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Browse the failure-mode index

21,239 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Machine learning prediction model of acute kidney injury after percutaneous coronary intervention

Toshiki Kuno, Takahisa Mikami, Yuki Sahashi et al. · 2022 · Scientific Reports

Acute kidney injury (AKI) after percutaneous coronary intervention (PCI) is associated with a significant risk of morbidity and mortality. The traditional risk model provided by the National Cardiovascular Data Registry (NCDR) is useful for predicting the preprocedural risk of AKI, although the scoring system requires a number of clinical contents. We sought to examine whether machine learning (ML) techniques could predict AKI with fewer NCDR-AKI risk model variables within a comparable PCI database in Japan. We evaluated 19,222 consecutive patients undergoing PCI between 2008 and 2019 in a Ja

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Negative / Null Result Report

Effect of significant data loss on identifying electric signals that precede rupture estimated by detrended fluctuation analysis in natural time

E. S. Skordas, N. V. Sarlis, P. A. Varotsos · 2010 · Chaos: An Interdisciplinary Journal of Nonlinear Science

Electric field variations that appear before rupture have been recently studied by employing the detrended fluctuation analysis (DFA) to quantify their long-range temporal correlations. These studies revealed that seismic electric signal…

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Negative / Null Result ReportOpen accessMedicine

Significant Association of Serum Adiponectin and Creatine Kinase-MB Levels in ST-Segment Elevation Myocardial Infarction

Tomoaki Natsukawa, Norikazu Maeda, Shiro Fukuda et al. · 2017 · Journal of Atherosclerosis and Thrombosis

AIMS: Adiponectin, an adipocyte-specific secretory protein, abundantly exists in the blood stream while its concentration paradoxically decreases in obesity. Hypoadiponectinemia is one of risks of cardiovascular diseases. However, impact…

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Negative / Null Result ReportSocial Sciences

Do minority-language and majority-language students benefit from pedagogical translanguaging in early foreign language development?

Holger Hopp, Teresa Kieseier, Jenny Jakisch et al. · 2021 · Multilingua

Abstract This paper reports findings of a project on pedagogical translanguaging (PTL) among 128 fourth-grade students learning English as a foreign language (EFL) in German primary schools. Over a period of six months, 20% of lesson time…

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Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance

Fundamental Analysis VS Technical analysis: The Comparison of Two Analysis in Malaysia Stock Market

Shaharudin Jakpar, Michael Tinggi, Akmal Hisham Tak et al. · 2018 · UNIMAS Review of Accounting and Finance

This study is conducted to analyse the credibility of the fundamental analysis and technical analysis on predicting the stock return and compare both models to determine which model is more credible to be used as a good trading strategy by…

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Negative / Null Result ReportOpen accessMedicine

Performance of arthroscopic irrigation systems assessed with automatic blood detection

Gabriëlle J. M. Tuijthof, M. M. de Vaal, I. N. Sierevelt et al. · 2011 · Knee Surgery Sports Traumatology Arthroscopy

PURPOSE: During arthroscopies, bleeding episodes occur as a result of tissue damage. Irrigation systems assist in minimizing these disturbances. The performance of three arthroscopic irrigation systems in clearing bleeding episodes was…

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Negative / Null Result ReportOpen accessNeuroscience

Propensity or diversity? Investigating how mind wandering influences the incubation effect of creativity

Shan-Chuan Teng, Yunn-Wen Lien · 2022 · PLoS ONE

Mind wandering has been argued to be beneficial for breaking through mental impasses, which leads to better creative performance upon a second attempt (i.e., the incubation effect). However, the evidence is inconsistent. Different from the propensity for mind wandering that has been the focus of past studies, in this study we further examined the role of diversity (i.e., non-repetitiveness of mind wandering respective to its content) and types of mind wandering along the dimensions of intentionality and awareness during incubation when engaging in a 0-back task (a mind wandering-prone conditio

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Negative / Null Result ReportPsychology

Structured assessment of suicide risk in a psychiatric emergency service: Psychometric evaluation of the Nurses’ Global Assessment of Suicide Risk scale (NGASR)

