21,742 real negative results, null findings, and replication failures. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Hunter JWS, Van Den Heuvel C, Stephenson L et al. · 2025 · The American journal of forensic medicine and pathology
Abstract Both obesity and opioid abuse are increasing in numbers globally. As these entities may be associated with significant respiratory compromise, it was hypothesized that synergism may occur and that as a result of this obese…
View details →Christian K, Moritz C, Skelton K et al. · 2024 · Preprint
1. Reptiles are challenged with maintaining stable hydric states and viable body temperatures in a variable terrestrial environment. Reptiles can use behaviour to select favourable microhabitats as well as physiological adaptations, such…
View details →Eskandarian S, Zafarani A, Tandel P et al. · 2025 · Molecular biology reports
Background Clopidogrel is a widely used antiplatelet drug for treating acute coronary syndrome. Its metabolism primarily involves the CYP2C19 isoenzyme, with CYP2C192 and CYP2C193 alleles associated with reduced metabolic activity.…
View details →Dias ALB, Nascimento JR, Brito-Sousa JD et al. · 2025 · PloS one
Background Glucose-6-phosphate dehydrogenase deficiency (G6PDd) is a common genetic disorder that impairs the cellular antioxidant response and has been hypothesized as a potential risk factor for severe outcomes in viral infections,…
View details →van Dijkman SC, Félices M, Pandurangavittal B et al. · 2026 · British journal of clinical pharmacology
Aims Paroxetine is a selective serotonin reuptake inhibitor (SSRI), approved for treatment of major depressive disorder and anxiety disorders. Some SSRIs are known to prolong the QT interval; however, clinical evidence to establish a lack…
View details →Soffer GK, Feinberg T, Kroll H et al. · 2025 · The Journal of asthma : official journal of the Association for the Care of Asthma
Objectives To assess the prevalence and perceived efficacy of complementary and alternative medicine (CAM) use among urban adolescents with asthma, building on a previous landmark study, and to determine if CAM use varied by asthma…
View details →Zhou C, Cui GY, Tang YH et al. · 2025 · World journal of diabetes
Background The association between ambient air pollution and glycolipid metabolic disorders (GMDs, including diabetes mellitus and dyslipidemia) is still not well understood, especially when it comes to the different effects of long-term…
View details →Mayntz SP, Warncke S, Ladefoged LG et al. · 2025 · Journal of cardiology
Background Cardiovascular disease is a leading cause of mortality globally, with air pollution, particularly fine particulate matter (PM 2.5 ), recognized as a significant risk factor. While long-term accumulated exposure to PM 2.5 has…
View details →Plischuk M, Garizoain G, Mancuso RG · 2025 · International journal of paleopathology
Objective This study examines how age at death, sex, and socio-historical context relate to the frequency, location, and severity of Schmorl's nodes. Materials The sample comprised thoracic and lumbar vertebrae of 192 skeletons from two…
View details →Ekrami A, Taheri B, Daneshfar S et al. · 2025 · BMC infectious diseases
BACKGROUND: So far, few studies have examined the association between CRISPR-Cas and antibiotic resistance in Shigella isolates. Hence, this study sought to address this issue in Shigella species isolated from stool samples of patients…
View details →Alharethi R, Knight S, Luikart HI et al. · 2024 · Clinical transplantation
Cardiac allograft vasculopathy (CAV) is a leading cause of death after heart transplantation (HT). We evaluated donor-derived cell-free DNA (dd-cfDNA) as a noninvasive biomarker of CAV development after HT. The INSPIRE registry at the…
View details →Vidal SI, Silverberg JI · 2024 · Archives of dermatological research
Background Asthma is one of the most well-recognized comorbidities of atopic dermatitis (AD). However, the relationship of AD severity and morphology with asthma characteristics in adults is not well defined. Objectives To understand…
View details →Maclennan APH, Sitner-Medvedovsky E, Varon D et al. · 2024 · Oxford medical case reports
Supraventricular tachycardia (SVT) is a narrow QRS complex tachyarrhythmia with a heart rate above 220 beats per minute in infants and children. Ventricular tachycardia can be due to electrolyte abnormalities, cardiomyopathies, congenital…
View details →Normann SS, Andersen HR, Lund LC et al. · 2025 · Environmental Research
Over the past decade, the use of organophosphate insecticides including chlorpyrifos has faced increasing restrictions due to health concerns, leading to a rise in use of pyrethroids. Concerns about neurodevelopmental insults following…
View details →Sotoudeheian M · 2024 · Preprint
Aim: This study aimed to explore the correlation between the FIB-5 and FIB-4 indices, which assess liver fibrosis, and the grouped duration of heart failure (HF) in a cohort of subjects from the National Health and Nutrition Examination…
