e-ISSN: Pending

Browse the failure-mode index

21,778 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Replication FailureMedicine

Facial shape and self-perceived personality traits in young adults.

Gkantidis N, Tsikouriadou E, Halazonetis D et al. · 2026 · Scientific reports

The present study investigated the association between facial shape and self-perceived personality and psychosocial traits. The study population consisted of 613 young adults (399 females and 214 males) aged 21-35 years, with similar…

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Negative / Null Result ReportMedicine

Distinct Pause Patterns in Autism: Effects of Sex and Conversational Context in French-Speaking (Pre)adolescents.

Belenger M, Dumont C, Geelhand P et al. · 2026 · Journal of speech, language, and hearing research : JSLHR

Purpose We investigated sex differences in the production of pauses in autistic (pre-)adolescents in two conversational contexts: a monologue and an interactive discussion. Method This study included 107 French-speaking participants ( M…

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Negative / Null Result ReportMedicine

Efficacy analysis of CAR-T cells against CD123-positive malignant tumors and exploration of the feasibility of combination therapy with venetoclax.

Zhang M, Chai X, Zhang X et al. · 2026 · Annals of hematology

Chimeric antigen receptor T cells (CAR-T cells) have been widely applied in hematologic malignancies. It has shown limited efficacy in the treatment of myeloid neoplasms. We retrospectively analyzed the safety and efficacy of CD123 CAR-T…

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Negative / Null Result ReportMedicine

Impact of an Individualized Dietary Intervention on Body Composition and Clinical Outcomes in Patients with Neovascular Age-Related Macular Degeneration: A Pilot Study.

Szulim D, Kucharska E, Machalińska A et al. · 2026 · Nutrients

Background/Objectives : Age-related macular degeneration (AMD) is a leading cause of permanent deterioration of central vision in elderly people. While anti-VEGF therapy remains the standard of care for neovascular AMD, disease progression…

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Negative / Null Result ReportMedicine

The Impact of a Unique Military Treatment Facility-Based Sports Medicine Model on Readiness in the Army: A Prospective Longitudinal Analysis Comparing 2 Military Health System Entry Portal Pathways on the Duration of Healthcare Management and the Incidence of Recurrence Within 24 Months.

Suttles S, Boeth RR, Frazier M et al. · 2026 · Military medicine

Objective Describe an innovative Sports Medicine clinic design implemented in an outpatient Physical Therapy (PT) clinic within a Military Treatment Facility (MTF) for both referral and direct access (DA) entry portal pathways, and to…

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Negative / Null Result ReportMedicine

Effect of hydrogen peroxide disinfectant on the flexural strength of different custom impression tray materials fabricated using conventional and digital methods.

Lengerli Efe A, Özen Sütüven E, Uçar Y et al. · 2026 · International journal of computerized dentistry

Aim The aim was to evaluate the effect of hydrogen peroxide disinfectant exposure for 60 minutes -representing the longest exposure time recommended for achieving the widest antimicrobial spectrum- on the flexural strength (FS) of…

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Negative / Null Result ReportOpen accessMedicine

Haptic perception of 2.5D surface feature height.

Hwang I, Yun S, Park J · 2026 · Scientific reports

The present study investigates the human haptic perception of 2.5D dome-shaped surface features in terms of difference and absolute thresholds. We conducted two experiments to measure the thresholds, analyzing the effect of sample base…

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Negative / Null Result ReportOpen accessMedicine

ANO1 (TMEM16A) Genetic Variants, Promoter Methylation, and Chloride Dysregulation in Pulmonary Hypertension.

Yaman İ, Korkmaz H, Akağaç AE et al. · 2026 · Journal of cardiovascular development and disease

Background Pulmonary arterial hypertension (PAH) is a rare and progressive disorder characterized by increased pulmonary vascular resistance and vascular remodeling. Genetic polymorphisms, epigenetic modifications, and ion channel…

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Negative / Null Result ReportOpen accessMedicine

Association between Helicobacter pylori infection and thyroid dysfunction in adults visiting a tertiary care hospital in Karachi, Pakistan: a cross-sectional study.

Jahangeer A, Jabeen R, Fatima S et al. · 2026 · BMC endocrine disorders

Background Thyroid dysfunction and Helicobacter pylori (H. pylori) infection are both highly prevalent in Pakistan. Several studies have proposed a potential immunological link between H. pylori infection and autoimmune thyroid disease,…

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Negative / Null Result ReportOpen accessMedicine

Immunohistochemical expression of Stomatin-Like protein 2 and trophoblast cell surface antigen 2 in papillary thyroid carcinoma in comparison to other thyroid lesions.

Elmetwally AA, Khashaba MH, Wagih HM et al. · 2026 · Diagnostic pathology

BACKGROUND: Thyroid carcinoma is a common tumor affecting the Egyptian population accounting for 2% of newly diagnosed cases of cancer in Egypt yearly and constituting 7.73% of 5 year prevalence in Egypt. Stomatin-Like Protein 2 (SLP-2)…

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Negative / Null Result ReportMedicine

The Association Between the STOP-Bang Score and the Integrated Pulmonary Index in Patients Undergoing Endobronchial Ultrasound with Sedation: The STOP OSA-IPI Cohort Study.

Ozden Sertcelik U, Turker M, Sertcelik A et al. · 2026 · Medicina (Kaunas, Lithuania)

Background and Perspectives : Obstructive sleep apnea (OSA) is a prevalent condition associated with increased perioperative risks. Endobronchial ultrasound (EBUS), a diagnostic and staging procedure requiring deep sedation, may pose…

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Negative / Null Result ReportMedicine

Study of phosphorylated ribosomal protein S6 (pS6) in the clinical outcomes of patients undergoing hepatectomy for metastatic colorectal cancer.

Henriques Cavalcanti Torres de Melo R, de Barros Silva PG, Neto HFEC et al. · 2026 · World journal of surgical oncology

Introduction Colorectal cancer (CRC) is one of the most prevalent malignancies worldwide, with up to 50% of patients developing metastatic disease, predominantly involving the liver. Hepatectomy remains the gold standard for resectable…

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