21,770 real negative results, null findings, and replication failures. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Wu R, Jin H, Shen J · 2025 · Preprint
Abstract Despite known benefits in normal diet, capsaicin's effects under obesogenic conditions remain unexplored. Based on capsaicin's established metabolic benefits, we hypothesized that capsaicin supplementation would extend lifespan in…
View details →Clucas K, Saito A · 2026 · The Physician and sportsmedicine
Background Medial elbow injuries occur in approximately one-third of all young baseball players and are characterized by injuries to the bone and cartilaginous growth plates. Bone mineral mass, a representative of bone strength, may show…
View details →Adams R, Deroche MLD · 2025 · The Journal of the Acoustical Society of America
To extract a voice from a background of competing speakers, the human brain exploits voice pitch (harmonic cues) and spatial location (binaural cues) to separate speakers perceptually, and effectively attenuates the background (anything…
View details →LeBlanc MR, Zhou X, Baggett CD et al. · 2026 · Cancer medicine
Background This study aims to describe time to treatment initiation for Black and White older adults with multiple myeloma (MM), and to test the hypothesis that Black/White disparities in treatment initiation have increased over time.…
View details →Ogawa K, Shimatani K, Endo K et al. · 2026 · Public health
Objectives This study examined the association between individual housing cost burden and depressive symptoms, hypothesizing stronger associations particularly in primary breadwinner men who may bear disproportionate financial…
View details →Ruan N, Ng AJ, Christianson JP · 2025 · Preprint
ABSTRACT Competing motivational drives are integral to survival and encompass a spectrum of internal physiological needs such as hunger to external goals like social connection. Elucidating how these motivational states interact at the…
View details →Song J, Pennartz KJ, Caldwell JT et al. · 2026 · European journal of applied physiology
Purpose Near-infrared spectroscopy (NIRS) with vascular occlusion testing (VOT) is used to assess skeletal muscle tissue oxygenation (StO 2 ) responses. Differences in NIRS-VOT outcomes exist between trained and untrained groups; however,…
View details →Kemp LT, Smeets T, Jansen A et al. · 2026 · Journal of behavior therapy and experimental psychiatry
While studying appetitive and aversive conditioning is common in psychopathology research, studies that measure both types of learning simultaneously are rare. To gain insight into the role of appetitive and aversive learning in the…
View details →Del Grosso SJ, Nichols KL, Delgado JA et al. · 2025 · Nutrient cycling in agroecosystems.
Grassland soils managed with livestock grazing can act as sources and sinks for methane (CH₄) and nitrous oxide (N₂O), but, in aggregate, are typically a source of N₂O and a sink for CH₄. Previously, we observed higher N₂O losses from…
View details →Arriero-Cabañero A, Díaz-Rubio N, Talabán-Rocha C et al. · 2025 · Molecular neurobiology
Pyruvate kinases are key enzymes of glycolytic metabolism of neurons and glia. One of them, pyruvate kinase M2 (PKM2) can also act as a transcriptional regulator and in this function has been implicated in several neurodegenerative…
View details →Moreau AL, Rappaport BI, Saturday ML et al. · 2026 · Journal of psychiatric research
Intolerance of uncertainty (IU) is an individual difference dimension reflecting negative cognitive, emotional, and behavioral responses to uncertainty. IU is an important etiological and maintaining mechanism of internalizing…
View details →Elster A, Ron L · 2026 · Journal of personality
Introduction Behavior is not solely determined by individual dispositions or situational demands, but by the dynamic interplay between them. The current research investigates the contextual sensitivity of behavioral determinants by…
View details →Ye J, Hoàng DĐ, Liu X et al. · 2025 · Biochemical and Biophysical Research Communications
Schisandrin B (SchB), a natural lignan with reported organ-protective effects, was hypothesized to ameliorate severe acute pancreatitis (SAP). We investigated the effects of SchB (30 and 60 mg/kg) in a caerulein-induced mouse model of SAP…
View details →Raidl P, Vogl A, Dreisörner A et al. · 2026 · Psychophysiology
Prior evidence suggests that individuals with higher fitness exhibit attenuated endocrine and autonomic responses to acute psychological and physical stressors. However, it remains unclear whether this stress-buffering effect depends on…
View details →Varden Gjerde K, Bartz-Johannessen C, Løberg EM et al. · 2026 · Schizophrenia research
Background Schizophrenia patho-etiology may involve endothelial inflammation and blood-brain barrier (BBB) dysregulation with cellular adhesion molecules (CAMs) as important mediators. CAMs are essential for cellular integrity but can show…
