e-ISSN: Pending

Browse the failure-mode index

21,247 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result Report

Thalassemia and assisted reproduction: non-transfusion-dependent thalassemia shows no significant effect on live birth rates after embryo transfer

Li Fan, Liuyan Wei, Ni Tang et al. · 2025 · Frontiers in Cell and Developmental Biology

Background Thalassemia is a hereditary blood disorder that can impact fertility due to various factors such as iron overload and endocrine disruption. While the effects of iron overload on fertility outcomes in transfusion-dependent…

View details →
Negative / Null Result Report

Short message service cancellation intervention to reduce integrated sexual health and HIV ‘did not attend’ appointment rates

Andrew Tomkins, Sam Naylor, Emile Morgan · 2018 · International Journal of STD & AIDS

Did not attend (DNA) appointments create a significant impact upon resource and finance efficiency in the NHS. Despite introduction of short-message service (SMS) reminders to our patients, DNA rates remained persistently high. An option…

View details →
Negative / Null Result Report

Host Bloodmeal Source Has No Significant Effect on the Fecundity and Subsequent Larval Development Traits of the Progeny in Culicoides furens Poey (Diptera: Ceratopogonidae)

Dinesh Erram, Theodore Vincent Black, Nathan Burkett-Cadena · 2021 · Journal of Medical Entomology

Abstract Culicoides Latreille species (Diptera: Ceratopogonidae) are insects of significant medical and veterinary importance worldwide because their bites can cause major annoyance, allergic reactions, and/or pathogen transmission to…

View details →
Negative / Null Result Report

Implementation of significant mental health service change: perceptions and concerns of a mental health workforce in the context of transformation

Margaret Glogowska, Melissa Stepney, Stephen Rocks et al. · 2022 · Journal of Health Organization and Management

Purpose As part of an evaluation of the nationally mandated Child and Adolescent Mental Health Services (CAMHS) “transformation” in one foundation NHS trust, the authors explored the experiences of mental health staff involved in the…

View details →
Negative / Null Result Report

Virtual Reality-Assisted, Single-Session Exposure for Public Speaking Anxiety: Improved Self-Reports and Heart Rate but No Significant Change in Heart Rate Variability

Tonia-Flery Artemi, Thekla Konstantinou, Stephany Naziri et al. · 2025 · Virtual Worlds

Introduction: This study examines the combined use of objective physiological measures (heart rate [HR], heart rate variability [HRV]) and subjective self-reports to gain a comprehensive understanding of anxiety reduction…

View details →
Negative / Null Result Report

How Statistically Significant is the DMCA Coefficient?

Everaldo Freitas Guedes · 2021 · Fluctuation and Noise Letters

In this paper, we proposed a statistical test for the Detrending Moving-Average Cross-Correlation Coefficient ([Formula: see text]). With this methodology, it is possible to evaluate the statistical significance of [Formula: see text] for…

View details →
Negative / Null Result Report

Do ETFs outperform CEFs in fixed income investing?

C. Edward Chang, Thomas M. Krueger, H. Doug Witte · 2015 · American Journal of Business

Purpose – For a number of reasons ranging from their more recent introduction to their perceived lesser excitement relative to stock-based peers, there have been few studies of fixed income (mainly bond) exchange-traded funds (ETFs). The…

View details →
Negative / Null Result Report

Deriving significant factors for managing change in UN

James Wan, Raafat Saade, Ling Wang · 2019 · Journal of Organizational Change Management

Purpose A consequence of the UN general assembly resolution calling for increased efficiency and better utilization of resources in all its agencies, is a mandate for change. As a response to this resolution, the purpose of this paper is…

View details →
Negative / Null Result Report

Nocturnal Emissions: A Failure to Replicate

Keith F. Widaman, Jonathan L. Helm · 2012 · The American Journal of Psychology

Abstract A time series of nocturnal emissions was presented in The American Journal of Psychology in 1904. The anonymous author of this remarkable article provided the time series to support his contention that his nocturnal emissions…

View details →
Negative / Null Result Report

Preoperative walking intervention did not appear to improve patient-reported postoperative recovery in older adults with frailty traits: Randomized trial

Hammad Sadiq, Sanjeev Rampam, Jay Patel et al. · 2022 · Medicine

Objectives: To assess the impact of a preoperative walking intervention on improving postoperative recovery in at-risk frail older adult patients. Study Type: Unblinded, randomized controlled trial which assigned patients to intervention…

View details →
Failed Experiment Report

Anterior Open‐Wedge Osteotomy to Correct Sagittal and Coronal Malalignment in a Case of Failed High Tibial Osteotomy and Failed Posterior Cruciate Ligament Reconstruction

K. Raghuveer Reddy, N. Somasekhara Reddy, N. Prakash · 2024 · Arthroscopy Techniques

Abstract Anterior open‐wedge high tibial osteotomy of the proximal tibia is a reliable surgical procedure to treat genu recurvatum secondary to decreased posterior tibial slope. It is also useful in cases of posterior cruciate ligament…

View details →
Negative / Null Result Report

Where Did the Y Chromosome in the Spiny Rat Go, and How Did It Get There?

Miki Okuno, Kentaro Matsuoka, Yuta Mochimaru et al. · 2025 · Molecular Biology and Evolution

Abstract The XX/XY sex chromosome system is highly conserved across mammals, with rare exceptions where males lack a Y chromosome. Among these is the genus Tokudaia, a group of spiny rats comprising three species with unique sex chromosome…

View details →
Negative / Null Result Report

The Identification of Significant Single Nucleotide Polymorphisms for Shoot Sulfur Accumulation and Sulfur Concentration Using a Genome-Wide Association Analysis in Wild Soybean Seedlings

Hui Wang, Yu’e Zhang, Yudan Chen et al. · 2024 · Agronomy

To understand the genetic basis of soybean sulfur utilization, a genome-wide association study (GWAS) and transcriptome analysis were used to discover new sulfur utilization genes in 121 wild soybeans. The shoot sulfur accumulation (SA)…

View details →
Negative / Null Result Report

Fellow Efficiency During Anterior Cruciate Ligament Reconstruction Improves Over Time, Yet Is Less Than Experienced Physician Assistant But With No Significant Difference in Patient‐Reported Outcomes

Sean M. Hazzard, Donna M. Scarborough, Eric M. Berkson et al. · 2022 · Arthroscopy, Sports Medicine, and Rehabilitation

Purpose To evaluate the intraoperative efficiency and patient outcomes of anterior cruciate ligament reconstruction (ACLR) assisted by a sports medicine fellow over the course of the academic year compared with an experienced physician…

View details →