear. This question is particularly relevant in Asia, where CRC incidence has…
View details →Failed Experiment ReportMedicine
Knapper, Thomas, Hills et al. · 2026 · Blood
We assessed the addition of the tyrosine kinase inhibitor Quizartinib, following intensive chemotherapy and as maintenance, in patients aged >60 years with AML or high-risk MDS, regardless of FLT3 mutation status. 463 patients (median age…
View details →Negative / Null Result ReportMedicine
Rosso, Fico, Di Criscio et al. · 2026 · Frontiers in immunology
The diagnosis of Sjögren's Disease (SjD) remains challenging due to the non-specific nature of sicca symptoms and the need for invasive biopsies. This pilot study aimed to investigate the potential of salivary Substance P (SP), a…
View details →Negative / Null Result ReportMedicine
Yokogawa, Yoon, Lee et al. · 2026 · Cureus
Background and objective It remains unclear whether atlas hypoplasia is causative of symptomatic cervical canal stenosis or represents an independent and unrelated finding. There have been few dedicated studies describing atlas hypoplasia,…
View details →Negative / Null Result ReportMedicine
Mahajan, Akhtar, Sharma et al. · 2026 · Asian journal of transfusion science
Due to rapid technological advancements, several new methods such as telephone (TP), e-mail, social media, WhatsApp (WA), and Short Message Services are being used as effectively among blood centers worldwide for postdonation communication…
View details →Negative / Null Result ReportMedicine
Chen, Spadaccini, Sahai et al. · 2026 · Endoscopy international open
Endoscopic ultrasound-guided choledochoduodenostomy using a lumen-apposing metal stent (EUS-CDSL) has been shown in randomized controlled trials (RCTs) to be effective compared with endoscopic retrograde cholangiopancreatography (ERCP) in…
View details →Failed Experiment ReportMedicine
Ren, Nan, Li et al. · 2026 · Annals of medicine
To evaluate the analgesic efficacy of thoracic paravertebral block (TPVB) with different doses of liposomal bupivacaine (LB) or ropivacaine in patients undergoing single-port thoracoscopic lung surgery. A total of 105 patients scheduled…
View details →Failed Experiment ReportMedicine
Gauci, Millet, Jacquot et al. · 2026 · Journal of shoulder and elbow surgery
The efficacy of patient-specific guides (PSGs) in improving accuracy and reducing the number of outliers in glenoid implant positioning in anatomic total shoulder arthroplasty has been clearly shown. However, long-term clinical benefit in…
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