21,300 real negative results, null findings, and replication failures. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Li L, Wang Y, Du Z et al. · 2026 · Metabolism: clinical and experimental
Background and aims Targeting key enzymes in hepatic de novo lipogenesis (DNL) presents a promising strategy for treating hypercholesterolemia. However, the precise regulatory mechanisms governing hepatic DNL remain incompletely…
View details →Petersen Dias A, Orsel K, Gammariello CS et al. · 2025 · Research in veterinary science
Digital dermatitis (DD) is a polymicrobial, multifactorial hoof disorder with an undefined etiology, and existing animal models fail to induce a fast, standardized infection in bovine skin. This study explored bacterial inoculation methods…
View details →Willroth EC, Young G, Ford BQ et al. · 2025 · Psychological science
Certain emotion-regulation strategies (e.g., reappraisal) are associated with better well-being and are therefore seen as adaptive (health-promoting) strategies. However, it is unlikely that any strategy is adaptive regardless of context.…
View details →Argenbright CM, Scully IF, Flores D et al. · 2025 · The journal of pain
Pain is a multidimensional phenomenon, encompassing affective-motivational, cognitive-evaluative, and sensory-discriminative domains. Understanding these components is crucial for effective diagnosis and management, particularly in…
View details →Goldberg SB, Baldwin SA, Flynn AWP et al. · 2026 · Clinical psychological science : a journal of the Association for Psychological Science
While it is known that therapists vary in effectiveness, it is unclear what therapist-level characteristics predict this variation. We conducted a large-scale, preregistered study ( n = 97 therapists from the United States and Canada, n =…
View details →Adinugroho I, Bentall R, Stafford T · 2025 · Preprint
This is the first study to attempt replication of Banas et al (2023) on inoculation messages. The original experiment demonstrated that inoculation messages could stimulate resistance to anti-vaccine conspiracy theories. However, a gap was…
View details →Kakeya H, Umeno Y · 2025 · Preprint
Background Kayano et al. estimated the potential number of COVID-19 cases and deaths in Japan from February 17 to November 30, 2021, in a counterfactual scenario where no vaccination was implemented. Their model predicted 63.3 million…
View details →Stawiany K, Kozak K, Sokołowska Z · 2025 · Preprint
The study explores the hypothesis that individuals show greater sympathy towards coherent name-face pairs compared to incoherent pairs, replicating the effect observed by Barton and Halberstadt. A structured questionnaire was designed…
View details →Beldi L, Dong Y, Volet C et al. · 2025 · Preprint
Secondary bile acids, generated through microbial transformation of primary bile acids secreted in bile, play a role in shaping intestinal microbial communities, modulating host immunity, and regulating energy metabolism. In vitro studies…
View details →Dang YL, Esnault K, Leroi MJ et al. · 2025 · Epilepsy & behavior : E&B
Objective Toxoplasma gondii (T. gondii) seropositivity has been reported to have up to a five-fold increased risk for epilepsy. However, substantial heterogeneity in methodology exists across these studies. Furthermore, other studies…
View details →Vaz F, Silva T, Silva E et al. · 2025 · Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine
Pelvic organ prolapse (POP) limits people's quality of life and is quite common in women, especially with advancing age. As cases increase, there is an urgent need for alternative treatments, especially for severe POP, where options remain…
View details →Pachunka A, Jeffries JB, Karr L et al. · 2024 · Preprint
Interacting with animals can improve health and well-being across the lifespan. Some programs such as 4-H and FFA center around youth interacting with animals, potentially enhancing youth development. Mueller (2014) investigated whether…
View details →Mazza A, Voorrips E, Hughes G et al. · 2024 · Preprint
Daily, we perform activities in the presence of others (e.g., office work). While it's well-established that the mere presence of others can influence our performance, it is less clear whether others' performance, rather than just their…
View details →Tavernier N, Wisniewski D, Brass M · 2024 · Preprint
Over the last 15 years, researchers in psychology asserted that manipulating laypeople’s free will beliefs (FWB) has an impact on various downstream social behaviors (such as cheating). More recently, however, many of these findings failed…
View details →Román-Caballero R, Martín-Arévalo E, Martín-Sánchez PDC et al. · 2024 · Consciousness and cognition
Entrainment theories propose that attention inherently oscillates between moments of attentional enhancement and disengagement. Consequently, perceptual and response benefits have been reported in tasks with a rhythmic structure. In the…
