Negative / Null Result Report
Kostas Iakovou, Kleopatra Schulpis · 2019 · International Journal of Adolescent Medicine and Health
Abstract Introduction Classical Phenylketonuria (PKU) is a metabolic disease characterized by high phenylalanine (phe) levels in blood and brain. PKU patients are commonly treated with low phe diet supplemented with amino acid free…
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Omar N. A. Demerdash, Amanda Buyan, Julie C Mitchell · 2010 · Proteins: Structure, Function, and Bioinformatics
Abstract We present a computationally efficient method for flexible refinement of docking predictions that reflects observed motions within a protein's structural class. Using structural homologs, we derive deformation models that capture…
View details →Negative / Null Result Report
Tania Ionin, Maria Goldshtein, Tatiana Luchkina et al. · 2021 · Linguistic Approaches to Bilingualism
Abstract This paper reports on an experimental investigation of what second language (L2) learners and heritage speakers of Russian know about the relationship between word order and information structure in Russian. The participants…
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Thomas Popp, Jonathan Mittaz · 2022 · Remote Sensing
The AVHRR aerosol optical depth (AOD) is inverted from measured reflectances in the red band using a statistical correlation of surface reflectance with mid-infrared channel reflectances and a modelling climatology of the aerosol type. For…
View details →Negative / Null Result Report
Craig R. Miller, Anna C. Nagel, LuAnn Scott et al. · 2016 · PeerJ
Parallelism is important because it reveals how inherently stochastic adaptation is. Even as we come to better understand evolutionary forces, stochasticity limits how well we can predict evolutionary outcomes. Here we sought to quantify…
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Tianxing Pang, Jianping Peng, Ruiling Bian et al. · 2022 · Biology
RNA silencing is a host innate antiviral mechanism which acts via the synthesis of viral-derived small interfering RNAs (vsiRNAs). We have previously reported the infection of phytopathogenic fungi by plant viruses such as cucumber mosaic…
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Naoko Witzel · 2019 · Quarterly Journal of Experimental Psychology
This study examines whether synonyms are represented similarly to translation equivalents in the bilingual mind. In particular, this study investigated whether there is masked synonym priming such that it will simulate masked translation…
View details →Failed Experiment Report
Mark W. Lowdell, Ben Weil · 2023 · Frontiers in Immunology
Unlike conventional pharmaceuticals, biologics and Advanced Therapy Medicinal Products (ATMPs) are required to meet a standard of “potency” as part of the final release criteria at completion of manufacture. During early phase clinical…
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Bukola Usidame, Gang Meng, James F Thrasher et al. · 2022 · Nicotine & Tobacco Research
Abstract Introduction Using a quasiexperimental design, we compared the impact of the 2000 Canadian introduction of graphic warning labels (GWLs) on differences in smoking prevalence by sex and education, to the United States, where no…
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Cory J. Clark, Paul Connor, Calvin Isch · 2023 · Proceedings of the National Academy of Sciences
With a sample of 228 psychology papers that failed to replicate, we tested whether the trajectory of citation patterns changes following the publication of a failure to replicate. Across models, we found consistent evidence that failing to…
View details →Failed Experiment Report
B. V. Senthil Kumar, Khalifa Al-Shaqsi, Hemen Dutta · 2020 · Advances in Difference Equations
Abstract The aim of this present article is to investigate various classical stability results of the multiplicative inverse difference and adjoint functional equations $$ m_{d} \biggl(\frac{rs}{r+s} \biggr)-m_{d} \biggl( \frac{2rs}{r+s}…
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Eijun Sueyoshi, Tomonori Murakami, Xi He et al. · 2022 · Medicine
Abstract The differences between the pathologies of cases of type A acute aortic dissection (AAD) that did and did not result in prehospital death (PHD) have not been fully elucidated. This study aimed to compare the CT findings and…
View details →Abandoned Hypothesis
Frederick CHOO, Esther GOH · 2019 · International Journal of Theology, Philosophy and Science
Alvin Plantinga has famously responded to the logical problem of evil by appealing to the intrinsic value of significant free will. A problem, however, arises because traditional theists believe that both God and the redeemed who go to…
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Natalie L. Phillips, Elysa Widjaja, Mary Lou Smith · 2020 · Epilepsia
Abstract Objective To evaluate longitudinal changes in caregiver depression, anxiety, and family relationships following resective surgery for pediatric drug‐resistant epilepsy (DRE). Methods This multicenter cohort study involved 177…
View details →Negative / Null Result Report
Stephen Kidd · 2020 · Apeiron
Abstract The emergence of mathematical probability has something to do with dice games: all the early discussions (Cardano, Galileo, Pascal) suggest as much. Although this has long been recognized, the problem is that gambling at dice has…
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Sumit Kumar Ram, Shyam Nandan, Didier Sornette · 2022 · Scientific Reports
