21,770 real negative results, null findings, and replication failures. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Wendler M, Leister D, Kleine T · 2026 · The New phytologist
Plastid-to-nucleus retrograde signaling coordinates nuclear gene expression with the developmental and physiological state of plastids. GENOMES UNCOUPLED 1 (GUN1), a chloroplast-localized PPR-SMR protein, remains a central yet poorly…
View details →Mallus F, Yang Y, Kia SM et al. · 2026 · Preprint
Abstract Spectral features derived from electroencephalography (EEG) have long been proposed as biomarkers of brain dysfunction, yet few have gained consensus or entered clinical practice. A key obstacle is the lack of harmonized,…
View details →Gottfried JA, Shen C, Morgan D et al. · 2026 · Optics express
In a previous publication [Opt. Express21, 28182 (2013)10.1364/OE.21.028182], Daido et al . reported that solid samples of metallic sodium exhibited high transparency of vacuum ultraviolet light through several millimeter-thick samples.…
View details →Azaad S, Laham S, Sebanz N · 2026 · Preprint
Evidence from joint action research suggests that a suite of spontaneous cognitive and perceptual processes underpins our ability to coordinate with others. We tested whether people spontaneously perceive affordances (or action…
View details →Weber S, Kemp SA, Hinder MR · 2026 · Cognitive, affective & behavioral neuroscience
Action cancellation represents a fundamental aspect of human motor control. Nonetheless, the behavioural paradigms used to study it are methodologically diverse and capture an incompletely understood combination of processes. Advancing…
View details →Macaulay C, Scheepers C · 2025 · Preprint
A Theory of Magnitude (AToM) (Walsh, 2003; Walsh, 2014) attempts to explain avisuo-spatial bias observed across magnitude processing domains (e.g., numerical, temporal).It proposes a generalised processing system which maps mental…
View details →Wladis EJ, Aakalu VK, Dagi Glass LR et al. · 2026 · Ophthalmology
Objective To review the literature on the benefits and risks of systemic corticosteroids in the setting of orbital cellulitis. Methods A literature search was last performed in the PubMed database in August 2025. Articles were limited to…
View details →Benyoucef R, Goubet M, Barrat A et al. · 2026 · European radiology
Objectives External validation of six radiomic models published in three studies: two distinguishing benign from malignant lesions (study 1) and four distinguishing pleomorphic adenomas from Warthin's tumors (studies 2 and 3). Materials…
View details →Tenney ER, Rochford K, Stillwell A et al. · 2026 · Psychological science
This is a registered report to directly replicate the primary finding in Hecht and Proffitt (1995). Hecht and Proffitt found that those with occupational experience handling liquid in containers performed worse at solving a water-level…
View details →Jajcay N, Tomeček D, Fajnerová I et al. · 2026 · Preprint
An increasing number of studies are currently focusing on ‘personality neuroscience’, a term denoting the research aimed at neuroimaging correlates of inter-individual temperament and character variability. Among other methods, a graph…
View details →Chandran S, Vinjé J, Huynh K et al. · 2026 · Preprint
Human intestinal enteroids (HIE) and zebrafish larvae (ZF) models support the replication of certain strains of human norovirus (HuNoV), the leading cause of viral gastroenteritis worldwide. The replication of 17 HuNoV (9 genotypes)…
View details →Dhanda N, Ziano I, Ching KH et al. · 2025 · Personality & social psychology bulletin
This article presents preregistered replications of three influential studies in the field of escalation of commitment and regret aversion. In Study 1, we found partial support for Staw's (1976) article on the effects of personal…
View details →Pachunka A, Jeffries JB, Karr L et al. · 2025 · Preprint
Interacting with animals can improve health and well-being across the lifespan. Some programs such as 4-H and FFA center around youth interacting with animals, potentially enhancing youth development. Mueller (2014) investigated whether…
View details →Adinugroho I, Bentall R, Stafford T · 2025 · Preprint
This is the second study to attempt replication of Banas et al (2023) on inoculation messages. The original experiment demonstrated that inoculation messages could foster resistance to anti-vaccine conspiracy theories without significantly…
View details →Adinugroho I, Bentall R, Stafford T · 2025 · Preprint
This is the first study to attempt replication of Banas et al (2023) on inoculation messages. The original experiment demonstrated that inoculation messages could stimulate resistance to anti-vaccine conspiracy theories. However, a gap was…
