Modulation of Remote Ischemic Preconditioning by Proinflammatory Cytokines in Renal Transplant Recipients
Homero Zapata-Chavira; Marco Hernández-Guedea; Julio César Jiménez-Pérez; Edelmiro Pérez-Rodríguez; Linda Muñoz-Espinosa; Gerardo Muñoz-Maldonado; Paula Cordero-Pérez · 2019 · Journal of Investigative Surgery
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Aim: Remote ischemic preconditioning (RIPC) has been used as a strategy to reduce acute renal injury and ischemia-reperfusion injury (IRI) in renal transplantation (RT) with controversial results. Objective: To determine if RIPC modifies IRI in cadaveric RT recipients through inflammatory mediators and graft function. Methods: Twenty-nine RT recipients were studied, 12 in the control group (CG) and 17 in the RIPC group. RIPC which was performed on donors using a pneumatic tourniquet placed on both thighs for 10 min followed by the determination of IL-1, IL-6, TNF-α, VEGF, and ICAM-1, and hemat
Abstract by Homero Zapata-Chavira; Marco Hernández-Guedea; Julio César Jiménez-Pérez; Edelmiro Pérez-Rodríguez; Linda Muñoz-Espinosa; Gerardo Muñoz-Maldonado; Paula Cordero-Pérez, Journal of Investigative Surgery (2019) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1080/08941939.2017.1375052