View details →Chhabra BR, Madan AK, Tichansky DS · 2025 · Cureus
Introduction Relationships with industry may create a potential conflict of interest (COI). Disclosure of COI is essential for integrity of educational programming. In 2013, Center for Medicare and Medicaid Services (CMS) developed the…
View details →Lin X, Lee JB, Phua HP et al. · 2025 · Preprint
Introduction Migrants are drawn to high-income countries (HICs) for employment, often in sectors deemed difficult, risky, and low paying. However, they experience more injuries and deaths and face barriers to healthcare. The World Health…
View details →Hashimoto C, Yoshino A, Hida S et al. · 2025 · Preprint
Abstract Background With the increasing diversity of nationalities in Japan, the number of foreign patients with limited Japanese language proficiency is growing. While various multilingual support resources have been developed in recent…
View details →Spacey OG, Jones OR, Record S et al. · 2025 · Preprint
The population dynamics and life histories of macroparasites are fundamental to examine their impacts on hosts and ecosystems. Still, macroparasite population models often ignore parasite individual heterogeneity and are rarely applied to…
View details →Brink KJ, Wiles TM, Stergiou N et al. · 2025 · Human movement science
The Optimal Movement Variability Hypothesis posits that healthy movements exhibit an optimal structure of variability, characterized by fractal patterns, which confer both stability and flexibility in motor control. This optimal,…
View details →Weber RE, Schulze KM, Kenney NJ et al. · 2025 · American journal of cancer research
Breast cancer patients' maximal O 2 uptake (V̇O 2 max) values average 60-80% of age-predicted values which is often attributed to adjuvant therapy rather than risk factors, comorbidities, or the tumor and associated factors (e.g.,…
View details →Chang DS, Littlepage-Saunders M, Hochstein MJ et al. · 2023 · Preprint
Convergent lines of evidence from animal models suggest that disrupted metabotropic glutamate receptor 2 (mGlu 2 ) function promotes high levels of drug consumption for a variety of psychoactive drugs including alcohol, opioids, and…
View details →Erickson MG, Reinhardt LA, Svaren L et al. · 2024 · Journal of dairy science
Reducing dietary CP is a well-established means to improve N use efficiency. Yet, few studies have considered if transient restrictions in dietary CP could reduce the environmental footprint of late-lactation cows. We hypothesized that the…
View details →Colomer-Poveda D, Mera-González I, Marcos-Frutos D et al. · 2026 · European journal of applied physiology
PURPOSE: The aim of this triple-blind, placebo-controlled study was to determine the effects of anodal transcranial direct current stimulation (a-tDCS) applied over the primary motor cortex (M1) and the dorsolateral prefrontal cortex…
View details →Turan G, Spiertz V, Bein O et al. · 2023 · Preprint
The human brain is postulated to function as a prediction machine, constantly comparing incoming sensory input to predictions based on past experiences. When an event contradicts these predictions, it results in a prediction error (PE),…
View details →Agir M, Sahin K, Pulatkan A et al. · 2026 · JSES international
Background Rotator cuff tears are a leading cause of shoulder pain, with high rerupture rates despite advancements in surgical techniques. Tendon-to-bone healing failure is often attributed to insufficient fibrocartilage regeneration at…
View details →Meier K, van Hoeken D, Kager CCM et al. · 2025 · The International journal of eating disorders
Objective This study examined the impact of the COVID-19 pandemic on incidence rates of anorexia nervosa (AN) and bulimia nervosa (BN) in Dutch primary care by comparing pre-pandemic (2015-2019) and in-pandemic (2020-2022) periods. We…
View details →Haucke M, Heinz A, Heinzel S et al. · 2025 · European archives of psychiatry and clinical neuroscience
Adverse alcohol consumption is a major public health concern, which might have been further increased by the COVID-19 pandemic. In this study we investigated the impact of a lockdown stage on the association between alcohol consumption,…
View details →Kim SH, Heo JH, Cunanan K et al. · 2026 · Journal of the Endocrine Society
Context While popular weight-loss medications have raised concerns about lean mass loss, the normative effects of nonpharmacologic weight loss on body composition remain unclear. Objective We assessed how the extent of weight loss from…
View details →Seetahul Y, Greitemeyer T · 2025 · Preprint
Objective: With two experiments (N = 1,576), we examine the causal effect of frustration on the immediate inclination to play violent video games (VVGs) and the moderating role of long-term VVG exposure. Method: Frustration was…
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