Negative / Null Result ReportMedicine
Aljarallah S, Aldeligan SH, Almarshed A et al. · 2026 · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
PURPOSE.: Restless legs syndrome (RLS) is a common but under-recognised non-motor symptom in multiple sclerosis (MS), potentially linked to central nervous system lesion distribution. This study aimed to assess the anatomical distribution…
View details →Negative / Null Result ReportMedicine
Yıldız P, Yurtseven A, Turan C et al. · 2026 · BMC pharmacology & toxicology
Methylphenidate is widely prescribed for attention-deficit/hyperactivity disorder, and its use has increased substantially in recent years. Although generally considered safe within therapeutic ranges, supratherapeutic ingestion may result…
View details →Negative / Null Result ReportMedicine
Haksever M, Taşdemir D · 2026 · BMC pregnancy and childbirth
To evaluate the association between maternal hemoglobin and ferritin levels and fetal cortical maturation assessed by neurosonography between 30 and 34 weeks of gestation. This prospective observational study included 187 singleton…
View details →Negative / Null Result ReportOpen accessMedicine
Kaushik A, Jaiswal A, Priya B et al. · 2025 · Journal of family medicine and primary care
Background Breast cancer is the most common cancer in women across the world. Immune cells can detect and destroy cancer cells. However, cancer cells acquire certain immune evasion mechanisms such as PD-1+ T-cells, to combat immune…
View details →Negative / Null Result ReportOpen accessMedicine
Zhou X · 2026 · Translational psychiatry
Low titers of blood circulating natural anti-NMDAR1 autoantibodies were reported in ~10% of the general human population. Their potential effects on NMDAR functions in the brain, however, remain unknown. We developed a new method to more…
View details →Negative / Null Result Report
Isikoglu BD, Senler FC · 2026 · Preprint
Abstract Purpose. Insomnia is a heterogeneous symptom cluster of multiple etiologies, frequently encountered in oncology patients, and chemotherapy has been implicated as a contributing factor. We aimed to evaluate the effects of…
View details →Negative / Null Result Report
Coban S, Yavuz S, Dogan C et al. · 2026 · Preprint
Abstract Background Emergency department overcrowding is a persistent global public health issue, often driven by non-urgent visits. Health literacy is considered a key determinant of appropriate healthcare utilization. Objective This…
View details →Negative / Null Result ReportMedicine
Önder N, Muratoglu K · 2026 · Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment
Peanuts are among the most clinically important food allergens and may cause severe reactions even at very low exposure levels. This study investigated the presence of peanut residues in packaged baby biscuits marketed on the European side…
View details →Negative / Null Result Report
Zeng Y, Zhu Y, Liu W et al. · 2026 · Preprint
Abstract Background When the function of one kidney is impaired or lost, the contralateral kidney may exhibit varying degrees of compensatory response. However, the influencing factors and underlying mechanisms of renal compensation remain…
View details →Negative / Null Result Report
Ntombana L, Dlatu N, Hosu MC · 2026 · Preprint
Background: /Objectives: The growing burden of multidrug-resistant tuberculosis (MDR-TB), driven by poor treatment adherence and limited diagnostic access, has complicated disease control efforts. The recent introduction of shorter, less…
View details →Negative / Null Result ReportMedicine
Mirmosayyeb O, Barzegar M, Rezaei M et al. · 2026 · Neurologia
Purpose Multiple sclerosis (MS) is a debilitating disease accompanied by physical and mental comorbidities. Little is known about the relation between different comorbidities and health-related quality of life (HRQOL) in people with MS…
View details →Negative / Null Result Report
Kumar MC, Ashok A · 2026 · Preprint
Abstract Background Cardiovascular diseases (CVDs) remain the leading cause of mortality globally. Cardiac rehabilitation (CR) is an effective intervention to improve recovery and reduce recurrence; however, nurses’ knowledge and attitude…
View details →Negative / Null Result ReportMedicine
Kanani P, Shinde V, Bhimani K et al. · 2026 · Annals of African medicine
Background Shock is a critical, life-threatening syndrome defined by a state of global hypoperfusion that results in inadequate oxygen and nutrient delivery to tissues, leading to cellular dysfunction and ultimately, organ failure. Despite…
View details →Negative / Null Result ReportOpen accessMedicine
Kądziela M, Migdalska-Sęk M, Domańska-Senderowska D et al. · 2026 · International journal of molecular sciences
Vitiligo is a chronic autoimmune skin disorder characterized by progressive melanocyte loss and depigmented skin lesions, whose pathogenesis has been attributed to genetic and immunological factors. The aim of this exploratory study was to…
View details →Negative / Null Result ReportMedicine
Anderson N, Kimlin K, O'Rourke JL et al. · 2026 · Pediatric research
Background Congenital hearing loss can significantly affect childhood development, yet more than half of affected infants present without identifiable risk factors. A possible association between maternal diabetes and congenital hearing…
View details →Negative / Null Result ReportMedicine
