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Browse the failure-mode index

21,300 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Comparing Clinical and Radiological Outcomes for a Three-Dimensional Printed Highly-Porous Cup and a Hydroxyapatite-Coated Non-Highly-Porous Cup in Total Hip Arthroplasty Using Propensity Score Matching.

Okazaki T, Imagama T, Matsuki Y et al. · 2026 · The Journal of arthroplasty

Background The use of highly-porous acetabular components in total hip arthroplasty (THA) has gained popularity. To elucidate the clinical and radiological outcomes of three-dimensional (3D)-printing highly porous cups, we compared…

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Negative / Null Result ReportMedicine

Hamstring-to-quadriceps ratio across menstrual cycle phases in physically active women: a repeated-measures study.

Heinrich C, Hofstaetter H, Puschkasch-Möck S et al. · 2026 · European journal of applied physiology

Objective To evaluate conventional hamstring-to-quadriceps ratio across the menstrual cycle in distinct angular velocities in an eumenorrheic, physically active population. Design Repeated measures within-subjects design. Methods…

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Negative / Null Result ReportMedicine

Medium Cut-Off Versus High-Flux Dialyzers and Changes in Beck Depression Inventory Scores in Maintenance Hemodialysis: An Exploratory Observational Study.

Avsar FN, Erinc O, Sahutoglu T · 2026 · Hemodialysis international. International Symposium on Home Hemodialysis

Introduction Depression is prevalent in maintenance hemodialysis patients and is influenced by the interplay of physical and mental health. Rather than a direct antidepressant effect of dialyzer membrane type, improved clearance of middle…

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Negative / Null Result ReportMedicine

Acute cholecystitis in the robotic era: comparative safety and feasibility of robotic and laparoscopic cholecystectomy in an acute care surgery service.

Pontecorvo AA, Cornejo J, Tsenteradze T et al. · 2026 · Journal of robotic surgery

This study aimed to evaluate and compare perioperative outcomes of robotic versus laparoscopic cholecystectomy in patients with acute cholecystitis within an Acute Care Surgery setting. A retrospective cohort study was conducted including…

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Negative / Null Result ReportMedicine

Interaction model of client health behavior-based nursing intervention improves outcomes in patients with pressure injury: A quasi-experimental study.

Guan X, Li X, Yue M et al. · 2026 · Scientific reports

Pressure injury (PI) prevention requires sustained nursing behaviors from patients, caregivers, and nurses. This single-center quasi-experimental, non-randomized, non-equivalent control group study enrolled 60 inpatients with PI or high PI…

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Negative / Null Result ReportMedicine

Child maltreatment recognition and reporting attitudes among pediatric nurses and physicians in Türkiye: A cross-sectional comparative study.

Çarikçi F, Girgin BA, Harmanci NF et al. · 2026 · Child abuse & neglect

Aim To examine and compare the proficiency of pediatric physicians and nurses in recognizing the signs of and risk factors for child maltreatment, as well as to determine the relationship between this proficiency and their reporting…

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Negative / Null Result ReportMedicine

Safety and Efficacy of Oral Tacrolimus Induction Therapy in Elderly Patients with Ulcerative Colitis: A Subanalysis of a Large Multicenter Retrospective Cohort Study.

Inokuchi T, Hiraoka S, Oshima N et al. · 2026 · Gerontology

Introduction We previously reported the findings of a multicenter retrospective cohort study investigating the efficacy of oral tacrolimus induction therapy in patients with ulcerative colitis (UC). In this subanalysis, we specifically…

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Negative / Null Result ReportMedicine

Reduced Left Atrial Reservoir Strain Is Associated with Histopathologically Confirmed Atrial Natriuretic Peptide-Amyloid Deposition.

Nishino S, Asada Y, Nishino C et al. · 2026 · Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography

Background Isolated atrial amyloidosis is characterized by atrial natriuretic peptide- (ANP-) amyloid deposition confined to the atria and has been primarily linked to atrial fibrillation. However, its relationship with atrial mechanical…

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Negative / Null Result ReportOpen accessMedicine

Enamel Microhardness of Resin-Infiltrated White Spot Lesions After Bleaching With and Without ACP: An In Vitro Study.

