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Browse the failure-mode index

21,294 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Pelvic Floor Health Knowledge With Enhanced Education During Pregnancy.

Nicola-Ducey L, Ward L, Holland A et al. · 2026 · Urogynecology (Philadelphia, Pa.)

Importance Prior to delivery, there are postpartum pelvic floor recovery topics to provide education on; however, because of a variety of factors, the majority of these are commonly unaddressed, leaving a patient unknowledgeable and…

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Negative / Null Result ReportMedicine

Enhancing Intercultural Sensitivity Through Collaborative Online International Learning Among Three Countries: A Mixed-Method Study.

Ying Z, Kondo A, De D et al. · 2026 · Journal of transcultural nursing : official journal of the Transcultural Nursing Society

Introduction We evaluated a Collaborative Online International Learning (COIL) programme in enhancing nursing students' intercultural sensitivity and understanding of cultural safety. Methods From April to May 2024, nursing students in…

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Negative / Null Result ReportMedicine

Curcumin nanoparticles combined with narlumosbart regulate wingless-type MMTV integration site (wnt)/β-catenin signaling pathway in osteoblast-like cells.

Zhang H, Zhao Y · 2026 · Pakistan journal of pharmaceutical sciences

Background Narlumosbart is a key agent for modulating bone cell function. Given the potential of curcumin nanoparticles to inhibit cell growth when applied alone. Objectives This study aims to investigate the role of their combination with…

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Negative / Null Result ReportMedicine

Ocular Effects of Topical 1% Cyclopentolate in New Zealand White Rabbits: A Controlled Evaluation of Intraocular Pressure, Pupil Size, and Tear Production.

Arfaee F, Shariati S, Armin A · 2026 · Veterinary ophthalmology

Objective Mydriatic and cycloplegic agents are widely used in veterinary ophthalmology to enable posterior segment examination. This study evaluated the effects of topical 1% cyclopentolate on intraocular pressure (IOP), horizontal pupil…

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Negative / Null Result ReportMedicine

Metagenomic Insights into Gut Microbiota Alterations Following <i>Dendrobium huoshanense</i> Water Extract Intervention in Streptozotocin-Induced Type 1 Diabetic Rats.

Xu HJ, Liu QL, Zhang YF et al. · 2026 · International journal of molecular sciences

Dendrobium huoshanense water extract (DHWE) exhibits hypoglycemic effects in streptozotocin-induced type 1 diabetic (STZ-T1D) rats. However, its regulatory impact on the gut microbiota of T1D rats remains largely unclear. In this study,…

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Negative / Null Result ReportMedicine

The impact of postoperative calcaneocuboid joint articular surface gap and step on long-term outcomes in surgically treated calcaneal fractures: a brief report.

Sayyed-Hosseinian SH, Samadi S, Yazdi P et al. · 2026 · BMC musculoskeletal disorders

Background Calcaneal fractures, the most common tarsal fractures, often result in significant long-term disability and impose substantial healthcare burdens. Surgical intervention aims to restore hindfoot anatomy, but the role of…

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Negative / Null Result ReportMedicine

Effects of Combined Lipid-Based Nutrient Supplements and Malaria Preventive Treatment during Pregnancy on Malaria, Maternal Nutrition, and Birth Outcomes: A Scoping Review.

Parikh P, Zeilani M, Pieret A et al. · 2026 · Nutrition reviews

Malaria and malnutrition adversely affect maternal and neonatal health in Sub-Saharan Africa. While intermittent preventive treatment of malaria in pregnancy (IPTp) is widely used to reduce malaria incidence, the potential additional…

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Negative / Null Result ReportMedicine

Incidence of periprocedural myocardial injury and clinical outcomes after rotational atherectomy vs. intravascular lithotripsy.

Emori H, Shiono Y, Yamanobe H et al. · 2026 · International journal of cardiology

Background Intravascular lithotripsy (IVL) and rotational atherectomy (RA) are established plaque-modifying strategies for heavily calcified coronary lesions. Despite their different mechanisms, the incidence of significant periprocedural…

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Negative / Null Result ReportMedicine

Moderate Dietary <i>Lactobacillus acidophilus</i> Supplementation Enhances Mid-Growth Nutrient Utilization and Shifts Intestinal <i>Lactobacillus</i> and <i>Escherichia coli</i> Counts in Yellow-Feathered Broilers.

Yushanaji B, Zhang X, Tian T et al. · 2026 · Animals : an open access journal from MDPI

This study tested the hypothesis that dietary L. acidophilus would improve nutrient utilization in yellow-feathered broilers mainly through intestinal changes rather than a consistent increase in growth performance. A total of 195…

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Negative / Null Result ReportMedicine

Mitochondrial dysfunction in schizophrenia and its modulation by atypical antipsychotic drugs: A randomized controlled trial.

Shaju A, Mishra BR, Mohapatra D et al. · 2026 · Journal of psychopharmacology (Oxford, England)

BackgroundRecent evidence increasingly links schizophrenia to mitochondrial dysfunction, implicating altered mitochondrial respiratory and metabolic processes in its pathophysiology. Preclinical data suggest that atypical antipsychotics…

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Negative / Null Result ReportOpen accessMedicine

Evaluation of Changes in the Iridocorneal Angle and Anterior Segment Parameters Following Selective Laser Trabeculoplasty in Pseudoexfoliation Glaucoma.

Yıldırım Erdal BD, Bayraktar S · 2026 · Turkish journal of ophthalmology

Objectives To investigate the effects of selective laser trabeculoplasty (SLT) on the iridocorneal angle, anterior chamber, and iris in patients with pseudoexfoliation glaucoma (PEXG) and to evaluate the relationship between these…

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Negative / Null Result ReportMedicine

Effects of exercise mode and intensity on retinal microvascular structure and function in heart failure patients with preserved ejection fraction: a pilot exercise intervention trial.

Streese L, Ritter ET, Schoch R et al. · 2026 · Journal of vascular research

Purpose We aimed to investigate the effect of different exercise modes on retinal microvascular endothelial function in patients with HF with preserved ejection fraction (HFpEF). Methods Twenty-eight patients were randomly allocated to…

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