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Browse the failure-mode index

21,314 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Influence of short bouts of stair climbing on young adults during prolonged sitting on posture, discomfort, and musculoskeletal performance outcomes: a counterbalanced pilot randomised crossover trial.

Raj AK, Pedersen SJ, Mainsbridge C et al. · 2024 · Ergonomics

Prolonged sitting is postulated to influence musculoskeletal performance (cervical flexor endurance, balance, and agility), discomfort and alter cervical spine angles during work-based computer use. Stair climbing breaks may be a great…

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Failed Experiment ReportOpen accessMedicine

Rumen-protected lysine and methionine failed to improve the performance of late-nursing Awassi ewes regardless of dietary protein contents.

Awawdeh MS · 2024 · Journal of advanced veterinary and animal research

Objective The current study investigated the effects of supplying ruminally protected amino acids (AA) (lysine, L; and methionine, M) and dietary protein levels on the performance of late-nursing ewes. Materials and methods Thirty-one…

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Negative / Null Result ReportMedicine

Factors Influencing Nursing Students' Attitudes and Career Interests in Mental Health Nursing - An Integrative Review.

Cearns K, Lazarus ER, Wahid R · 2026 · The Canadian journal of nursing research = Revue canadienne de recherche en sciences infirmieres

BackgroundMental health nurses represent only 1.03% of the global nursing workforce, contributing to persistent workforce shortages. Undergraduate nursing students demonstrate limited interest in mental health nursing (MHN), often…

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Negative / Null Result ReportMedicine

An Assessment of the Impacts of Feeding Four Fungal Extracts on the Lifespan and Midgut of Newly Emerged Carniolan Honey Bees (<i>Apis mellifera carnica</i>).

Ansaloni LS, Domingues CEC, Gregori M et al. · 2026 · Insects

Given the current global agricultural system, honey bees are exposed to a complex network of stressors that can act simultaneously, making it challenging to maintain healthy colonies. Therefore, studies on natural products to improve…

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Failed Experiment ReportMedicine

Extramedullary infiltration in pediatric acute myeloid leukemia: Results from the Therapeutically Applicable Research to Generate Effective Treatments (TARGET) initiative.

Li W, Shi M, Zhou P et al. · 2024 · Pediatric blood & cancer

Background The outcome of extramedullary infiltration (EMI) in pediatric acute myeloid leukemia (AML) is controversial, and little is known about the implications of stem cell transplantation (SCT) and gemtuzumab ozogamicin (GO) treatment…

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Negative / Null Result ReportMedicine

Effects of walnut consumption for 2 years on older adults' bone health in the Walnuts and Healthy Aging (WAHA) trial.

Oliver-Pons C, Sala-Vila A, Cofán M et al. · 2024 · Journal of the American Geriatrics Society

Background Nutritional strategies to maintain bone health in aging individuals are of great interest. Given the beneficial nutrient composition of walnuts, rich in alpha-linolenic (the vegetable n-3 fatty acid) and polyphenols, their…

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Replication FailureOpen access

Cost-effectiveness of a Victim Improvement Package (VIP): A Randomised Controlled Trial for the Reduction of Continued Symptoms of Depression or Anxiety in Older Victims of Community Crime

Panca M, Serfaty M, Satchell J et al. · 2025 · Preprint

Abstract Background : Crime has significant impact on older victims. High rates of anxiety and depression may be associated with crimes. Aims: This paper aims to evaluate the cost-effectiveness of a Victim Improvement Package (VIP) for the…

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Negative / Null Result ReportOpen accessMedicine

High-fat diet-induced obesity impairs endothelium-dependent relaxation in rabbits: association with MLCK upregulation and partial <i>ex vivo</i> improvement by ML-7.

Li J, Zhou J, Ha Q et al. · 2026 · Frontiers in cardiovascular medicine

Objective Obesity is an independent risk factor for cardiovascular diseases and elevated mortality, yet the underlying mechanisms remain incompletely understood. Impaired endothelium-dependent relaxation is an early manifestation of…

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Replication FailureMedicine

A Comprehensive Assessment of Acute Stroke Care: Delays, Treatment Patterns, and Barriers to Timely Intervention.

Zaidi S, Zoya M, Ishrat M et al. · 2026 · Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

The study aimed to evaluate delays in emergency department (ED) arrival among stroke patients and to identify demographic factors that contribute to these delays. It was a cross-sectional study conducted at the Department of Neurology,…

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Replication FailureMedicine

Peak inspiratory flow in Austrian patients with asthma and/or COPD using dry powder inhalers- a cross-sectional, observational real-world study.

Rowhani M, Hörmannstorfer-Fessl K, Kastner M et al. · 2026 · Respiratory medicine

Background Dry powder inhalers (DPIs) prescribed for respiratory diseases require patients to generate sufficient peak inspiratory flow (PIF) for optimal drug delivery to the airways. However, information is scarce regarding PIF of asthma…

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