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WASTE Journal

Browse the failure-mode index

21,253 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Effect of crossword puzzle on nursing students' willingness to work with older adults and gerontological nursing competence: A waiting list randomized controlled trial.

Erdoğan, Ayaz-Alkaya · 2026 · Nurse education in practice

To evaluate the effect of crossword puzzle activities on nursing students' willingness to work with older adults and their competence in gerontological nursing. Although crossword puzzles are widely used learning tools, their effects in…

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Negative / Null Result ReportMedicine

Effects of Diet Composition and Yeast Cell Wall Supplementation on Ruminal Fermentation, Gas Kinetics, Methane Production and Digestibility Assessed In Vitro Using Gas Production and Daisy II Incubator Systems.

Ramay, Bundur, Riaz et al. · 2026 · Veterinary medicine and science

Optimizing ruminant diets and mitigating methane emissions using feed additives like yeast cell wall is of growing significance in animal nutrition. The present study aimed to evaluate the effects of varying roughage-to-concentrate (R:C)…

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Negative / Null Result ReportMedicine

Plasma chaperone-mediated autophagy associated protein HSPA8 combined with white matter hyperintensities serves as the predictive marker of early-stage Alzheimer's disease.

Yan, Liang, Zhou et al. · 2026 · Frontiers in aging neuroscience

The relationship between plasma chaperone-related autophagy proteins and white matter hyperintensity (WMH) in Alzheimer's disease (AD) remains unclear. We employed 4D-DIA proteomics to identify plasma protein changes, and evaluated the…

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Negative / Null Result ReportMedicine

Synergistic Effects of IMP-1700, Ciprofloxacin, and X-Ray Radiation in Bacteria and Mammalian Cell Lines: Implications for Use in Antimicrobial-Resistant Bacteria.

Andersen, Sloth, Bøgestad et al. · 2026 · MicrobiologyOpen

IMP-1700 was developed as a compound designed to target bacterial DNA repair-associated pathways, including homologous recombination mediated by the AddAB/RecBCD system. While its antibacterial properties are well established, the…

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Negative / Null Result ReportMedicine

Seasonal Drought Reduces Carbon Sequestration in Coastal Wetlands.

Jia, Han, Macreadie et al. · 2026 · Global change biology

Coastal wetlands represent one of the most intensive carbon sinks, and the stability of their soil carbon reserves is critical to the global carbon balance. While existing studies have predominantly focused on the effects of changes in…

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Negative / Null Result ReportMedicine

Comorbidity Burden and Length of Stay After Myocardial Infarction: A Retrospective Study Using Large Language Model-Assisted Chart Abstraction in a Tertiary Cardiac Hospital.

Lim, Chin, Chee et al. · 2026 · The American journal of cardiology

Patients' length of stay (LOS) during admission for myocardial infarction (MI) represents a closely tracked outcome metric for Cardiology services, which has declined over time. Charlson Comorbidity Index (CCI) is a validated tool for…

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Negative / Null Result ReportMedicine

Hypolipidemics reduce the rate of Alzheimer's disease development and dementia progression: A cohort study linked with genetic and neuropathological analyses.

Sternberg, Podolsky, Yu et al. · 2026 · The journal of prevention of Alzheimer's disease

High cholesterol contributes to the development and progression of dementia due to both Alzheimer's disease (A.D.) and vascular pathology. However, the effects of lipid-lowering regimen (LLR) on cognitive dysfunction and brain…

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Negative / Null Result ReportMedicine

Effects of sex, residential area, and age on the seasonality of insomnia-related symptoms: a detailed re-analysis of the longitudinal data of Japanese community residents.

Kizuki, Kaneko, Taniguchi et al. · 2026 · Sleep and biological rhythms

We previously found that seasonal changes in sleep duration were affected by sex, residential area, and age in Japanese community residents. This study aimed to determine whether these factors also affect the seasonality of…

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Negative / Null Result ReportMedicine

Treatment of Persisting Symptoms after Concussion with Repetitive Transcranial Magnetic Stimulation: A Double-Blinded, Randomized, Controlled Trial.

Campbell, Wilson, Du Plessis et al. · 2026 · Journal of neurotrauma

Following a mild traumatic brain injury (mTBI), up to 30% of individuals will experience persisting symptoms beyond 3 months. Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive neuromodulation technique that has shown…

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Negative / Null Result ReportMedicine

Opioid Toxicity Following Concomitant Use of Macrolide Antibiotics with Fentanyl, Hydromorphone, or Oxycodone: A Population-Based Study.

Antoniou, Yang, Juurlink et al. · 2026 · Clinical pharmacology and therapeutics

Fentanyl, hydromorphone, and oxycodone are metabolized by cytochrome P450 3A4 (CYP3A4). Co-administration with CYP3A4-inhibiting macrolides (clarithromycin or erythromycin) may increase opioid concentrations and overdose risk, but the…

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Negative / Null Result ReportMedicine

Cerebellar Volumes Are Smaller in Veterans with PTSD and a History of Mild Traumatic Brain Injury, but Not Mild Traumatic Brain Injury Alone.

Huggins, Martinez, Baird et al. · 2026 · Journal of neurotrauma

Mild traumatic brain injury (mTBI), a common health burden among combat veterans, has been associated with alterations in brain structure. Moreover, post-traumatic stress disorder (PTSD), frequently comorbid with mTBI, is linked to smaller…

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Negative / Null Result ReportMedicine

Microbial-chemical synergy in the immobilization of cadmium in contaminated floodplain soils: A field-mesocosm assessment of Sporosarcina pasteurii and SiO₂ nanoparticles.

Han, Wang, Shang et al. · 2026 · Journal of hazardous materials

Cadmium (Cd) accumulation in river floodplains is threatening grain safety and agro-ecosystem sustainability. We conducted a 10-month field-mesocosm experiment to evaluate the effectiveness, side effects and underlying mechanisms of three…

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