View details →Adinugroho I, Bentall R, Stafford T · 2025 · Preprint
This is the first study to attempt replication of Banas et al (2023) on inoculation messages. The original experiment demonstrated that inoculation messages could stimulate resistance to anti-vaccine conspiracy theories. However, a gap was…
View details →Nguyen A, Scheltienne M, Thiam S et al. · 2025 · Preprint
Flow is a state where individuals are fully focused on a task, know what to do and perform at full capacity. Despite this intense engagement, flow is not experienced as tiring; instead, it is intrinsically rewarding and promotes…
View details →Remouchamps R, Majerus S, Kowialiewski B · 2025 · Preprint
In verbal working memory (WM), the second occurrence of an item in a memory list generally leads to impaired recall performance, a phenomenon called the “Ranschburg effect”. One explanation for this effect is response suppression, by which…
View details →Slis A, Parrell B · 2025 · Preprint
Sensory errors, mismatches between predicted sensory outcomes of movement and reafferent sensory feedback, drive changes in the feedforward control of future motor behavior that correct for those errors. Across a wide variety of motor…
View details →Maylott SE, Zeng G, Leung TS et al. · 2025 · Journal of neuroscience research
Sudden infant death syndrome (SIDS)-the sudden and unexplained death of a seemingly healthy infant, < 1 year old-may be associated with abnormalities in the brain regions that underlie breathing and arousal during sleep. While post-mortem…
View details →Petersen Dias A, Orsel K, Gammariello CS et al. · 2025 · Research in Veterinary Science
Digital dermatitis (DD) is a polymicrobial, multifactorial hoof disorder with an undefined etiology, and existing animal models fail to induce a fast, standardized infection in bovine skin. This study explored bacterial inoculation methods…
View details →Evans ND, Fetterman AK · 2026 · Public understanding of science (Bristol, England)
Admitting that one's research findings are wrong involves admitting a potential instance of incompetence, which can keep scientists from engaging in wrongness admission. However, wrongness admission can yield favorable perceptions. In five…
View details →Meier M, Gurri L, Beck K et al. · 2025 · Preprint
Childhood maltreatment (CM) has long-lasting effects on physical and mental health with CM type specific effects being reported. Epigenetic processes, like deoxyribonucleic acid methylation (DNAm), might mediate this link, and CM types…
View details →Frizado AP, O'Reilly MA · 2025 · Physics in medicine and biology
Objective. Although less established than transcranial focused ultrasound (FUS), transvertebral FUS is being developed to treat spinal cord pathologies. Transvertebral sonication of the spinal cord for microbubble-mediated drug delivery…
View details →Appel H, Carmen-Orozco RP, Santiago CP et al. · 2025 · Preprint
The RNA-binding protein Ptbp1 has been proposed as a master regulator of neuronal fate, repressing neurogenesis through its effects on alternative splicing and miRNA maturation. While prior studies using RNA interference suggested that…
View details →Van der Snickt T, Ailliet S, Bassini S et al. · 2025 · Preprint
Enzyme-free isothermal amplification methods offer a promising alternative to enzymatic assays for nucleic acid detection, particularly in low-resource settings. The nonenzymatic isothermal strand displacement and amplification (NISDA)…
View details →Walleczek J, von Stillfried N, Schmidt S et al. · 2025 · Preprint
This metascientific project studied the replicability of Bem Experiment 1, which had claimed a precognitive effect, i.e., the ability to successfully guess the outcome of future random events (Bem. J Pers Soc Psychol. 2011;100: 407-25).…
View details →Li L, Wang Y, Du Z et al. · 2026 · Metabolism: clinical and experimental
Background and aims Targeting key enzymes in hepatic de novo lipogenesis (DNL) presents a promising strategy for treating hypercholesterolemia. However, the precise regulatory mechanisms governing hepatic DNL remain incompletely…
View details →Petersen Dias A, Orsel K, Gammariello CS et al. · 2025 · Research in veterinary science
Digital dermatitis (DD) is a polymicrobial, multifactorial hoof disorder with an undefined etiology, and existing animal models fail to induce a fast, standardized infection in bovine skin. This study explored bacterial inoculation methods…
View details →Willroth EC, Young G, Ford BQ et al. · 2025 · Psychological science
Certain emotion-regulation strategies (e.g., reappraisal) are associated with better well-being and are therefore seen as adaptive (health-promoting) strategies. However, it is unlikely that any strategy is adaptive regardless of context.…
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