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Browse the failure-mode index

21,707 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen access

Comparison of the Effect of Eight Week Training Program Schedule With Two Different Stretching Patterns Strengthening on Changes in the Status of Lower Cross Syndrome

Chiman َ Alyarnezhad, Ali Shams Majalan · 2021 · Journal of Sport Biomechanics

Objective: Different timing of performing stretching and strengthening exercises can have different effects on the condition of Lower Crossed Syndrome (LCS). This study aims to compare the effects of eight-week training using stretching…

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Negative / Null Result ReportMedicine

Is There Postoperative Fluid Accumulation After the Unilateral Biportal Endoscopic Technique as Minimally Invasive Spine Surgery: In Vivo Study.

Omer Bozduman, Kadri Yıldız, Bilal Aykaç et al. · 2025 · Turkish Neurosurgery

AIM To establish the presence and amount of fluid accumulation in UBE procedure, and the relationship of fluid management with other variables. MATERIAL AND METHODS All patients underwent UBE spinal surgery with one level between September…

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Negative / Null Result ReportOpen accessMedicine

The effectiveness of generic emails versus a remote knowledge broker to integrate mood management into a smoking cessation programme in team-based primary care: a cluster randomised trial

N. Minian, Sheleza Ahad, Anna Ivanova et al. · 2021 · Implementation Science

Background Knowledge brokering is a knowledge translation approach that has been gaining popularity in Canada although the effectiveness is unknown. This study evaluated the effectiveness of generalised, exclusively email-based prompts…

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Failed Experiment ReportOpen access

Growth Performance of Crossbred Goat (Beetal ×Assam Local) by Feeding Cultivated Fodder under Intensive Farming

L. D. Singha, G. Saikia, B. Saikia et al. · 2022 · International Journal of Current Microbiology and Applied Sciences

The small ruminant husbandry sector in India is not an organized sector like poultry, however, now-a- days many young entrepreneurs are setting up goat units using scientific rearing practices, because small ruminants play an important…

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Negative / Null Result ReportOpen accessMedicine

Effect of isolated and combined ingestion of caffeine and citrulline malate on resistance exercise and jumping performance: a randomized double-blind placebo-controlled crossover study

M. Haugen, F. T. Vårvik, J. Grgic et al. · 2023 · European Journal of Nutrition

The aim of this study was to explore the isolated and combined effects of caffeine and citrulline malate (CitMal) on jumping performance, muscular strength, muscular endurance, and pain perception in resistance-trained participants. Using…

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Negative / Null Result ReportMedicine

The Effect of Pomegranate Extract on Survival and Peritoneal Bacterial Load in Cecal Ligation and Perforation Model of Sepsis in Rats

S. Tavasoli, A. Zarnani, Mohamadreza Vafa et al. · 2014 · International Journal of Preventive Medicine

Background: Sepsis is one of the major causes of death in intensive care units. Oxidative stress and hyper-inflammation has been shown to be major cause of mortality and morbidity in septic cases. Pomegranate is a fruit considered for its…

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Negative / Null Result ReportOpen accessMedicine

Influence of Gold Nanoparticle Incorporation Into Glass Ionomer Cement on Fibroblast Metabolic Activity, Surface Roughness and Hardness.

Zia A, Baldwin A, Nlemorisa C et al. · 2026 · International journal of dentistry

Objective To assess the influence of gold nanoparticle (AuNP) liquid-phase modification of glass ionomer cement (GIC) on fibroblast metabolic activity, alongside its effects on surface hardness and roughness, in an exploratory pilot in…

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Negative / Null Result ReportOpen accessMedicine

Structure-Driven Bioactivity of Chitosan-Agarose-Gelatin Hydrogels Functionalized with Tannic Acid-Cu<sup>2+</sup>/Sr<sup>2+</sup> Complexes.

Wekwejt M, Chevallier P, Desgagne F et al. · 2026 · ACS applied materials & interfaces

Hydrogels represent a versatile platform for regenerative applications; nevertheless, their translation is often limited by insufficient biofunctionality and poorly defined structure-property relationships in multicomponent networks. In…

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Negative / Null Result ReportMedicine

A 2 year retrospective study of vegan patients and their pregnancy outcomes in a tertiary level Irish hospital.

Abdelrahman M, Maher S, Lindow SW et al. · 2026 · International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

Objective Recent previous studies have revealed outcomes of higher risk of low birth weight, small for gestational age, and pre-eclampsia for vegan pregnant women compared to other diets. This review examined if patients with vegan diet in…

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Negative / Null Result Report

A Comparative Study on the Effects of Spherical and Aspheric Orthokeratology Lenses on Myopia Control and Ocular Surface Health in Adolescents: A Retrospective Cohort Study Based on Propensity Score Matching

Cai¹ J, Lan² G, Lin² Y et al. · 2026 · Preprint

Abstract Purpose To compare the 1-year efficacy of spherical versus aspheric base curve orthokeratology (OK) lenses in controlling axial length (AL) elongation in myopic adolescents, and to explore differences in their impact on tear film…

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Negative / Null Result ReportOpen accessMedicine

Does Combined Intravenous and Topical Tranexamic Acid Offer Additional Benefit Compared With Intravenous or Topical Alone in Open Elbow Arthrolysis-A Pilot Randomized Controlled Trial.

Chen C, Zhang J, Hua K et al. · 2026 · Orthopaedic surgery

Purposes Open elbow arthrolysis (OEA) is a common method for treating post-traumatic elbow stiffness, which may lead to severe bleeding when resecting heterotopic ossification (HO) and fibrous scar tissue. The purpose of this study is to…

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Negative / Null Result ReportMedicine

The influence of lesion type and lesion location on the prediction of language laterality in patients with cerebral vascular malformations using functional MRI.

Rossmann J, Hense K, Knott M et al. · 2026 · Journal of neurosurgery

Objective Predicting language lateralization using functional MRI (fMRI) in patients with cerebral vascular malformations close to language areas is essential for treatment decision-making and patient outcomes. Functional MRI-based…

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Negative / Null Result ReportOpen accessMedicine

Comparable improvements in selective, but not sustained, attention in response to a multi-ingredient nootropic formulation when compared with caffeine.

Hearris MA, Langan-Evans C, Foo WL et al. · 2026 · European journal of nutrition

PURPOSE: The ergogenic effects of caffeine on cognitive performance are largely restricted to improved alertness and enhanced attention and do not typically extend to other cognitive domains. In contrast, plant extracts and phytochemicals…

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Negative / Null Result ReportMedicine

Retrospective Analysis of Dronedarone Versus Amiodarone on Outcomes Following Radiofrequency Ablation for Atrial Fibrillation.

Shi Y, Shi X, Li H et al. · 2026 · British journal of hospital medicine (London, England : 2005)

Aims/background Pharmacological therapy can enhance the therapeutic efficacy of radiofrequency ablation (RFA) for atrial fibrillation (AF) and reduce the risk of recurrence. Dronedarone and amiodarone are two commonly prescribed adjuvant…

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Negative / Null Result ReportMedicine

Similar water uptake depths in lianas and trees, but divergent functional trait coordination across organs in a seasonally dry tropical forest in Cambodia.

Hiiragi K, Sopheak T, Sophors C et al. · 2026 · Tree physiology

Although previous studies have suggested that lianas exhibit superior growth compared with trees during dry seasons, their strategies for acquiring water remain poorly understood. This study investigated the water uptake depth and…

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