Negative / Null Result ReportOpen accessMedicine
Chatila ZK, Duggan MR, Silberberg E et al. · 2026 · Alzheimer's & dementia : the journal of the Alzheimer's Association
While a growing body of literature suggests a role for infections in Alzheimer's disease (AD), microbial contributions to AD remains a contentious topic, in part due to challenges in reconciling the positive evidence with studies reporting…
View details →Negative / Null Result ReportOpen accessMedicine
Helac A, Uchino BN · 2025 · Acta psychologica
General perceived social support is important because it is linked to significant health outcomes. Most research examining perceived social support and health behaviors has not formally modeled the influence of interdependence in a dyad.…
View details →Negative / Null Result ReportMedicine
Sarfraz S, Fouad Elganainy M, Waris U et al. · 2026 · Proceedings (Baylor University. Medical Center)
Background Secondhand smoke (SHS) is a major cardiovascular risk factor, but its relationship with resting tachycardia, a marker of autonomic imbalance and adverse prognosis, remains unclear in young adults. Methods We analyzed adults aged…
View details →Negative / Null Result ReportOpen accessMedicine
Roozenbeek J, Lasser J, Marks M et al. · 2025 · Royal Society open science
The spread of misinformation on social media continues to pose challenges. While prior research has shown some success in reducing susceptibility to misinformation at scale, how individual-level interventions impact the quality of content…
View details →Negative / Null Result ReportOpen accessMedicine
Wei Y, Li J · 2025 · Discover oncology
Background Non-alcoholic fatty liver disease (NAFLD) has been increasingly associated with hepatocellular carcinoma (HCC) risk in observational studies, yet the causal nature of this relationship and its impact on systemic lipid metabolism…
View details →Negative / Null Result ReportOpen accessMedicine
Zhou C, Dong X, Chen G et al. · 2025 · Nature medicine
After the global approval of atezolizumab plus bevacizumab and chemotherapy as first-line metastatic nonsquamous non-small-cell lung cancer (nsqNSCLC) treatment, the IMpower151 ( NCT04194203 ) trial was conducted in China to address…
View details →Negative / Null Result ReportMedicine
Esparragosa Vazquez I, Sanson M, Chinot OL et al. · 2024 · Neuro-oncology advances
Background Based on preclinical studies showing that IDH-mutant (IDHm) gliomas could be vulnerable to PARP inhibition we launched a multicenter phase 2 study to test the efficacy of olaparib monotherapy in this population. Methods Adults…
View details →Abandoned HypothesisOpen accessMedicine
Reynolds GP · 2024 · Journal of psychopharmacology (Oxford, England)
A major effort of the pharmaceutical industry has been to identify and market drug treatments that are effective in ameliorating the symptoms of psychotic illness but without the limitations of the current treatments acting at dopamine D2…
View details →Negative / Null Result Report
Takahara N, Nakai Y, Isayama H et al. · 2022 · Preprint
Purpose: Given the promising activity and tolerability of FOLFIRINOX as a second-line treatment for advanced biliary tract cancer (BTC), it can be an attractive first-line treatment option as well. Materials: and Methods: This is a…
View details →Negative / Null Result ReportOpen accessMedicine
Zumla A, Rosenthal PJ, Sam-Agudu NA et al. · 2025 · The American journal of tropical medicine and hygiene
On August 14, 2024, following a regional declaration by the Africa Centres for Disease Control and Prevention, the World Health Organization declared mpox a Public Health Emergency of International Concern, marking the second such…
View details →Negative / Null Result ReportMedicine
Yuan H, Curran JG, Keith SW et al. · 2021 · Headache
Objective To evaluate the efficacy and safety of intravenous (IV) Ibuprofen for acute treatment of migraine. Background IV nonsteroidal anti-inflammatory drugs (NSAIDs) are an alternative to oral NSAIDs, especially in patients with severe…
View details →Negative / Null Result ReportMedicine
Møller P, Roursgaard M · 2024 · Mutation research. Reviews in mutation research
Humans ingest particles and fibers on daily basis. Non-digestible carbohydrates are beneficial to health and food additives are considered safe. However, titanium dioxide (E171) has been banned in the European Union because the European…
View details →Negative / Null Result ReportOpen accessMedicine
Jin Q, Liu Y, Tong Q et al. · 2025 · Frontiers in nutrition
Objective To examine whether a concise, clinic-feasible Patient Inflammatory Diet Score (PIDS) relates to prevalent pancreatic cancer and cardiovascular disease (CVD) in a hospital population, and to explore associations with systemic…
View details →Negative / Null Result ReportMedicine
Davidenko N, Day J · 2025 · Memory & cognition
Humans' ability to draw faces accurately from memory is extremely rare. One source of difficulty is the drawing process itself, which requires converting a complex, three-dimensional mental representation to a two-dimensional drawing. To…
View details →Negative / Null Result ReportMedicine
Gaskins AJ, Newman AJ, Kawwass JF et al. · 2026 · Environmental research
Background While extreme ambient heat has been associated with several adverse pregnancy and birth outcomes little is known regarding the link between extreme ambient temperatures and human fertility. Objective To evaluate the associations…
View details →Negative / Null Result ReportOpen accessMedicine
van Bree S, Mackenzie AS, Wimber M · 2024 · Imaging neuroscience (Cambridge, Mass.)