Hegde P, Acharya SR, Mayya A et al. · 2026 · International journal of dentistry

Background White spot lesions (WSLs) represent the earliest clinical manifestations of enamel demineralization. Resin infiltration (RI) is a minimally invasive method used to mask WSLs for esthetic improvement; however, infiltrated enamel…

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Negative / Null Result ReportMedicine

Comparative Evaluation of Mealworm (Tenebrio molitor) Larvae as an Alternative Diet for the Mass Rearing of Nesidiocoris tenuis.

Lee J, Hwang HS, Li Y et al. · 2026 · Archives of insect biochemistry and physiology

Nesidiocoris tenuis is an important natural enemy widely used for the biological control of small pests in vegetable crop systems. Its successful implementation in commercial programs depends on reliable and cost-effective mass rearing,…

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Negative / Null Result ReportOpen accessMedicine

Early Immune Alterations in Adult Patients with Trauma According to Injury Severity: Cell-Death Patterns and Inflammatory Mediator Profiles.

Park SJ, Kim JY, Yun S et al. · 2026 · Journal of clinical medicine

Background/Objectives : Trauma triggers complex early immune responses. However, the relationship among trauma severity, changes in immune cell survival, and circulating inflammatory mediators remains unclear. This study compared early…

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Negative / Null Result ReportMedicine

Longitudinal Changes in Health Utility Scores During the Perioperative Period Among Patients With Oral Cancer: An Analysis of the Effect of Older Age and Social Background.

Sasaki M, Aoki T, Uchibori M et al. · 2026 · Oral diseases

Objective Many countries have implemented health technology assessment of their public medical insurance programs owing to rising social security costs from ageing populations and expensive emerging medical technologies. Clarifying factors…

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Negative / Null Result ReportMedicine

The effect of two types of pyramidal and reverse pyramidal loading on spine and pelvis coordination variability during deadlift.

Sajedi Nia M, Khaleghi Tazji M, Abbasi A · 2026 · BMC musculoskeletal disorders

Purpose To investigate the effects of pyramidal and reverse pyramidal loading on spine and pelvis coordination patterns and their variability during deadlift. Methods Twelve trained male powerlifters performed deadlifts under two loading…

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Negative / Null Result ReportOpen accessMedicine

Dimensional accuracy of dental impression materials evaluated using a standardized CAD based method across materials tray types and techniques.

Wassermann C, Rosenberger N, Gerhardt M et al. · 2026 · Scientific reports

In this in vitro study, a CAD-based test workflow was established to evaluate the dimensional accuracy of conventional dental impression materials under standardized laboratory conditions. Ninety double-mix impressions were made from a…

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Negative / Null Result ReportMedicine

Comparison of mechanical complications between metal-ceramic and monolithic zirconia implant-supported prostheses: A retrospective split-mouth study.

Park JO, Park YB, Yoon JH et al. · 2026 · The Journal of prosthetic dentistry

Statement of problem Comparative studies assessing monolithic zirconia and metal-ceramic for implant-supported fixed prostheses remain limited. Purpose This retrospective study aimed to compare the survival and success of metal-ceramic and…

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Negative / Null Result ReportMedicine

Age-stratified clinical outcomes and adverse events in patients with metastatic castration-sensitive prostate cancer receiving triplet therapy with darolutamide, androgen deprivation therapy, and docetaxel.

Uchimoto T, Hirosuna K, Niigawa H et al. · 2026 · Japanese journal of clinical oncology

Background Triplet therapy with darolutamide, androgen deprivation therapy, and docetaxel (DOC) has emerged as an intensified treatment option for metastatic castration-sensitive prostate cancer (mCSPC). This study evaluated real-world…

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Negative / Null Result ReportMedicine

Effect of postural conditions on pinch strength and manual dexterity in young adults: a cross-sectional study.

Büğüşan Oruç S, Akdağ Mirzaoğlu N, Yakut Y · 2026 · International journal of occupational safety and ergonomics : JOSE

Objectives . This study aimed to investigate pinch strength and manual dexterity in different postures among young adults. Methods . A total of 200 individuals aged 18-45 years participated. Key, tip and palmar pinch strengths were…

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