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WASTE Journal

Browse the failure-mode index

21,770 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Impact of application repetition on Joule heating and lesion formation using a circular-shaped pulsed field catheter.

Okumura M, Yamagami S, Akiyama M et al. · 2026 · Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

Introduction Pulsed field ablation (PFA) is a non-thermal ablation modality, but repeated high-voltage applications can still cause Joule heating at the electrode-tissue interface. We evaluated the effects of application repetition and…

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Negative / Null Result ReportMedicine

Clinical study of the superthin anterolateral thigh flap for reconstruction of post-traumatic ankle joint soft-tissue defects.

Xiang F, Lin J, Chen B et al. · 2026 · The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons

Background To compare the superthin (3-5 mm) versus conventional (≥10 mm) anterolateral thigh (ALT) flap for post-traumatic ankle reconstruction. Methods Retrospective cohort (2020-2024): superthin ALT (n=26) vs conventional ALT (n=34).…

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Negative / Null Result ReportMedicine

Exploring iridotrabecular contact index and related factors in primary angle closure disease: a swept-source anterior segment OCT study.

Jeong Y, Park KH, Jeoung JW · 2026 · The British journal of ophthalmology

Background/aims This study evaluates the relationship between the iridotrabecular contact (ITC) index and various anterior segment parameters, with a particular focus on lens-related parameters, given their clinical relevance in primary…

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Negative / Null Result ReportOpen accessMedicine

Lamotrigine serum concentrations as longitudinal biomarkers for seizure risk prediction in pregnant women with epilepsy: a secondary analysis of the EMPiRE study.

Allotey J, Junaid F, Peréz T et al. · 2026 · BMJ neurology open

Background Serum lamotrigine concentrations fall during pregnancy, and therapeutic drug monitoring is often used to guide dose adjustment. We do not know whether serial antenatal measurements improve prediction of seizure risk in pregnant…

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Negative / Null Result Report

Addressing Unanswered Questions About the Shift of Strategy Approach: A Multi-Study Investigation of Approach Variations, Repeated Interviews, and Innocent Versus Guilty Responses

Nyström L, Granhag A, Neofotistos E et al. · 2026 · Preprint

Introduction. The Shift-of-Strategy (SoS) approach aims to obtain concealed information from semi-cooperative suspects by prompting them to shift toward more forthcoming counter-interrogation strategies. While previous studies on the…

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Negative / Null Result ReportMedicine

IgA nephropathy occurrence, treatment, and prognosis in the last two decades in Denmark.

Ystrøm IK, Jensen SK, Andersen IT et al. · 2026 · Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

Background and hypothesis IgA nephropathy (IgAN) is the leading cause of primary glomerulonephritis; however, reported incidences and prevalences vary substantially across countries. This study assessed the epidemiology of IgAN including…

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Negative / Null Result ReportMedicine

Intravenous IRON supplementation in Heart Failure with Preserved Ejection Fraction and iron deficiency (IRON-HFpEF): a comprehensive phase II multicentre placebo-controlled randomised clinical trial.

van de Bovenkamp AA, Nassiri S, de Man FS et al. · 2026 · European journal of heart failure

Aims Iron deficiency (ID) is common in patients with heart failure with preserved ejection fraction (HFpEF). The IRON-HFpEF trial aimed to evaluate the mechanistic effects of intravenous iron supplementation on cardiovascular function and…

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Negative / Null Result ReportMedicine

Evaluation of a structured type 1 diabetes education program for adolescents and parents: Teens Empowered to Actively Manage Type 1 (TEAM T1).

Hagger V, Hendrieckx C, Cotterill A et al. · 2026 · Diabetic medicine : a journal of the British Diabetic Association

Aim To examine changes in psychological and clinical outcomes among adolescents and parents after structured type 1 diabetes education delivered in routine care. Methods Teens Empowered to Actively Manage Type 1 Diabetes (TEAM T1) is a…

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Negative / Null Result ReportMedicine

Prophylactic cavotricuspid isthmus ablation in addition to pulmonary vein isolation is associated with improved recurrence-free survival in patients aged > 70 years with paroxysmal atrial fibrillation.

