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Browse the failure-mode index

21,257 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result Report

Heparinized venous blood gas syringes are associated with a significant decrease in measured packed cell volume in dogs due to hemodilution

Coyne M. Hopey, Dana Caldwell, Erin Binagia et al. · 2025 · Journal of the American Veterinary Medical Association

Abstract OBJECTIVE To assess the effect of hemodilution on PCV when commercial preheparinized venous blood gas (PH-VBG) syringes are used compared to directly filled Hct tubes, and to evaluate the impact of delayed centrifugation on PCV.…

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Negative / Null Result Report

Allergies, asthma treatment, and eviction diet have a significant impact on the respiratory effort during sleep and the apnea-hypopnea index in children with obstructive sleep apnea-obesity/asthma association: A STROBE-compliant study

Kalomoira Kefala, Philippe Guerin · 2026 · Medicine

The pathophysiological mechanisms implicated in obstructive sleep apnea (OSA) associated with asthma/allergies remain unclear. Apnea-hypopnea index (AHI) alone is insufficient to accurately guide adequate treatment without identifying the…

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Negative / Null Result Report

Association of Dyslipidemia with Clinically Significant Macular Edema (CSME) in Type – II Diabetes Mellitus

Md. Mufakh Kharul Islam, Md. Mizanur Rahman, Md. Khalid Hossain et al. · 2022 · Scholars Journal of Applied Medical Sciences

Aim: To observe the association between dyslipidemia and CSME in Type – II diabetes mellitus. Method: With convenience type of sampling technique 36 patients of diabetic retinopathy (DR) with CSME (Group–I) and another 35 patients of DR…

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Negative / Null Result Report

Single nucleotide polymorphism of the promotor region of Interleukin-10 gene did not show significant association with spontaneous clearance of hepatitis C virus infection in Egyptian patients

Fatma Waly, Maysaa El Sayed Zaki, Hany Shabana et al. · 2023 · Gastroenterology & Hepatology: Open Access

Introduction: Accurate etiologies of spontaneous clearance of HCV infection are hard to be clarified. However, it is proposed that genetically determined interleukin-10 (IL-10) changes play an important function in HCV elimination.…

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Negative / Null Result Report

CT Radiomics Models Did Not Outperform Experts in Predicting [68Ga]Ga-PSMA-PET Positivity in Prostate Cancer Lymph Node Staging

Thula Cannon Walter-Rittel, Boris Gorodetski, Alexander Hartenstein et al. · 2026 · Current Oncology

Background: The use of [68Ga]Ga-PSMA-PET/CT for prostate cancer (PCa) staging is limited by cost and availability. This study evaluates whether radiomic features from contrast-enhanced (CE) CT can predict PSMA-positive lymph nodes (LNs) as…

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Negative / Null Result Report

Cyber defence automation: Can AI outperform hackers?

Vitalii Yasenenko · 2025 · Technologies and Engineering

Growing cyber threats in the context of digital transformation require improved methods of automating cyber defence, in particular, through the use of artificial intelligence to detect and respond to attacks. The purpose of the study was…

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Negative / Null Result Report

Can Artificial Intelligence Outperform Humans in ETF Management?

Sahana Ganesan · 2024 · Journal of Student Research

‘Exchange Traded Funds’ (ETFs) are basket/bundle funds consisting of a portfolio of stock assets from multiple companies and organizations, traded similar to normal stocks. ETFs help with diversification of the investment, risk management…

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Negative / Null Result Report

Human therapists outperform AI therapists in delivering CBT

Valerie A. Canady · 2025 · Mental Health Weekly

An AI therapist cannot replicate the nuanced empathy and therapeutic alliance of human therapists when delivering cognitive behavioral therapy (CBT), concluded researchers of a new study presented during the American Psychiatric…

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Negative / Null Result Report

(Un)Sustainable Development: Do Democracies Outperform Autocracies?

Leonel Prieto, Arman Canatay, Muhammad R. Amin · 2025 · Sustainable Development

ABSTRACT Political regimes significantly determine the ability of nations to develop in one way or another. The current crisis of democracy has prompted the following question: to what degree does democracy deliver? To answer this…

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Negative / Null Result Report

A Baldrige Portfolio: Does Quality Outperform The Market?

John A. Helmuth, Hei-Wai Lee · 2011 · International Business & Economics Research Journal (IBER)

This paper investigates the claim, by the Department of Commerce, that a portfolio of Baldrige National Quality Award winners outperforms the market. They find that there is a 92 percent return for Baldrige winners as compared to a 33…

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