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Browse the failure-mode index

21,691 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result Report

Significant association of urinary alpha‐1‐microglobulin compared to urinary neutrophil gelatinase‐associated lipocalin with renal insufficiency in patients with type 2 diabetes

Guangming Chen, Xiaoyun Shan, Huabin Wang · 2021 · Nephrology

Abstract Aim Various studies have reported that urinary neutrophil gelatinase‐associated lipocalin (NGAL), an indicator of tubular damage, may be an effective biomarker of renal impairment in patients with diabetes. This study aimed to…

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Negative / Null Result Report

Strategy war games: how business can outperform the competition

Jason West, Maiko Chu, Lincoln Crooks et al. · 2018 · Journal of Business Strategy

Purpose Business wargames represent an alternative approach to challenge organisations to uncover internal capabilities through competitive actions designed to counteract external threats and address strategic mismatches. Internal…

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Negative / Null Result Report

The Acoustic Emission Method Implementation Proposition to Confirm the Presence and Assessment of Reinforcement Quality and Strength of Fiber–Cement Composites

Anna Adamczak-Bugno, Aleksandra Krampikowska · 2020 · Materials

This article proposes to use the acoustic emission (AE) method to evaluate the degree of change in the mechanical parameters of fiber–cement boards. The research was undertaken after a literature review, due to the lack of a methodology…

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Negative / Null Result Report

A Refined Model of Stress–Diathesis Relationships in Mothers With Significant Depressive Symptom Severity

Yui Matsuda, Todd A. Schwartz, YunKyung Chang et al. · 2019 · Journal of the American Psychiatric Nurses Association

BACKGROUND: Mothers’ depressive symptoms affect their children’s growth as well as physical and mental well-being. Moreover, mothers of young children with developmental delay or disability (DD) tend to have higher depressive symptoms.…

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Negative / Null Result Report

“What Did She Say? What Did She Say?” the Impact of Interpretation on Recruiting and Interviewing European Migrant Women in the United Kingdom

Mona Almalik, Alice Kiger, Janet Tucker · 2010 · International Journal of Qualitative Methods

Although a few researchers mention that involving interpreters can have an impact on the research process and research findings, little is published regarding methods of assessing the interpretation work's quality and impact. The impact of…

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Negative / Null Result Report

Where Do Women With Urinary Incontinence Find Information About Absorbent Products and How Useful Do They Find It?

Nicholas Smith, Kathleen F. Hunter, Saima Rajabali et al. · 2019 · Journal of Wound, Ostomy & Continence Nursing

PURPOSE: This study aimed to determine from what sources women with urinary and dual urinary and fecal incontinence sought and received information about incontinence and absorbent products. We also evaluated source utility. DESIGN:…

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Negative / Null Result ReportOpen accessMedicine

A Significant Effect of Pemafibrate on Hepatic Steatosis and Fibrosis Indexes in Patients With Hypertriglyceridemia

Hisayuki Katsuyama, Hidekatsu Yanai, Hiroki Adachi et al. · 2023 · Gastroenterology Research

Background: We previously reported that the selective peroxisome proliferator-activated receptor alpha modulator, pemafibrate, significantly reduced serum levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT) and…

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Negative / Null Result Report

Retrospective chart review: seasonal variation in incidence of bolus impaction is maintained and statistically significant in subgroups with atopy and eosinophilic esophagitis

Mattias Ekre, Jakob Tytor, Mogens Bove et al. · 2020 · Diseases of the Esophagus

Summary Eosinophilic esophagitis (EoE) is a chronic inflammatory condition with eosinophilic infiltration of the esophageal mucosa. The most prominent symptom is dysphagia, which may result in esophageal bolus impaction in need of surgical…

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Negative / Null Result ReportOpen accessEngineering

Statistical Analysis of Machinery Variance by Python

Joao Gabriel Ostrowski, József Menyhárt · 2020 · Acta Polytechnica Hungarica

Based particularly on data technologies, information is rapidly evolving in engineering. In mechanical engineering, maintenance is benefiting the most from data innovations, the reduction of maintenance costs, and the improvement of system…

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Negative / Null Result ReportOpen accessNeuroscience

Cognitive load, fatigue and aversive simulator symptoms but not manipulated zeitgebers affect duration perception in virtual reality

Magdalena Sabat, Bartosz Haładus, Michał Klincewicz et al. · 2022 · Scientific Reports

The perceived duration of an interval depends on numerous aspects of the passed event both endogenous, including physiological arousal, level of wakefulness, attention, and surprise, as well as exogenous such as valence, salience, or context in the environment. There is some evidence that "time-giving" cues from the environment (zeitgebers) are coupled with time perception. The movement of the sun on the horizon was demonstrated to affect interval perception in a study conducted by Schatzschneider et al. (2016) claiming that the sun's motion is a zeitgeber that influences time perception. In t

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Negative / Null Result ReportOpen accessMedicine

Replication of SARS-CoV-2 in cell lines used in public health surveillance programmes with special emphasis on biosafety

Shailesh D. Pawar, Sadhana S. Kode, Sachin S. Keng et al. · 2022 · The Indian Journal of Medical Research

Background & objectives Polio, measles, rubella, influenza and rotavirus surveillance programmes are of great public health importance globally. Virus isolation using cell culture is an integral part of such programmes. Possibility of…

