Negative / Null Result ReportMedicine
Gezer, Demir · 2026 · Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES
Traumatic posterior meniscal root tears disrupt normal load transmission, resulting in meniscal extrusion and accelerated osteoarthritis. Although transtibial pull-out repair is widely used, creation of a 4.5-mm tibial tunnel at the joint…
View details →Negative / Null Result ReportMedicine
Ito, Spellman, Khan et al. · 2026 · Paediatric anaesthesia
In pediatric-aged patients, distributive (vasoplegic) shock is commonly caused by sepsis, anaphylaxis, or the humoral/immunologic response following cardiopulmonary bypass. In general, the first-line vasoactive agent for children is…
View details →Negative / Null Result ReportMedicine
Mohamed, Alharbi, Alanazi et al. · 2026 · Cureus
Internuclear ophthalmoplegia (INO) is a distinct ocular motility disorder localizing to the medial longitudinal fasciculus (MLF). Because the MLF is a microscopic, highly myelinated tract, small inflammatory lesions can cause significant…
View details →Negative / Null Result ReportMedicine
Mohamed, Farah, Elhamaky et al. · 2026 · Radiology case reports
Inferior vena cava (IVC) filter penetration is an increasingly recognized complication, particularly after prolonged dwell time or failed retrieval. Although often asymptomatic, multidirectional penetration into adjacent structures may…
View details →Failed Experiment ReportMedicine
Abukhalaf, Al-Ihribat, Sabarna et al. · 2026 · International journal of surgery case reports
Pancreaticoduodenal artery (PDA) pseudoaneurysms are rare vascular complications, accounting for approximately 2% of all visceral artery aneurysms. They are often associated with chronic pancreatitis and have a high risk of rupture, which…
View details →Negative / Null Result ReportMedicine
Niu, Liu, Sun et al. · 2026 · Journal of nanobiotechnology
Urethral reconstruction often fails due to the foreign body reaction (FBR) triggered by the graft, leading to chronic inflammation, fibrosis, and lumen obstruction. To address this challenge, we developed an innovative strategy: a…
View details →Negative / Null Result ReportMedicine
Ciani Berlingeri, Phillips, Mejia Bibriesca et al. · 2026 · The Journal of neuroscience : the official journal of the Society for Neuroscience
The mammalian vestibular system has two types of sensory receptors (hair cells), type I and type II. Understanding the roles of type I and II hair cells in the vestibular system's control of motor behaviors is difficult because most…
View details →Negative / Null Result ReportMedicine
Chen, Yang, Liu et al. · 2026 · Journal of hazardous materials
Assessing water quality comprehensively is crucial for predicting environmental risks. However, existing toxicity assessments are limited to specific physiological processes or reference organisms, failing to capture holistic hazards. Here…
View details →Negative / Null Result ReportMedicine
Liao, Xiang, Chen et al. · 2026 · PloS one
The neutrophil-to-lymphocyte ratio (NLR) has shown inconsistent prognostic value in individuals with sepsis. This study aimed to clarify its ability to predict 28-day mortality via a machine learning-based analysis of a large ICU database.…
View details →Negative / Null Result ReportMedicine
Ippoliti, Gori, Coscarella et al. · 2026 · Skin health and disease
Abrocitinib, a selective Janus kinase 1 (JAK1) inhibitor, has demonstrated efficacy in moderate-to-severe atopic dermatitis (AD), although data in patients whose AD is resistant to multiple systemic therapies remain limited. We report the…
View details →Failed Experiment ReportMedicine
Terry, Isenberg, Gomoll et al. · 2026 · Video journal of sports medicine
Multifocal cartilage defects about the knee have become increasingly prevalent. When left untreated, these injuries may progress to diffuse knee osteoarthritis. Operative management for patients with multifocal chondral defects typically…
View details →Failed Experiment ReportMedicine
Wang, Yu · 2026 · SAGE open medical case reports
A 5-month-old infant presented with paroxysmal crying and vomiting for more than 4 h. Ultrasonography confirmed intussusception in the right abdomen, but intraluminal gas limited precise classification. On the assumption of…
View details →Negative / Null Result ReportMedicine
Puppala, Chodavarapu, Sami et al. · 2026 · Indian journal of orthopaedics
Femoral head impaction injuries, sometimes referred to as the "Hill-Sachs lesion" of the femoral head, are an uncommon yet significant consequence of posterior hip dislocations. These occur due to compressive forces on the femoral head,…
View details →Negative / Null Result ReportMedicine
Gan, Abu Hassan, Tan et al. · 2026 · Therapeutic advances in neurological disorders
Acute attacks of aquaporin-4 antibody neuromyelitis optica spectrum disorder (AQP4-Ab NMOSD) are typically managed with intravenous methylprednisolone, with therapeutic plasma exchange (PLEX) reserved for severe episodes. Despite these…
View details →Negative / Null Result ReportMedicine
Bedia Cadelo, García Feijoo, Zamorano-Fernandez et al. · 2026 · BMJ case reports
A boy in his early teens presented with transient visual disturbances and headache. Brain imaging revealed bilateral occipital infarctions, while vascular studies demonstrated bilateral V3 vertebral artery wall abnormalities with…
