Evaluating Artificial Intelligence’s Role in Developing Research Questions in Head and Neck Reconstruction
Sebastian Holm, MD; Mario Zambrana, MD; Juan E. Berner, MD, PhD; Reza Tabrisi, MD; Fredrik Landström, MD, PhD; Dhafir Hanoon, MD; Johann Zdolsek, MD, PhD · 2025 · Plastic and Reconstructive Surgery, Global Open
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Summary:. Generative artificial intelligence (AI) large language models are an emerging technology, with ChatGPT and Gemini being 2 well-known examples. The current literature discusses clinical applications and limitations of AI, but its role in research has not yet been extensively evaluated. This study aimed to assess the role of ChatGPT and Gemini in developing novel and clinically relevant research ideas (RIs) for systematic reviews (SRs) in head and neck reconstruction. ChatGPT and Gemini were prompted to provide 10 novel and clinically relevant RIs for SRs in the following domains: head
Abstract by Sebastian Holm, MD; Mario Zambrana, MD; Juan E. Berner, MD, PhD; Reza Tabrisi, MD; Fredrik Landström, MD, PhD; Dhafir Hanoon, MD; Johann Zdolsek, MD, PhD, Plastic and Reconstructive Surgery, Global Open (2025) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1097/gox.0000000000007057