View details →Oddleifson C, Kilgus S, Klingbeil DA et al. · 2025 · Journal of school psychology
The purpose of this study was to conduct a conceptual replication of Pendergast et al.'s (2018) study that examined the diagnostic accuracy of a nomogram procedure, also known as a naive Bayesian approach. The specific naive Bayesian…
View details →Tal A, Mudrik L · 2024 · Journal of experimental psychology. General
The field of consciousness studies has yielded various-sometimes contradicting-accounts regarding the function of consciousness, ranging from denying it has such function to claiming that any high-level cognitive function requires…
View details →Romeas T, Goujat M, Faubert J et al. · 2025 · Psychology of sport and exercise
The impact of domain-general cognitive 'brain' training on improving sports performance is highly debated. This study sought to follow-up on research that showcased the benefits of perceptual-cognitive 3D-Multiple Object Tracking (3D-MOT)…
View details →Román-Caballero R, Martín-Arévalo E, Martín-Sánchez PdC et al. · 2024 · Preprint
Entrainment theories propose that attention inherently oscillates between moments of attentional enhancement and disengagement. Consequently, perceptual and response benefits have been reported in tasks with a rhythmic structure. In the…
View details →Houben M, Rief W, Gärtner T et al. · 2024 · Preprint
Abstract Background: Depression is related to a reduced update of negative expectations in response to positive information. Here, we aimed to replicate that cognitive immunization (a cognitive devaluation of expectation-disconfirming…
View details →Whiteford KL, Baltzell LS, Chiu M et al. · 2024 · Preprint
Musical training has been associated with enhanced neural processing of sounds, as measured via the frequency following response (FFR), implying the potential for human subcortical neural plasticity. We conducted a large-scale multi-site…
View details →Zhou Y, Tse CS · 2025 · The Journal of general psychology
In English, head is associated with rationality and logic, whereas heart is related to feeling and emotionality. In Chinese, these head- and heart-related metaphors also exist. Could these head- and heart-related conceptual metaphors…
View details →Noel M, Suttapitugsakul S, Cummings RD et al. · 2024 · Preprint
Protein O-glycosylation is a critical modification in the brain, as genetic variants in the pathway are associated with both common and severe neuropsychiatric phenotypes. However, little is known about the most abundant type of O-glycan…
View details →Wickenhagen A, Flagg M, Port J et al. · 2024 · Preprint
The emergence of the Omicron lineage represented a major genetic drift in SARS-CoV-2 evolution. This was associated with phenotypic changes including evasion of pre-existing immunity and decreased disease severity. Continuous evolution…
View details →Stüber AT, Heimer MM, Ta J et al. · 2025 · European journal of radiology
This study investigates the predictive capability of radiomics in determining programmed cell death ligand 1 (PD-L1) expression (>=1%) status in non-small cell lung cancer (NSCLC) patients using a newly collected [18F]FDG PET/CT dataset.…
View details →Centorame G, Warrington NM, Hemani G et al. · 2024 · Preprint
Background Breastfeeding is hypothesised to benefit child health and cognitive functioning by providing long-chain polyunsaturated fatty acids (LC-PUFA), which are essential for brain development. In 2007, Caspi et al. found evidence in…
View details →Wiesing M, Zimmermann E · 2023 · Preprint
Intentional actions produce a temporal compression between the action and its outcome, known as intentional binding. However, Suzuki et al. (2019) recently showed that temporal compression can be observed even without intentional actions.…
View details →Lloyd B, Wurm F, de Kleijn R et al. · 2023 · Preprint
Background Transcutaneous auricular vagus nerve stimulation (taVNS) is a promising brain stimulation method for the treatment of pharmaco-resistant epilepsy and depression. Its clinical efficacy is thought to depend on taVNS-induced…
View details →Ahrens A, Liesefeld HR, Kinner J et al. · 2026 · Psychological research
In everyday life, we often generalize previously learned associations between our actions and their outcomes to novel, but similar situations. The present study aimed to conceptually and directly replicate results reported by Esser et al.…
View details →Wentura D, Gurbuz E, Paulus A et al. · 2023 · Journal of experimental psychology. Human perception and performance
When asked to judge or react to a facial emotional display of a person, people do not only take the emotion into account, but also other socially important features of the face, such as, for example, ethnicity (Kozlik & Fischer, 2020;…
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