View details →Negative / Null Result ReportMedicine
Dong, Patel, Wang et al. · 2026 · Environment international
Phthalates are pervasive endocrine-disrupting chemicals widely used in consumer products. The wide use of many phthalates results in chronic human exposure to complex mixtures rather than single compounds. Despite extensive studies on…
View details →Replication FailureMedicine
Moses K, Kamaraj, Konda Ramachary Subramanian · 2026 · Drug delivery
Ustekinumab is approved for treating moderate to severe plaque psoriasis, psoriatic arthritis, Crohn's disease, and ulcerative colitis. The Bmab 1200 autoinjector is a simple, two-step device for subcutaneous ustekinumab biosimilar…
View details →Failed Experiment ReportMedicine
Ellis, Perry, Tabbara et al. · 2026 · Journal of vascular surgery cases and innovative techniques
Renovascular hypertension can be clinically challenging to diagnose. The most common etiology remains atherosclerotic disease. When medical management fails, renal artery revascularization is considered. Since the advent of endovascular…
View details →Negative / Null Result ReportMedicine
Malzahn, Höft Budde, Kneißl et al. · 2026 · Innere Medizin (Heidelberg, Germany)
The German healthcare system, despite its high performance, fails to achieve the goal of needs-based service provision. Supply-induced demand, regional disparities and misaligned financial incentives lead to overuse, underuse and misuse of…
View details →Negative / Null Result ReportMedicine
Shigemoto, Kim · 2026 · Psychology, health & medicine
Chronic pain among people of color is influenced by biological, structural, and social forces. While network models have been applied to chronic pain symptoms, research on resource disparities often isolates factors such as income, failing…
View details →Negative / Null Result ReportMedicine
Thiede, Haris, Damjanović et al. · 2026 · Journal of mass spectrometry : JMS
In conventional native mass spectrometry (MS), one faces severe limitations when challenged with heterogeneous, high-mass samples, commonly failing to resolve clear peak distributions, and thus mass determination. Charge detection MS…
View details →Failed Experiment ReportMedicine
Connacher, Hu, Roden et al. · 2026 · RNA biology
Brain tumor (Brat) is a Drosophila TRIM-NHL protein required for embryogenesis and neural stem cell differentiation. Although structural and biochemical studies established that the Brat NHL domain specifically binds RNA, the in vivo…
View details →Negative / Null Result ReportMedicine
Taylor, Roberts, Rayner · 2026 · Viruses
Chikungunya virus (CHIKV) is an alphavirus that infects dermal fibroblasts as a primary target cell during natural mosquito-borne transmission. While primary human dermal fibroblasts (hDFs) have been implicated as a key source of type I…
View details →Negative / Null Result ReportMedicine
Canton, Ceballos, Canton et al. · 2026 · Pharmaceutics
Background/Objectives: Combination of antiparasitic drugs with different mechanisms of action has been suggested as an effective strategy to delay the development of parasite resistance. Considering the need to understand the…
View details →Negative / Null Result ReportMedicine
Perez Arteaga, Yeh · 2026 · Nutrients
Surgical trauma triggers a complex metabolic and inflammatory response that can profoundly affect patient recovery and clinical outcomes. The magnitude of this stress response correlates with surgical complexity, patient comorbidities, and…
View details →Negative / Null Result ReportMedicine
Tan, Lye, Patel et al. · 2026 · International journal of molecular sciences
Heart failure is a leading cause of global morbidity and mortality, often developing as a consequence of acute myocardial infarction. Current management focuses on timely reperfusion via percutaneous coronary intervention. Yet, this…
View details →Negative / Null Result ReportMedicine
Ullah, Li, Aljasir et al. · 2026 · Life (Basel, Switzerland)
Background : Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor with limited treatment options. Tumors harboring the BRAF V600E mutation exhibit aggressive behavior and present therapeutic challenges. Although…
View details →Negative / Null Result ReportMedicine
Kuchana, Repalle, Alahari et al. · 2026 · Cancers
Artificial intelligence (AI) is reshaping oncology at every stage of the cancer care pathway, from population-level screening through molecular diagnosis, treatment planning, and post-treatment surveillance. Despite an exponential growth…
View details →Negative / Null Result ReportMedicine
Jiang, Qi, Ma et al. · 2026 · Veterinary research
Feline calicivirus (FCV) evolves rapidly under immune pressure, yet the genetic basis of antigenic escape remains poorly understood, particularly when sequence divergence is limited. We isolated 13 FCV strains from cats in Jilin Province,…
View details →Negative / Null Result ReportMedicine
Liu, Su, Gong et al. · 2026 · BMC infectious diseases
Chlamydia abortus primarily causes abortion and stillbirth in animals and is associated with pregnancy-related complications in humans. However, it is an extremely rare cause of pneumonia in humans. While Chlamydia psittaci is a…
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