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Negative / Null Result ReportOpen accessMedicine

In vivo serotonin 1A receptor hippocampal binding potential in depression and reported childhood adversity

Elizabeth Bartlett, Ashley Yttredahl, Maura Boldrini et al. · 2023 · European Psychiatry

Abstract Background Reported childhood adversity (CA) is associated with development of depression in adulthood and predicts a more severe course of illness. Although elevated serotonin 1A receptor (5-HT 1A R) binding potential, especially…

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Negative / Null Result ReportOpen accessEnvironmental Science

Subbasin Spatial Scale Effects on Hydrological Model Prediction Uncertainty of Extreme Stream Flows in the Omo Gibe River Basin, Ethiopia

Bahru M. Gebeyehu, Asie k. Jabir, Getachew Tegegne et al. · 2023 · Remote Sensing

Quantification of hydrologic model prediction uncertainty for various flow quantiles is of great importance for water resource planning and management. Thus, this study is designed to assess the effect of subbasin spatial scale on the hydrological model prediction uncertainty for different flow quantiles. The Soil Water Assessment Tool (SWAT), a geographic information system (GIS) interfaced hydrological model, was used in this study. Here, the spatial variations within the sub-basins of the Omo Gibe River basin in Ethiopia’s Abelti, Wabi, and Gecha watersheds from 1989 to 2020 were examined.

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Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology

Transcriptome Profiling in Rat Inbred Strains and Experimental Cross Reveals Discrepant Genetic Architecture of Genome-Wide Gene Expression

Pamela J. Kaisaki, Georg Otto, Karène Argoud et al. · 2016 · G3 Genes Genomes Genetics

Abstract To test the impact of genetic heterogeneity on cis- and trans-mediated mechanisms of gene expression regulation, we profiled the transcriptome of adipose tissue in 20 inbred congenic strains derived from diabetic Goto–Kakizaki (GK) rats and Brown–Norway (BN) controls, which contain well-defined blocks (1–183 Mb) of genetic polymorphisms, and in 123 genetically heterogeneous rats of an (GK × BN)F2 offspring. Within each congenic we identified 73–1351 differentially expressed genes (DEGs), only 7.7% of which mapped within the congenic blocks, and which may be regulated in cis. The remai

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Negative / Null Result ReportNeuroscience

The burden of secrecy? No effect on hill slant estimation and beanbag throwing.

Diane Pecher, Heleen van Mierlo, Rouwen Cañal‐Bruland et al. · 2015 · Journal of Experimental Psychology General

Slepian, Masicampo, Toosi, and Ambady (2012, Experiment 1) reported that participants who recalled a big secret estimated a hill as steeper than participants who recalled a small secret. This finding was interpreted as evidence that…

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Negative / Null Result ReportBusiness, Management and Accounting

Analyzing Long-run Performance of Select Initial Public Offerings Using Monthly Returns: Evidence from India

Gautam Das, Malayendu Saha, Abhijit Kundu · 2016 · Vision The Journal of Business Perspective

The anomalies in respect to initial public offering (IPO) performance in literature have stimulated multitude of research works in explaining critical issues, such as under-pricing during short-run and underperformance phenomena in the…

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Negative / Null Result ReportBiochemistry, Genetics and Molecular Biology

Purinergic Signaling Regulates the Transforming Growth Factor-β3-Induced Chondrogenic Response of Mesenchymal Stem Cells to Hydrostatic Pressure

Andrew J. Steward, Daniel J. Kelly, Diane R. Wagner · 2016 · Tissue Engineering Part A

Although hydrostatic pressure (HP) is known to regulate chondrogenic differentiation of mesenchymal stromal/stem cells (MSCs), improved insight into the mechanotransduction of HP may form the basis for novel tissue engineering strategies.…

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Negative / Null Result ReportSocial Sciences

Can Court Diversion Improve School Attendance among Elementary Students? Evidence from Five School Districts

Won Fy Lee, Clea McNeely, Janet E. Rosenbaum et al. · 2020 · Journal of Research on Educational Effectiveness

We examined the effect on attendance of a truancy court-diversion program for elementary students. Truancy court-diversion programs represent a shift from a law-and-order approach toward a public health model to address school absenteeism.…

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Negative / Null Result ReportOpen accessPsychology

Detecting the contagion effect in mass killings; a constructive example of the statistical advantages of unbinned likelihood methods

Sherry Towers, Anuj Mubayi, Carlos Castillo‐Chávez · 2018 · PLoS ONE

BACKGROUND: When attempting to statistically distinguish between a null and an alternative hypothesis, many researchers in the life and social sciences turn to binned statistical analysis methods, or methods that are simply based on the moments of a distribution (such as the mean, and variance). These methods have the advantage of simplicity of implementation, and simplicity of explanation. However, when null and alternative hypotheses manifest themselves in subtle differences in patterns in the data, binned analysis methods may be insensitive to these differences, and researchers may erroneou

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Negative / Null Result ReportOpen accessMedicine

Does gender have a significant effect on normal nerve conduction studies values?

Kawthar Al-Salmi, Farook S Wali, Ahmed Sameer Nadeem et al. · 2019 · Journal of Neurology & Stroke

Background: nerve conduction study (NCS) is a neurophysiologic medical diagnostic test used commonly to evaluate the function of the peripheral nerves. It is an extension to the clinical examination and extremely useful to diagnose and…

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