Abstract We investigate the predictability and persistence of individual and team performance (hot-hand effect) by analyzing the complete recorded history of international cricket. We introduce an original temporal representation of…
View details →Failed Experiment Report
Jay A. Johnson, Nicolai B. Mortensen, Christopher J. Gibson et al. · 2014 · Annals of Glaciology
Abstract Drilling the WDC06A borehole at the West Antarctic Ice Sheet (WAIS) Divide with the Deep Ice Sheet Coring (DISC) drill began in December 2007 and was successfully completed in December 2011 to a depth of 3405 m. The design and…
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Alexander A. Kutepov, Ladislav Rezac, Artem G. Feofilov · 2017 · Atmospheric Measurement Techniques
Abstract. Since January 2004, the planetary Fourier spectrometer (PFS) on board the Mars Express satellite has been recording near-infrared limb spectra of high quality up to the tangent altitudes ≈ 150 km, with potential information on…
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Peter Baas, Jennifer D. Knoepp, Jacqueline E. Mohan · 2019 · Forests
Understanding the dominant soil nitrogen (N) cycling processes in southern Appalachian forests is crucial for predicting ecosystem responses to changing N deposition and climate. The role of anaerobic nitrogen cycling processes in…
View details →Negative / Null Result Report
Michelle McDonald · 2023 · Frontiers in Nephrology
The role of allograft nephrectomy (AN) in failed renal transplants is a topic of debate, owing to controversial results reported in the literature and the fact that most of the studies are limited by a retrospective design and small…
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Karin Kvale, Wolfgang Koeve, Nadine Mengis · 2021 · Frontiers in Marine Science
The impact of calcifying phytoplankton on atmospheric CO 2 concentration is determined by a number of factors, including their degree of ecological success as well as the buffering capacity of the ocean/marine sediment system. The relative…
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Hossein Ghalenavi, Saeid Norouzi-Apourvari, Mahin Schaffie et al. · 2019 · Journal of Petroleum Exploration and Production Technology
Abstract In reservoir simulation, the fluid composition is usually assumed uniform for the whole reservoir, while in many reservoirs, oil and gas composition changes with depth. This phenomenon which is known as compositional grading could…
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Daichi Tsuna · 2021 · Publications of the Astronomical Society of Japan
Abstract In a failed supernova, partial ejection of the progenitor’s outer envelope can occur due to weakening of the core’s gravity by neutrino emission in the protoneutron star phase. We consider emission when this ejecta sweeps up the…
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Huihui Liu, Yan-Song Gao, Xiang-Jun Chen et al. · 2016 · Scientific Reports
Abstract Creatine kinase (CK) helps maintain homeostasis of intracellular ATP level by catalyzing the reversible phosphotransfer between ATP and phosphocreatine. In humans, there are two cytosolic CK isoforms, the muscle-type (M) and the…
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Mi Hee Kwack, Dae-Lyong Ha, Weon Ju Lee · 2022 · International Journal of Immunopathology and Pharmacology
Objectives Particulate matter (PM) is an air pollutant that can damage human skin; antioxidants have shown some efficacy in alleviating PM-induced skin inflammation. We investigated the antioxidant effects of punicalagin,…
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Harold Pollack · 2015 · Journal of Health Politics, Policy and Law
Abstract Medicare for All, ideally implemented, could offer powerful advantages over our current health care financial system. Unfortunately, the political obstacles to such a system are formidable and are likely to remain so for decades.…
View details →Negative / Null Result Report
P. FitzPatrick, K. Antczak, F. Lynch et al. · 2023 · Irish Journal of Psychological Medicine
Abstract Objectives: The COVID pandemic has been associated with poorer mental health in youth. This study aimed to evaluate any change in General Practitioner (GP) referral pattern to Child and Adolescent Mental Health (CAMH) services…
View details →Negative / Null Result Report
Eric C. Sun, Franklin Dexter, Alex Macario et al. · 2015 · Anesthesiology
AbstractAbstract In a review of payments from private insurers for five commonly billed anesthesia codes in 229 counties in the United States from 2002 through 2010, payments to anesthesiologists in more concentrated markets were not…
View details →Negative / Null Result Report
Rebecca Schennach, Hans‐Jürgen Möller, Michael Obermeier et al. · 2015 · International Journal of Methods in Psychiatric Research
Abstract Significant changes of schizophrenia patients during inpatient treatment were evalutaed and compared to established outcome criteria. The concept of reliable and clinically significant change methods was applied to three hundred…
View details →Negative / Null Result Report
Susan C. Connors, Shemiah Nyaude, Amelia Challender et al. · 2017 · Academic Medicine
Problem In medical education, evaluating outcomes from programs intended to transform attitudes or influence career trajectories using conventional methods of monitoring is often difficult. To address this problem, the authors adapted the…
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