Li Y, Zhu YX, Qiu Y et al. · 2026 · Clinical nephrology
Objective The association between the atherogenic index of plasma (AIP) and chronic kidney disease (CKD) among individuals with different metabolic syndromes remains inadequately characterized. The aim of this study is to assess the…
View details →Negative / Null Result ReportMedicine
Mostofi K, Caragliano G · 2026 · The Journal of hospital infection
Background Surgical site infections (SSIs) are a major complication of spinal surgery. The influence of tattoos overlying the operative incision has not been previously evaluated as a risk factor in this context. Methods Retrospective…
View details →Negative / Null Result Report
Chen F, You R, Liu Y et al. · 2026 · Preprint
Background and Aims MASLD has become the most prevalent chronic liver disease globally. Although MVPA and plasma fatty acids have been individually studied in relation to metabolic health, their independent and combined associations with…
View details →Negative / Null Result ReportOpen accessMedicine
Kim T, Oh SB, Choi HJ et al. · 2025 · Genes
Objective Suicide attempts have become one of the most serious problems worldwide in recent years. Suicide attempts are known to be genetically highly associated with serotonin and BDNF in international studies. Methods In this study, we…
View details →Negative / Null Result ReportMedicine
Devi Krishna RB, Mathews SG, Agarwal P et al. · 2026 · Biochemical genetics
To assess the potential association between LRP1 (rs715948) and PAI1 (rs2227631, rs1799889) gene variation and ovarian cancer (OC) susceptibility. This study evaluated the genotypic and allelic distributions of LRP1 gene and PAI1 gene…
View details →Negative / Null Result Report
Ma L, Ma Y, Huang Z et al. · 2026 · Preprint
Abstract Background: Stroke remains a leading cause of death and disability among older adults. Depressive symptoms and low social participation may increase stroke risk via behavioural and biological pathways. This study examined the…
View details →Negative / Null Result ReportOpen accessMedicine
Majmudar IP, Aggarwal S, Hamzeh N et al. · 2026 · Clinical ophthalmology (Auckland, N.Z.)
Purpose To determine if there is an association between surgeon-patient sex concordance and post-surgical complications for cataract surgeries. Patients and methods In this 16-year retrospective cohort study, data was collected from the…
View details →Negative / Null Result ReportMedicine
Foo JF, Haddow K, Jones S et al. · 2026 · The Journal of laryngology and otology
Objectives To investigate whether socioeconomic deprivation is associated with residual or recurrent cholesteatoma following primary mastoidectomy. Methods A retrospective cohort study included all patients undergoing primary mastoidectomy…
View details →Negative / Null Result ReportMedicine
Peng P, Guo Y, Zhu Y · 2026 · Advances in clinical and experimental medicine : official organ Wroclaw Medical University
Background Given that long-term anticoagulant therapy is required in many clinical scenarios, continuous safety monitoring of direct factor Xa inhibitors is of great importance. To date, the renal safety of these agents remains a subject…
View details →Negative / Null Result ReportMedicine
Zhai L, Fang C, Wang L et al. · 2026 · Scientific reports
There is little evidence about the susceptible exposure window of maternal depression during pregnancy and preterm birth in China. We aimed to assess the trimester-specific association of depression during pregnancy with preterm birth, and…
View details →Negative / Null Result ReportOpen accessMedicine
Metwally YF, Zahran RF, El Sadda RR et al. · 2026 · Discover oncology
Background Lung cancer remains the leading cause of cancer-related deaths worldwide. Despite advances in diagnostics and treatment, most patients are diagnosed at advanced stages. Genetic variants such as single nucleotide polymorphisms…
View details →Negative / Null Result ReportMedicine
Aryal SB, Raj Joshi D · 2026 · Journal of Nepal Health Research Council
Background Homocysteine (Hcy) contributes to oxidative stress and renal injury by generating reactive oxygen species and reducing heme oxygenase-1 levels. Elevated Hcy (Hhcy) may worsen outcomes after acute renal failure(ARF), promoting…
View details →Negative / Null Result ReportMedicine
Bellos I, Marinaki S, Benetou V · 2026 · Journal of clinical medicine
Background/Objectives : Composite endpoints are commonly used in chronic kidney disease (CKD) trials to enhance statistical efficiency but may not reflect clinically meaningful outcomes. We assessed agreement between composite endpoints…
View details →Negative / Null Result ReportMedicine
Pires E Silva C, Malaspina OA, Basting RT · 2026 · General dentistry
Light transmission during photopolymerization is reduced by the intrinsic optical properties of ceramics, which vary with material and thickness. The higher translucency of lithium disilicate contrasts with the chemical inertness and…
View details →Negative / Null Result ReportMedicine
Hakim MS, Hashimi MH, Saeed KM et al. · 2026 · Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit
Background Viral hepatitis and HIV infections are common public health concerns among injecting drug users, however, there is limited evidence on their seroprevalence in Afghanistan. Aim To determine the seroprevalence of hepatitis B,…
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