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Browse the failure-mode index

21,300 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Exploratory Study of Radiation Exposure between Image Intensifier-Equipped C-Arm and a Flat Panel Detector During Volar Plate Fixation of the Distal Radius.

Honda Y, Kaida E, Miyazaki Y et al. · 2026 · The journal of hand surgery Asian-Pacific volume

Background: To compare the amount of radiation exposure received by the surgeon during volar locking plate fixation for distal radius fractures using an image intensifier (II) and a flat panel detector (FPD). Methods: We included 40…

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Negative / Null Result ReportOpen accessMedicine

Evaluation of the effects of different irrigation activation techniques on the surface roughness of dentin and blood clot in regenerative endodontic models.

Bulak Yeliz S, Uğur Aydın Z · 2026 · Lasers in medical science

Regenerative endodontic treatment (RET) is a biologically based approach aiming to restore the pulp-dentin complex in immature permanent teeth with necrotic pulps. In this procedure, a blood clot is induced within the canal to serve as a…

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Negative / Null Result ReportOpen accessMedicine

Clinical Status and Salivary aMMP-8 Evaluation of 0.12% Chlorhexidine Versus MicroRepair<sup>®</sup> ABX Mouthwash in the Non-Surgical Management of Plaque-Induced Gingivitis: A Randomized Controlled Trial.

Scribante A, Pascadopoli M, Pellegrini M et al. · 2026 · Dentistry journal

Objectives : To compare the adjunctive efficacy of a MicroRepair ® mouthwash containing an antibacterial complex (ABX), composed of cetylpyridinium chloride, magnolol, and honokiol, with 0.12% chlorhexidine (CHX) in the management of…

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Negative / Null Result ReportOpen accessMedicine

Safety of flexible bronchoscopy in elderly patients.

Spiegel S, Hübner RH, Schürmann D et al. · 2026 · BMC pulmonary medicine

Background Flexible bronchoscopy is an indispensable tool in respiratory medicine. In the context of an aging society and increasing life expectancy, the number of elderly, often multimorbid patients is growing. This raises important…

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Negative / Null Result ReportOpen accessMedicine

Effect of conventional warm-up versus stretching warm-up on physical performance in children soccer players: a randomized crossover trial.

Hernandez-Martínez J, Cid-Calfucura I, Perez-Carcamo J et al. · 2026 · Frontiers in physiology

Introduction To evaluate the effects of the conventional warm-up (CC) compared to warm-ups that included static (SSC), dynamic (DSC), or ballistic (BSC) stretching on jump performance (CMJ, SJ, DJ), curve sprint speed, agility (ICODT), and…

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Negative / Null Result ReportOpen accessMedicine

Assessment of pain and post-injection induration in children: A comparative study of cold application, manual pressure, and shot blocker techniques.

Sasireka V, Bhuvaneswari G, Babu S · 2026 · Journal of education and health promotion

Background Intramuscular (IM) injections are widely used in pediatric care but often cause pain and distress. Effective management is essential to improve children's healthcare experiences. Non-pharmacological methods, including Cold…

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Negative / Null Result ReportOpen accessMedicine

Critical care ultrasound evaluation of snuffbox artery vascular tension: a prospective observational study between healthy volunteers and intensive care unit patients.

Qin Y, Zhu Y, Dai X et al. · 2026 · Frontiers in medicine

Background Systemic vascular resistance is conventionally assessed using invasive methods; the snuffbox artery resistance index (RI) is a superior non-invasive predictor of lactate clearance in septic shock patients to the perfusion index.…

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Negative / Null Result ReportMedicine

Comparable survival over an extended follow-up after on-pump versus off-pump coronary artery bypass grafting: a propensity score-matched cohort.

Pikkujämsä A, Rinne P, Wistbacka JO et al. · 2026 · BMC cardiovascular disorders

Background Long-term survival following off-pump coronary artery bypass grafting (OPCAB) compared with conventional on-pump coronary artery bypass grafting (ONCAB) remains uncertain. Randomised trials and meta-analyses up to 5-10 years…

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Negative / Null Result ReportMedicine

Impact of music intervention on endoscopic retrograde cholangiopancreatography patients' pain, anxiety, and vital signs: a randomized controlled trial.

Çakır E, Ciğerci Y, Yılmaz S · 2026 · Scientific reports

This study aimed to evaluate the effects of a music intervention on anxiety, pain, and vital signs in patients undergoing Endoscopic Retrograde Cholangiopancreatography (ERCP). This randomized controlled trial included 70 patients who…

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Negative / Null Result ReportMedicine

Automated Rigo Classification: An Innovative Artificial Intelligence System.