Mark van Veen, Inge van Weeghel, Bauke Koekkoek et al. · 2014 · International Journal of Social Psychiatry

BACKGROUND: Risk of suicide is notoriously difficult to assess, and no gold standard is available, in terms of an instrument of first choice. Many different instruments are in use, among which are some that are not properly…

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Negative / Null Result ReportOpen accessMedicine

Cystatin C– and Creatinine-Based Estimates of Renal Function and Their Value for Risk Prediction in Patients with Acute Coronary Syndrome: Results from the PLATelet Inhibition and Patient Outcomes (PLATO) Study

Axel Åkerblom, Lars Wallentin, Anders Larsson et al. · 2013 · Clinical Chemistry

BACKGROUND: The estimated glomerular filtration rate (eGFR) independently predicts cardiovascular death or myocardial infarction (MI) and can be estimated by creatinine and cystatin C concentrations. We evaluated 2 different cystatin C…

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Negative / Null Result ReportOpen accessMedicine

The American Association for the Surgery of Trauma renal injury grading scale: Implications of the 2018 revisions for injury reclassification and predicting bleeding interventions

Sorena Keihani, Douglas Rogers, Bryn Putbrese et al. · 2019 · The Journal of Trauma: Injury, Infection, and Critical Care

BACKGROUND: In 2018, the American Association for the Surgery of Trauma (AAST) published revisions to the renal injury grading system to reflect the increased reliance on computed tomography scans and non-operative management of high-grade…

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Negative / Null Result ReportOpen accessMedicine

Predicting vaginal birth after previous cesarean: Using machine‐learning models and a population‐based cohort in Sweden

Charlotte Lindblad Wollmann, Kyle D. Hart, Can Liu et al. · 2020 · Acta Obstetricia Et Gynecologica Scandinavica

INTRODUCTION: Predicting a woman's probability of vaginal birth after cesarean could facilitate the antenatal decision-making process. Having a previous vaginal birth strongly predicts vaginal birth after cesarean. Delivery outcome in…

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Negative / Null Result ReportOpen accessMedicine

Estimated GFR and Mortality in Older Men: Are All eGFR Formulae Equal?

Muna Canales, Terri Blackwell, Areef Ishani et al. · 2016 · American Journal of Nephrology

<b><i>Background:</i></b> Recently, the first estimated glomerular filtration rate (eGFR) formula specifically developed for community-dwelling older adults, the Berlin Initiative Study Equation 2 (BIS2), was…

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Negative / Null Result Report

Anomalous metals: From “failed superconductor” to “failed insulator”

Xinyang Zhang, Alexander Palevski, Aharon Kapitulnik · 2022 · Proceedings of the National Academy of Sciences

Resistivity saturation is found on both superconducting and insulating sides of an “avoided” magnetic-field-tuned superconductor-to-insulator transition (H-SIT) in a two-dimensional In/InO x composite, where the anomalous metallic behavior…

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Negative / Null Result Report

Biomechanical Comparison of 3 Medial Patellofemoral Complex Reconstruction Techniques Shows Medial Overconstraint but No Significant Difference in Patella Lateralization and Contact Pressure

Falko Dahm, Hassan Syed, Sebastian Tomescu et al. · 2022 · Arthroscopy

Purpose The purpose of this study was to investigate biomechanical differences of medial patellofemoral ligament (MPFL) reconstruction, medial quadriceps tendon femoral ligament (MQTFL) reconstruction, and a combination of these techniques…

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Negative / Null Result Report

The dog that failed to bark

Tom Burns · 2010 · The Psychiatrist

Summary UK mental healh services have been distinguished by their continuity of care but recently there has been a move to separating consultant responsibility for in-patient and out-patient care. Local examples of the success of this…

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Negative / Null Result ReportOpen accessMedicine

The Error of Estimated GFR in Type 2 Diabetes Mellitus

Sergio Luis‐Lima, Tomás H. Higuera Linares, Laura Henríquez-Gómez et al. · 2019 · Journal of Clinical Medicine

