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Browse the failure-mode index

21,252 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result Report

#4204 MULTIPARAMETRIC MAGNETIC RESONANCE IMAGING BIOMARKERS OUTPERFORM LAB BIOMARKERS FOR PREDICTING PROGRESSION OF DIABETIC KIDNEY DISEASE

Paul Hockings, Kianoush Makvandi, Johannes Hulthe et al. · 2023 · Nephrology Dialysis Transplantation

Abstract Background and Aims We recently showed that comprehensive non-contrast multiparametric Magnetic Resonance Imaging (mpMRI) allowed functional and structural assessment of diabetic kidney disease (DKD) and that an imaging endpoint,…

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Negative / Null Result Report

Assessing the Performance of 8 AI Chatbots in Bibliographic Reference Retrieval: Grok and DeepSeek Outperform ChatGPT, but None are Entirely Accurate

Álvaro Cabezas-Clavijo, Pavel Sidorenko-Bautista · 2026 · Journal of Data and Information Science

Abstract Purpose This study evaluates the reliability of eight generative artificial intelligence chatbots—including ChatGPT, Claude, Gemini, and DeepSeek—when functioning as autonomous agents for academic bibliographic generation,…

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Negative / Null Result Report

Molecular Diagnostic Techniques Used to Confirm an Unusual Case of BAPoma

Aaron Atkinson, Konstantinos Linos, Shaofeng Yan et al. · 2017 · The FASEB Journal

Study Objective BAP1 (BRCA1‐associated protein 1) is a critical tumor suppressor that promotes genome stability and DNA damage response, in addition to other cellular processes. BAP1 maps to 3p21 and is a nuclear localized deubiquitinating…

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Negative / Null Result Report

261 LENGTH OF HOSPITAL STAY AND THE ASSOCIATION WITH READMISSION AFTER UNCOMPLICATED ESOPHAGECTOMY. SIGNIFICANT HOSPITAL VARIATION IN THE NETHERLANDS.

D Voeten, L Werf, J Sandick et al. · 2020 · Diseases of the Esophagus

Abstract Prolonged length of hospital stay is a negative outcome of esophageal cancer surgery, not only for the patient; it also leads to increased hospital costs. Within the scope of value-based health care, this study aimed to analyze…

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Negative / Null Result Report

The Effect of Income on Daily Physical Activity Levels in Americans

Jacob Foster, null null, null null et al. · 2023 · John Heinrichs Scholarly & Creative Activities Day

I analyze the relationship between income range and exercise level. The data that I have selected for this project was obtained from the Health Information National Trends Survey website. The specific question that the respondents were…

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Negative / Null Result Report

Detection of clinically significant prostate cancer by micro-ultrasound-informed systematic biopsy during MRI/micro-ultrasound fusion biopsy

Betty Wang, Stacey Broomfield, Anaïs Medina Martín et al. · 2022 · Canadian Urological Association Journal

Introduction: High-resolution micro-ultrasound (microUS) is a novel imaging technique that may visualize clinically significant prostate cancer (csPCa), including those missed by magnetic resonance imaging (MRI), in real-time during…

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Negative / Null Result Report

Humans Outperform Machines at the Bilingual Shannon Game

Marjan Ghazvininejad, Kevin Knight · 2016 · Entropy

We provide an upper bound for the amount of information a human translator adds to an original text, i.e., how many bits of information we need to store a translation, given the original. We do this by creating a Bilingual Shannon Game…

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Negative / Null Result Report

An impedance threshold device did not improve carotid blood flow in a porcine model of prolonged cardiac arrest

Benedict Kjaergaard, Hans O. Holdgaard, Sigridur O. Magnusdottir et al. · 2020 · Journal of Translational Medicine

Abstract Background An impedance threshold device (ITD) was developed to increase venous return to the heart and therefore increase cardiac output and organ blood flow during cardiopulmonary rescue (CPR). Basic CPR aims to maintain…

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Negative / Null Result Report

A novel approach to off-clamp partial nephrectomy demonstrates significant improvements in renal injury in an experimental porcine model

Daniel Olvera-Posada, Shouzhe Lin, Ghaleb Aboalsamh et al. · 2017 · Canadian Urological Association Journal

Introduction: We sought to design a partial nephrectomy (PN) with contralateral total nephrectomy porcine model and assess the underlying mechanisms of ischemia reperfusion injury (IRI) after PN using a novel, clinically approved resection…

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Negative / Null Result Report

Type III collagen formation is significantly associated with risk of outcome in HFpEF patients but loses its significant association with underlying AF

E Angeli, A Reese-Petersen, A Gonzalez et al. · 2022 · European Heart Journal

Abstract Introduction Heart failure with preserved ejection fraction (HFpEF) is the most common type of heart failure, associated with high morbidity and mortality. Atrial fibrillation (AF) has been associated with structural remodelling…

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Negative / Null Result Report

Granuloma Annulare, Autoimmune Thyroiditis, and Lichen Sclerosus in a Woman: Randomness or Significant Association?

Mariele De Paola, Anastasia Batsikosta, Luca Feci et al. · 2013 · Case Reports in Dermatological Medicine

We report a 60-year-old Caucasian female with a 2-year history of diffused granuloma annulare (GA), who presented for the simultaneous occurrence of genital lichen sclerosus (LS) and autoimmune thyroiditis (AT). In our opinion this…

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Negative / Null Result Report

Patient leaflets on respiratory tract infections did not improve shared decision making and antibiotic prescriptions in a low-prescriber setting

Andreas Plate, Stefania Di Gangi, Christian Garzoni et al. · 2024 · Scientific Reports

Abstract Patient information leaflets can reduce antibiotic prescription rates by improving knowledge and encouraging shared decision making (SDM) in patients with respiratory tract infections (RTI). The effect of these interventions in…

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Negative / Null Result Report

The specific leaf area of forest species subjected to different degrees of shading did not differ when detached and full leaflets were compared

Jacqueline Lucia Guimarães, Cristina Moll Hüther, Ramonn Diego Barros de Almeida et al. · 2020 · Semina: Ciências Agrárias

Studies of forest species under different environmental conditions are essential for enhancing our understanding of plant-environment relationships. Different light conditions interfere with the production of seedlings within forests, and…

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Negative / Null Result Report

Study: The Lack of Significant Association of the Catechol‐ O ‐Methyl Transferase (COMT) Gene Polymorphism in Violent Offenders with Mental Retardation

Aysun Baransel Isir, Alper Ibrahim Dai, Muradiye Nacak et al. · 2010 · Journal of Forensic Sciences

Abstract: Little is known about criminality of cognitively impaired people and also there have been no reports on the relationship between catechol‐ O ‐methyl transferase (COMT) and committed Mental Retardation (MR) subjects. In the…

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