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WASTE Journal

Browse the failure-mode index

21,733 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Phytochemical investigation of Phyllanthus emblica (Amla) for therapeutic application in urinary tract infection (UTI) management and development of functional tea.

Ashraf S, Ismail T, Akhtar S et al. · 2026 · Ultrasonics sonochemistry

Phyllanthus emblica L. (amla) is a medicinal fruit, rich in secondary metabolites with reported anti-inflammatory and antimicrobial effects. The current study aimed to assess the impact of drying and extraction techniques on phytochemical…

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Negative / Null Result ReportMedicine

Unveiling glomerulonephritis in the Pacific: a Fijian cohort study.

Krishna J, Khan Z, Chandra Y et al. · 2026 · Journal of nephrology

The epidemiology of kidney diseases is poorly known in several settings, including the Pacific Islands. To contribute to filling this gap, the current study aims to explore the incidence, distribution and patterns of biopsy-proven…

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Negative / Null Result ReportMedicine

Associations of Fasting Glucagon and the Glucagon-Alanine Index With Hepatic Steatosis and Liver Stiffness in Japanese Individuals With Type 2 Diabetes.

Hattori T, Hamaguchi M, Hashimoto Y et al. · 2026 · Diabetes, obesity & metabolism

Background In type 2 diabetes, impaired glucagon action in the liver (hepatic glucagon resistance) may disrupt the liver-α-cell axis. We examined the associations of fasting glucagon and a modified glucagon-alanine index (GAI) with…

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Negative / Null Result ReportMedicine

Comparative morbidity and outcomes for adult spinal deformity corrections spanning C2-pelvis compared to T4-pelvis: a propensity score-matched analysis.

Yahanda AT, Joseph K, Bui TT et al. · 2026 · Spine deformity

Purpose Surgical corrections for adult spinal deformity (ASD) often extend from T4-pelvis. Certain patients may require fusion from C2-pelvis. Comparisons are necessary to guide surgical decision-making, particularly for frailer patients…

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Failed Experiment ReportMedicine

Exploratory Machine Learning-Based Classification of Type 2 Diabetes Using Routine Clinical Parameters: A Single-Center Comparative Study.

Bülbül N, Çiftçi R, Atik İ et al. · 2026 · Healthcare (Basel, Switzerland)

Background/Objectives: Type 2 diabetes mellitus (T2DM) is a prevalent metabolic disorder associated with substantial long-term morbidity and mortality. Routinely collected anthropometric, biochemical, and hematological variables may…

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Negative / Null Result ReportMedicine

Implicit Global-Local Learning in Young People With and Without Autism.

Ziva A, Ziori E, Pothos EM · 2026 · Quarterly journal of experimental psychology (2006)

Implicit (unconscious) learning ostensibly affects cognitive and social skills in both typical and atypical populations, such as those on the autism spectrum. Research into implicit learning in autism has yielded conflicting results,…

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Negative / Null Result ReportMedicine

End-to-end multimodal attention fusion for drug-target interaction prediction with cold-scaffold validation on the Davis kinase benchmark.

Agboola OE, Agboola SS, Shaleye AB et al. · 2026 · Journal of molecular graphics & modelling

Predicting drug-target interactions computationally is a practical strategy for prioritizing candidate compounds in early drug discovery, but the reliability of published models is often limited by small resampled datasets, warm-only…

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Negative / Null Result ReportMedicine

The Diagnostic Value of English Language Sample Measures for Identifying Developmental Language Disorder in Bilingual Children.

Ramos MN, Bedore LM, Peña ED · 2026 · American journal of speech-language pathology

Purpose This study examines the diagnostic accuracy of four measures derived from English narrative language samples for identifying developmental language disorder (DLD) in 5- and 6-year-old Spanish-English bilinguals. Method Ninety-two…

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Abandoned HypothesisMedicine

Hermann J. Muller's research swan song: His long-term radiation dose-rate mutation investigations yielded no research publications, leaving questions of scientific misconduct.

Calabrese EJ · 2026 · Chemico-biological interactions

This paper evaluates the final major research effort of Hermann J. Muller, Nobel Laureate, to assess whether radiation displays a dose-rate process for radiation-induced germ cell mutation. Muller tried to extend the dose-rate findings of…

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Abandoned HypothesisOpen accessMedicine

Ugi multicomponent reactions of optically active aldehydes and chiral aminoindanols: diastereoselective synthesis of bisamides relevant to SARS-CoV-2 Mpro inhibitors.

Ghosh AK, Bhattacharjee A, Jayashankar U et al. · 2026 · Organic & biomolecular chemistry

We have investigated diastereoselective Ugi-multicomponent reactions (Ugi-MCR) relevant to bis-amide scaffolds related to SARS-CoV-2 main protease (Mpro) inhibitors. The studies were mainly focussed on development of diastereoselective…

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Methods Dead-End

Comparative Performance of Gaussian Plume and Backward Lagrangian Stochastic Models for Near-Field Methane Emission Estimation Using a Single Controlled Release Experiment

Upreti A, Shonkwiler K, Riddick SN et al. · 2026 · Preprint

Methane (CH4) is a major component of natural gas and a potent greenhouse gas. Increasing atmospheric methane concentrations are attributed to emissive anthropogenic activities by an average of 13 ppb per yr since 2020 and are linked to a…

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Negative / Null Result ReportMedicine

Development of a Prognostic Prediction Model for Clinically Significant Prostate Cancer Based on Lesion Zone and Apparent Diffusion Coefficient Value Quantification.

Ashouri R, Reynolds PS, Rajavel S et al. · 2026 · Urology

Objective To guide biopsy decision making via a predictive model for clinically significant prostate cancer (csPCa) in men with positive imaging (PI-RADS 3-5). We aim to elucidate the influence of zone on the predictive accuracy of PI-RADS…

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Negative / Null Result ReportMedicine

Reassessing the Incidence and Risk Factors of Radiation Pneumonitis in Treatment-Naive EGFR-Mutant NSCLC With Concurrent Third-Generation EGFR-TKI and Thoracic Radiotherapy.

Zheng, Jia, Jing et al. · 2026 · International journal of cancer

This single-center retrospective study evaluated radiation pneumonitis (RP) in 209 treatment-naive EGFR-mutant non-small cell lung cancer (NSCLC) patients receiving first-line third-generation EGFR tyrosine kinase inhibitors (EGFR-TKIs)…

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Null DatasetMedicine

Establishment of an LNA-TaqMan Fluorescent Quantitative PCR Assay for Differential Diagnosis of Virulent and Attenuated Strains of Short Beak and Dwarfism Syndrome Virus.

Lin, Cheng, Chen et al. · 2026 · Avian pathology : journal of the W.V.P.A

Abstract To enable differential detection of virulent and attenuated strains of duck short beak and dwarfism syndrome virus (SBDSV), we developed a fluorescent quantitative PCR (qPCR) assay based on locked nucleic acid (LNA)-TaqMan probes.…

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