The application of multivariate pattern analysis (MVPA) to electroencephalography (EEG) data allows neuroscientists to track neural representations at temporally fine-grained scales. This approach has been leveraged to study the locus and…
View details →Negative / Null Result ReportOpen accessMedicine
Sato K, Inoue K, Yamaguchi T et al. · 2025 · JAMA network open
Importance Excess salt intake is a major modifiable risk factor for hypertension and cardiovascular disease. Personalized interventions using genetic information and digital tools, such as smartphone applications, may enhance sodium…
View details →Negative / Null Result ReportOpen accessMedicine
Liu P, Zeng Q · 2025 · Journal of multidisciplinary healthcare
Background The causal relationship between HIV infection and insulin resistance, as well as diabetes mellitus, remains uncertain. This study explores these associations using genome-wide association study data and Mendelian randomization…
View details →Negative / Null Result ReportOpen accessMedicine
Shaaban M, Ryan JT, Adediran E et al. · 2026 · F&S reports
Objective To study whether incident endometriosis diagnosis, staging, and typology are associated with concurrent elevated serum inflammatory markers interleukin-6 (IL-6), interleukin-8 (IL-8), and tumor necrosis factor alpha (TNF- α ).…
View details →Negative / Null Result Report
Levy H, Naples A, Collett S et al. · 2023 · Preprint
Individuals with hoarding disorder (HD) have difficulty parting with personal possessions, which leads to the accumulation of excessive clutter. According to a proposed biphasic neurobiological model, HD is characterized by blunted central…
View details →Negative / Null Result ReportOpen accessMedicine
Zebarjadi N, Kluge A, Adler E et al. · 2024 · eNeuro
The study of ideological asymmetries in empathy has consistently yielded inconclusive findings. Yet, until recently these inconsistencies relied exclusively on self-reports, which are known to be prone to biases and inaccuracies when…
View details →Negative / Null Result ReportOpen accessMedicine
Anettová L, Šipková A, Cibulka P et al. · 2025 · Parasitology research
This study summarizes the findings of a comprehensive field investigation into the presence of Angiostrongylus cantonensis, a zoonotic nematode responsible for meningitis, in selected regions of the eastern Mediterranean. Samples were…
View details →Negative / Null Result ReportOpen accessMedicine
O'Connell SR, Wilson GE, Berkowitz DH et al. · 2026 · Imaging neuroscience (Cambridge, Mass.)
Groove is the pleasurable urge to move to the beat of music, a universally experienced human phenomenon. Because listeners are often inspired to move to music with groove, we asked whether high-groove music would promote greater motor…
View details →Negative / Null Result ReportMedicine
Colbeth HL, Riddell CA, Thomas M et al. · 2024 · Journal of epidemiology and community health
Background Structural racism's influence on workforce policies and practices presents possible upstream targets for assessing and reducing racial health disparities. This study is the first to examine workforce racial diversity in…
View details →Negative / Null Result ReportMedicine
Miller AL, Zhao Y · 2023 · Physical review letters
Over 10 years ago, Fermi observed an excess of GeV gamma rays from the Galactic Center whose origin is still under debate. One explanation for this excess involves annihilating dark matter, another requires an unresolved population of…
View details →Negative / Null Result ReportOpen accessMedicine
King M, Bruinsma S, Ivry RB · 2024 · Neurobiology of language (Cambridge, Mass.)
Cerebellar involvement in language processing has received considerable attention in the neuroimaging and neuropsychology literatures. Building off the motor control literature, one account of this involvement centers on the idea of…
View details →Negative / Null Result ReportOpen accessMedicine
Obara-Gołębiowska M · 2026 · Eating and weight disorders : EWD
Purpose To identify person-centered psychological profiles of eating-related risk based on early maladaptive schemas (EMS), emotion regulation difficulties, and eating behaviors, and to examine their external validation using…
View details →Negative / Null Result ReportOpen accessMedicine
Bjørkheim SB, Hystad SW, Sætrevik B · 2026 · PeerJ
The way people perceive health risks is often assumed to influence how they adopt precautionary measures. However, people's assessment of a given phenomenon's risk may vary over time, and the relationship between perceived risk and…
View details →Negative / Null Result ReportOpen accessMedicine
Kracht CL, Falkenhain K, Flanagan EW et al. · 2026 · JMIR mental health
Background Household chaos is an emerging risk factor for childhood obesity development, especially in families with lower socioeconomic status (SES). It is unclear if changes in household chaos, especially in pregnancy, may mediate the…
View details →Negative / Null Result ReportOpen accessMedicine
Neelam P, Sowndarya K, Anupama H et al. · 2025 · Advanced biomedical research
Background Homocysteine (Hcy) and dyslipidemia are established risk parameters of atherosclerosis. Considerable research has been conducted using ratios of lymphocytes to other cellular components of the peripheral white blood cell count…
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