Schmidt N, Johnson G, Nencka A et al. · 2026 · Studies in health technology and informatics

Although there is variation in clinicians' application of the Rigo classification system (RCS) to adolescent idiopathic scoliosis, no artificial intelligence (AI) models have been developed to standardize the RCS specifically. This study…

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Abandoned HypothesisOpen accessMedicine

Emotion regulation skills training for adolescents and parents in a clinical setting: a randomised controlled trial.

Holmqvist Larsson K, Falkenström F, Andersson G et al. · 2026 · Child and adolescent psychiatry and mental health

Background Emotion dysregulation is a transdiagnostic construct associated with psychiatric symptomatology. Improving strategies to regulate emotions is an important focus in several psychological treatments. In the current study we…

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Abandoned HypothesisOpen accessMedicine

Implantation of a Continuous-Flow Left Ventricular Assist Device During Cardiopulmonary Bypass Is Associated with a Significant and Transient Acute Thromboinflammatory Response.

Gerogianni A, Sørensen G, Hoel TN et al. · 2026 · International journal of molecular sciences

Left ventricular assist device (LVAD) implantation is a life-saving therapy for end-stage heart failure but may compromise immune integrity. Mechanical shear stress and surface-induced innate immune activation can trigger bleeding and…

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Negative / Null Result ReportMedicine

Mid-term clinical outcomes of mobile-bearing UKA: a retrospective study on the influence of patellofemoral joint disease, lower limb alignment, and implant positioning.

Chen M, Zhang C, Fan Z et al. · 2026 · BMC musculoskeletal disorders

Background Unicompartmental knee arthroplasty (UKA) has become an effective treatment for medial compartment osteoarthritis of the knee. However, its use in patients who also have patellofemoral joint osteoarthritis (PFOA) before surgery…

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Negative / Null Result ReportOpen accessMedicine

Deficit irrigation and grafting effects on soil attributes, vegetative growth, yield components, and quality of 'Crimson Seedless' grapevines under a semiarid region.

Salama AM, Al-Obeed RS, Helmy A et al. · 2026 · Frontiers in plant science

This study evaluated the combined effects of grafting and deficit irrigation (DI) on soil attributes, vegetative growth, yield components, fruit quality, and water productivity of 'Crimson Seedless' grapevines under semiarid conditions. It…

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Negative / Null Result ReportMedicine

Comparison of the efficacy of posterior lumbar interbody fusion and transforaminal lumbar interbody fusion in the treatment of double-level lumbar spondylolisthesis combined with spinal stenosis: a retrospective comparative study.

Ma Z, Luan H, Abulimiti K et al. · 2026 · BMC surgery

Objective To compare the clinical and radiographic outcomes of posterior lumbar interbody fusion (PLIF) and transforaminal lumbar interbody fusion (TLIF) in the treatment of double-level lumbar spondylolisthesis combined with spinal…

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Negative / Null Result ReportMedicine

The Effect of Preoperative Tranexamic Acid on Blood Transfusions in Geriatric Hip Fracture Surgery: A Randomized Controlled Trial.

Sullivan M, Perea LL, Bradburn E et al. · 2026 · Journal of orthopaedic trauma

Objectives To evaluate whether preoperative intravenous tranexamic acid (TXA) reduces postoperative blood transfusion rates in geriatric patients undergoing operative treatment for hip fracture. Methods Design Prospective, double-blinded,…

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Negative / Null Result ReportOpen accessMedicine

A comparative study of clinical efficacy, electrophysiological outcomes, and perioperative parameters between endoscopic carpal tunnel release and open carpal tunnel release for carpal tunnel syndrome.

Zhang Z, Liu Y, Yang H et al. · 2026 · Frontiers in cellular neuroscience

Purpose To compare the clinical efficacy of endoscopic (ECTR) and open (OCTR) carpal tunnel release for carpal tunnel syndrome (CTS) and provide evidence-based surgical guidance. Methods A retrospective cohort study was conducted including…

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Negative / Null Result ReportOpen accessMedicine

Comparison of the Bond Strength of Silane-Treated Glass Fiber Posts at Different Solvent Evaporation Times: An In Vitro Study.

Ramos-Ramos V, Dextre-Herrera S, Ramírez-Vargas G et al. · 2026 · Journal of clinical and experimental dentistry

Background Silane is used as a coupling agent on glass fiber posts to enhance chemical interaction at the post-resin cement interface. This in vitro study evaluated the bond strength of silane-treated glass fiber posts at different solvent…

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