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WASTE Journal

Browse the failure-mode index

21,247 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result Report

Preventative effects of antioxidants on changes in sebocytes, outer root sheath cells, and Cutibacterium acnes -pretreated mice by particulate matter: No significant difference among antioxidants

Mi Hee Kwack, Dae-Lyong Ha, Weon Ju Lee · 2022 · International Journal of Immunopathology and Pharmacology

Objectives Particulate matter (PM) is an air pollutant that can damage human skin; antioxidants have shown some efficacy in alleviating PM-induced skin inflammation. We investigated the antioxidant effects of punicalagin,…

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Negative / Null Result Report

Challenging the understanding of significant improvement and outcome in schizophrenia – the concept of reliable and clinically significant change methods

Rebecca Schennach, Hans‐Jürgen Möller, Michael Obermeier et al. · 2015 · International Journal of Methods in Psychiatric Research

Abstract Significant changes of schizophrenia patients during inpatient treatment were evalutaed and compared to established outcome criteria. The concept of reliable and clinically significant change methods was applied to three hundred…

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Negative / Null Result Report

Evaluating the Impact of the Medical Education Partnership Initiative at the University of Zimbabwe College of Health Sciences Using the Most Significant Change Technique

Susan C. Connors, Shemiah Nyaude, Amelia Challender et al. · 2017 · Academic Medicine

Problem In medical education, evaluating outcomes from programs intended to transform attitudes or influence career trajectories using conventional methods of monitoring is often difficult. To address this problem, the authors adapted the…

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Negative / Null Result Report

Evaluating individual‐ and sample‐level response to treatment for inpatients with eating disorders: Is change clinically significant?

Colleen C. Schreyer, Allisyn Pletch, Irina A. Vanzhula et al. · 2022 · International Journal of Eating Disorders

Abstract Objective Evaluating treatment efficacy solely on whether sample‐level change is statistically significant does not indicate whether clinically significant change (CSC) has occurred at the individual‐level. We assessed whether…

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Negative / Null Result Report

Insights into protection against Mycobacterium tuberculosis infection: time to officially confirm another phenotype?

Todia P. Setiabudiawan, Philip C. Hill, Andrew R. DiNardo et al. · 2025 · Journal of Clinical Investigation

Immune correlates of protection against infection with Mycobacterium tuberculosis (Mtb) remain elusive. In this issue of the JCI , Dallmann-Sauer and authors demonstrate that lack of tuberculin skin test (TST) and interferon γ release…

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Negative / Null Result Report

Enhanced Depth Imaging Optical Coherence Tomography Technology Reveals a Significant Association Between Optic Nerve Drusen Anterior Displacement and Retinal Nerve Fiber Layer Thinning Over Time

Sara Ortiz-Toquero, Francisco J. Muñoz-Negrete, Gema Rebolleda · 2020 · Journal of Neuro-Ophthalmology

Background: Optic disc drusen (ODD) are a dynamic phenomenon, and their appearance, size, and relative location may change. The purpose of this study is to evaluate and quantify the longitudinal changes of buried ODD with enhanced depth…

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Negative / Null Result Report

Supplementation of graded levels of rumen-protected choline to a pelleted total mixed ration did not improve the growth and slaughter performance of fattening lambs

Qin Huo, Xuezhao Sun, Tingting Wu et al. · 2022 · Frontiers in Veterinary Science

Choline is an essential nutrient in ruminant diets, which contributes to the fundamental biological functions of the animal. However, choline is easily degraded in the rumen before it can be absorbed. Rumen-protected choline (RPC)…

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Negative / Null Result Report

When and how do innovation ecosystems outperform integrated organizations? On technological interdependencies and ecosystem performance

Huanren Zhang, Yimei Hu, Xianwei Shi et al. · 2022 · Industrial Management & Data Systems

Purpose Studies have documented the distinctive advantage of innovation ecosystems in integrating and recombining heterogeneous knowledge resources across firms' boundaries. However, hierarchical governance in the form of vertical…

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Negative / Null Result Report

“I had to change my attitude”: narratives of most significant change explore the experience of universal home visits to pregnant women and their spouses in Bauchi State, Nigeria

Loubna Belaid, Umaira Ansari, Khalid Omer et al. · 2021 · Archives of Public Health

Abstract Background Universal home visits to pregnant women and their spouses in Bauchi State, northern Nigeria, discussed local evidence about maternal and child health risks actionable by households. The expected results chain for…

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Negative / Null Result Report

Plyometrics Did Not Improve Jump-Landing Biomechanics in Individuals With a History of Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial

Hyunjae Jeon, Sean Krysak, Steven J. Pfeiffer et al. · 2022 · International Journal of Athletic Therapy and Training

Second anterior cruciate ligament (ACL) injury has similar biomechanical risk factors as primary injury. Standard of care rehabilitation does not adequately mitigate these biomechanical risks. This study examined the effectiveness of a…

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Negative / Null Result Report

Patient-defined outcomes for pain, fatigue, emotional distress, and interference with activities did not differ by age for individuals with musculoskeletal pain

Abigail T. Wilson, Steven Z. George, Joel E. Bialosky · 2019 · PAIN Reports

Abstract Introduction: Age impacts the prevalence and experience of musculoskeletal pain; however, it is unknown whether this factor impacts patient's anticipated outcomes after treatment. Objective: Using the Patient-Centered Outcomes…

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Negative / Null Result Report

Partial replacement of soybean meal with full-fat black soldier fly larvae meal in plant-based nursery diets did not influence fecal Escherichia coli colony forming units or improve fecal consistency when pigs were weaned into non-disinfected pens

B Christensen, C Zhu, M Niazy et al. · 2023 · Translational Animal Science

Abstract At weaning, one hundred pigs (21 d of age; 6.96 ± 0.23 kg BW) were used to determine the effect of partially replacing soybean meal (SBM) in corn- and SBM-based nursery diets on growth performance, fecal scores, Escherichia coli…

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