View details →Biersma AGW, van Leer B, Renes MH et al. · 2026 · BMC nephrology
BACKGROUND: Kidney function is associated with kidney volume. This study aims to explore automated segmentation for measuring total kidney volume (TKV) and to analyse the association between (changes in) TKV and acute kidney injury (AKI)…
View details →Ahuja S, Dubey A, Zaheer S · 2024 · Korean journal of clinical oncology
Purpose Endometrial cancer (EC) ranks as one of the most prevalent gynecological malignancies globally. The presence and role of stromal tumor-infiltrating lymphocytes (TILs) in the tumor microenvironment have garnered interest due to…
View details →Godina E, Khromov-Borisov N, Bondareva E · 2025 · Journal of physiological anthropology
Background Prediction of sports success (sports talent) based on individual genetic characteristics is the main goal of sports genetics/genomics. Most often, markers of predisposition to speed-strength sports, or endurance, are…
View details →El Shahed A, Chau V, Terry J et al. · 2025 · Pediatric research
Aim To determine the relationship between presumed preterm birth (PTB) etiology and the incidence of brain injury, and neurodevelopmental outcomes at 3 and 4.5 years. Subjects and methods Prospective cohort study including 222 neonates…
View details →Toklu E, Göknar G, Adıyeke SK · 2026 · BMC ophthalmology
BACKGROUND: Idiopathic epiretinal membrane (iERM) is a common age-related vitreoretinal disorder characterized by fibrocellular proliferation on the inner limiting membrane. Although systemic inflammation has been suggested to play a…
View details →Schiemer C, Horswill MS, Hill A et al. · 2025 · Journal of safety research
Introduction As the medically prescribed use of cannabis flower continues to increase, there is a need to understand how vaporized cannabis can acutely affect driving-related skills and risk-taking behaviors in medicinal populations.…
View details →Yang Y, Li Z, Zhu Y et al. · 2025 · Diagnostic pathology
Background Triple-negative breast cancer (TNBC) is aggressive and has limited therapeutic options due to the absence of targeted therapies, highlighting the urgent need for prognostic biomarkers linked to cancer stemness and…
View details →Kobayashi S · 2025 · World journal of hepatology
Carteri et al reaffirmed the value of the Child-Turcotte-Pugh score in predicting survival in patients with cirrhosis. However, the lack of association with nutritional markers warrants careful interpretation. In cirrhosis, complex…
View details →Yigit S, Nursal AF, Celik A et al. · 2024 · Revista da Associacao Medica Brasileira (1992)
Objective Coronary artery disease is the leading cause of death worldwide. Vascular endothelial growth factor is known to induce endothelial cell migration and proliferation, increase vascular permeability, and modulate thrombogenicity.…
View details →Takanaga S, Matsumoto N, Kadowaki T et al. · 2024 · Acta medica Okayama
Kawasaki disease (KD) is a pediatric disease of unknown etiology that commonly affects infants in East Asia. Infants born small for gestational age (SGA) have weaker immune systems and are more susceptible to infection. Using data from a…
View details →Yang X, Liu W, Mao Z et al. · 2026 · GigaScience
Background Preeclampsia is a severe pregnancy complication that threatens maternal and neonatal health and well-being. Previous studies on epigenome-wide association studies (EWAS) of preeclampsia produced inconsistent results in cord…
View details →Alroba R, Alfakhri A, Badreldin H et al. · 2024 · Pharmacoepidemiology and drug safety
Purpose Previous research and pharmacovigilance monitoring activities have suggested a potential association between indapamide use and rhabdomyolysis. This study aims to investigate the potential causal relationship between the use of…
View details →Barcia Aguilar C, Amengual-Gual M, Brenton JN et al. · 2024 · Seizure
Purpose Evaluate the relationship between first and second-line medication dosing and progression to refractory status epilepticus (RSE) in children. Methods This is a retrospective analysis of prospectively collected data from September…
View details →Bhushan A, Dexter F, Brindeiro C et al. · 2026 · Anesthesiology and perioperative science
Purpose Earlier, patients developed surgical site infection for 2.0% of cases without Staphylococcus aureus transmission through anesthesia work areas, 11% with S. aureus transmitted susceptible to prophylactic antibiotic, and 18% with…
View details →Khoja R, Catuna TD, Gussin GM et al. · 2026 · Infection control and hospital epidemiology
Residual chlorhexidine gluconate (CHG) skin concentrations are thought to improve disease prevention. In the Changing Lives by Eradicating Antibiotic Resistance (CLEAR) trial, posthospitalization decolonization of MRSA carriers reduced…
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