Type 2 diabetes mellitus represents 30-50% of the cases of end stage renal disease worldwide. Thus, a correct evaluation of renal function in patients with diabetes is crucial to prevent or ameliorate diabetes-associated kidney disease. The reliability of formulas to estimate renal function is still unclear, in particular, those new equations based on cystatin-C or the combination of creatinine and cystatin-C. We aimed to assess the error of the available formulas to estimate glomerular filtration rate in diabetic patients. We evaluated the error of creatinine and/or cystatin-C based formulas

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Negative / Null Result ReportOpen accessMedicine

Improving PCASL at ultra‐high field using a VERSE‐guided parallel transmission strategy

Yan Tong, Peter Jezzard, Thomas W. Okell et al. · 2020 · Magnetic Resonance in Medicine

PURPOSE: To improve the labeling efficiency of pseudo-continuous arterial spin labeling (PCASL) at 7T using parallel transmission (pTx). METHODS: maps were acquired in the labeling plane for tagging pulse design. Complex weights of the labeling pulses for each of the 8 transmit channels were calculated to produce a homogenous radiofrequency (RF) -shimmed labeling across the ROIs. Variable-Rate Selective Excitation (VERSE) pulses were also implemented as a part of the labeling pulse train. Whole-brain perfusion-weighted images were acquired under conditions of RF shimming, VERSE with RF shimmin

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Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology

Significant association between renal function and amyloid-positive area in renal biopsy specimens in AL amyloidosis

Takeshi Kuroda, Naohito Tanabe, Daisuke Kobayashi et al. · 2012 · BMC Nephrology

BACKGROUND: The kidney is a major target organ for systemic amyloidosis that often affects the kidney including proteinura, and elevated serum creatinine (Cr). The correlation between amount of amyloid deposits and clinical parameters is not known. The aim of this study was to clarify correlation the amyloid area in all renal biopsy specimen and clinical parameters. METHODS: Fifty-eight patients with an established diagnosis of AL amyloidosis participated in the study. All patients showed amyloid deposits in renal biopsies. We retrospectively investigated the correlation between clinical data

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Negative / Null Result ReportOpen accessDentistry

Antiseptics and microcosm biofilm formation on titanium surfaces

Georgia Verardi, Maximiliano Sérgio Cenci, Tamires Timm Maske et al. · 2016 · Brazilian Oral Research

Oral rehabilitation with osseointegrated implants is a way to restore esthetics and masticatory function in edentulous patients, but bacterial colonization around the implants may lead to mucositis or peri-implantitis and consequent implant loss. Peri-implantitis is the main complication of oral rehabilitation with dental implants and, therefore, it is necessary to take into account the potential effects of antiseptics such as chlorhexidine (CHX), chloramine T (CHT), triclosan (TRI), and essential oils (EO) on bacterial adhesion and on biofilm formation. To assess the action of these substance

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Negative / Null Result ReportDentistry

Toothpastes containing abrasive and chemical whitening agents: efficacy in reducing extrinsic dental staining.

Cristina Neves Girao Salgado Soares, Flávia Lucisano Botelho do Amaral, Marcelo Ferraz Mesquita et al. · 2017 · PubMed

This in vitro study evaluated the efficacy of toothpastes containing abrasive and chemical whitening agents in reducing the extrinsic discoloration of dental enamel. Sixty slabs of dentin from human teeth were sealed so that only the…

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Negative / Null Result Report

Climate change and pro-environmental behaviours: the significant environmental challenges of livelihoods

Nadia A. Abdelmegeed Abdelwahed, Bahadur Ali Soomro, Naimatullah Shah · 2022 · Management of Environmental Quality: An International Journal

Purpose The study investigates the intention to adopt climate change and the pro-environmental behaviours among the residents of a developing country (Pakistan) through the theory of planned behaviour (TPB). Design/methodology/approach…

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Negative / Null Result Report

Exercise Strain Echocardiography in Patients With a Hemodynamically Significant Myocardial Bridge Assessed by Physiological Study

Yukari Kobayashi, Jennifer A. Tremmel, Yuhei Kobayashi et al. · 2015 · Journal of the American Heart Association

Background Although a myocardial bridge ( MB ) is often regarded as a benign coronary variant, recent studies have associated MB with focal myocardial ischemia. The physiological consequences of MB on ventricular function during stress…

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