Li JL, Wu JH, Zhao X et al. · 2026 · Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

BACKGROUND: The role of prophylactic cavotricuspid isthmus (CTI) ablation remains controversial in atrial fibrillation (AF) patients without atrial flutter (AFL). Given the strong association between AF, AFL, and age, this study aimed to…

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Negative / Null Result ReportOpen accessMedicine

Effect of short-term supplemental oxygen therapy on 6-min walk distance in highlanders at risk for pulmonary hypertension: a randomised, crossover trial.

Hertig D, Furian M, Müller J et al. · 2026 · ERJ open research

Background Little is known about the effects of portable supplemental oxygen therapy (SOT) to improve exercise performance in highlanders at risk for high-altitude pulmonary hypertension (HAPH). We aimed to investigate whether SOT improves…

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Negative / Null Result ReportMedicine

Effects of propionic acid inclusion and ensiling time on in situ ruminal starch degradability of high-moisture flint corn grain silage.

Martins BM, Vieira RAM, Bittencourt CS et al. · 2025 · Journal of dairy science

This study evaluated the effects of propionic acid inclusion (PAI; 0, 0.25, and 0.50% of fresh matter) and ensiling time (ENT; 30, 60, 90, 120, 150, and 180 d) on the chemical composition, fermentation profile, DM losses, and in situ…

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Negative / Null Result ReportMedicine

Postoperative Radiotherapy May Improve Survival in Certain Patients with pN2 Non-Small Cell Lung Cancer Who Do Not Have Extranodal Extension.

Jeon SH, Song C, Jeon JH et al. · 2026 · Cancer research and treatment

Purpose The aim of this study was to identify subgroups of patients with pathologic N2 (pN2) non-small cell lung cancer (NSCLC) who may benefit from postoperative radiotherapy (PORT). Particular attention was given to evaluating whether…

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Negative / Null Result ReportMedicine

Comparing Clinical and Radiological Outcomes for a Three-Dimensional Printed Highly-Porous Cup and a Hydroxyapatite-Coated Non-Highly-Porous Cup in Total Hip Arthroplasty Using Propensity Score Matching.

Okazaki T, Imagama T, Matsuki Y et al. · 2026 · The Journal of arthroplasty

Background The use of highly-porous acetabular components in total hip arthroplasty (THA) has gained popularity. To elucidate the clinical and radiological outcomes of three-dimensional (3D)-printing highly porous cups, we compared…

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Negative / Null Result ReportMedicine

Hamstring-to-quadriceps ratio across menstrual cycle phases in physically active women: a repeated-measures study.

Heinrich C, Hofstaetter H, Puschkasch-Möck S et al. · 2026 · European journal of applied physiology

Objective To evaluate conventional hamstring-to-quadriceps ratio across the menstrual cycle in distinct angular velocities in an eumenorrheic, physically active population. Design Repeated measures within-subjects design. Methods…

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Negative / Null Result ReportMedicine

Medium Cut-Off Versus High-Flux Dialyzers and Changes in Beck Depression Inventory Scores in Maintenance Hemodialysis: An Exploratory Observational Study.

Avsar FN, Erinc O, Sahutoglu T · 2026 · Hemodialysis international. International Symposium on Home Hemodialysis

Introduction Depression is prevalent in maintenance hemodialysis patients and is influenced by the interplay of physical and mental health. Rather than a direct antidepressant effect of dialyzer membrane type, improved clearance of middle…

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Negative / Null Result ReportMedicine

Acute cholecystitis in the robotic era: comparative safety and feasibility of robotic and laparoscopic cholecystectomy in an acute care surgery service.

Pontecorvo AA, Cornejo J, Tsenteradze T et al. · 2026 · Journal of robotic surgery

This study aimed to evaluate and compare perioperative outcomes of robotic versus laparoscopic cholecystectomy in patients with acute cholecystitis within an Acute Care Surgery setting. A retrospective cohort study was conducted including…

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