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WASTE Journal

Browse the failure-mode index

21,290 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Psychobehavioral profiles of eating risk: schema-emotion regulation patterns differ in central adiposity with genotype (FTO rs9939609) as external validator-a pilot study.

Obara-Gołębiowska M · 2026 · Eating and weight disorders : EWD

Purpose To identify person-centered psychological profiles of eating-related risk based on early maladaptive schemas (EMS), emotion regulation difficulties, and eating behaviors, and to examine their external validation using…

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Negative / Null Result ReportOpen accessMedicine

Effect of a Pragmatic eHealth Behavioral Gestational Weight Gain Intervention on Household Chaos in Pregnant People of Lower Socioeconomic Status: Randomized Controlled Trial.

Kracht CL, Falkenhain K, Flanagan EW et al. · 2026 · JMIR mental health

Background Household chaos is an emerging risk factor for childhood obesity development, especially in families with lower socioeconomic status (SES). It is unclear if changes in household chaos, especially in pregnancy, may mediate the…

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Negative / Null Result ReportOpen accessMedicine

Fragile Mentalizing: Lack of Behavioral and Neural Markers of Social Cognition in an Established Social Perspective Taking Task when Combined with Stress Induction.

Cheema S, Augustin C, Göttlich M et al. · 2024 · eNeuro

The growing field of social neuroscience is reliant on the development of robust, ecologically valid paradigms for simulating social interaction and measuring social cognition in highly controlled laboratory settings. Perspective taking is…

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Negative / Null Result ReportOpen accessMedicine

Mirror exposure in adolescents with anorexia nervosa: a feasibility study on body image disturbance and attentional bias.

Pelzer M, Werthmann J, Svaldi J et al. · 2026 · Eating and weight disorders : EWD

Purpose Body image disturbances (BID) are central to anorexia nervosa (AN), influencing its development, maintenance and relapse. While mirror exposure (ME) has been shown to reduce BID in adults, research in adolescents is limited. This…

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Failed Experiment ReportOpen accessMedicine

Inhibition of p38α MAPK increases short-term astrocyte reactivity: the exploratory VIP trial in early Alzheimer's disease.

Gouilly D, Da-Costa A, Vrillon A et al. · 2025 · Journal of neuroinflammation

BACKGROUND: Neuro-inflammation is an early mechanistic target in Alzheimer’s disease (AD). However, the effect of anti-inflammatory drugs on biomarkers of neuro-inflammation has yet to be described. Biomarkers of neuro-inflammation showed…

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Negative / Null Result ReportOpen accessMedicine

A randomized digital behavioral intervention for prenatal and postpartum weight outcomes in women with overweight or obesity: the GROWell trial.

Simmons LA, Phipps JE, Castro-Alvarez S et al. · 2026 · BMC pregnancy and childbirth

Background Rising rates of overweight and obesity globally have led to an increasing number of women who enter pregnancy with excess weight, posing significant health risks to mothers and infants. Mobile health interventions, such as…

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Negative / Null Result ReportMedicine

Effect of genistein and coenzyme Q10 in oxidative damage and mitochondrial membrane potential in an attenuated type II mucopolysaccharidosis cellular model.

Delgado CA, Poletto E, Vera LNP et al. · 2024 · Cell biochemistry and function

Mucopolysaccharidosis type II (MPS II) is an inborn error of the metabolism resulting from several possible mutations in the gene coding for iduronate-2-sulfatase (IDS), which leads to a great clinical heterogeneity presented by these…

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Negative / Null Result ReportOpen accessMedicine

Plasma von Willebrand Factor and ADAMTS13 Interact With <i>APOE</i>-ε4 in Predicting Longitudinal Brain Atrophy and Cognitive Decline Over a 9-Year Follow-Up.

Adegboye HA, Sun Y, Zhang P et al. · 2026 · Journal of the American Heart Association

Background Von Willebrand factor (VWF) and ADAMTS13 (a disintegrin and metalloproteinase with thrombospondin type 1 motif, 13) are linked to dementia risk, and limited evidence suggests apolipoprotein E ( APOE )-ε4 alters VWF release. This…

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Negative / Null Result ReportMedicine

A Field of Her Own: Property Rights and Women's Agency in Myanmar.

Fertig A, Hartman A, Iyer L et al. · 2026 · The journal of politics

Can financial incentives lead households to register land in women's names, thereby providing them with formal property rights? Can formal property ownership improve women's economic outcomes and change decision-making dynamics within the…

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Negative / Null Result ReportOpen accessMedicine

No Association Between Hypnotizability and Basal Ganglia Morphometry.

Picerni E, Piras F, Laricchiuta D et al. · 2026 · Brain sciences

Background: Hypnotizability is a psychophysiological trait measured by standardized scales whose scores indicate the proneness to modify perception, memory, and behavior according to specific suggestions, and to experience the hypnotic…

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Negative / Null Result ReportOpen accessMedicine

How robust are egocentric and altercentric interference effects in social cognition? a test with explicit and implicit versions of a continuous false belief task.

Haskaraca FN, Proft M, Liszkowski U et al. · 2023 · Frontiers in psychology

It has been long assumed that meta-representational theory of mind (ToM) -our ability to ascribe mental states to ourselves and other people- emerges around age four as indicated in performance on explicit verbal false belief tasks. In…

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Negative / Null Result ReportOpen accessMedicine

Administration of ketogenic intervention as a potential treatment during post-traumatic brain injury recovery: a scoping review.

Quddus DY, Aydin S, Waheed AA et al. · 2026 · Frontiers in nutrition

Background Traumatic brain injury (TBI) affects 69 million individuals annually and represents a major global health burden. Ketogenic interventions have emerged as a potential therapy to address deficits following TBI. This scoping review…

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Negative / Null Result ReportMedicine

Effects of the Visual Fidelity of Virtual Environments on Presence, Context-dependent Forgetting, and Source-monitoring Error.

Mizuho T, Narumi T, Kuzuoka H · 2023 · IEEE transactions on visualization and computer graphics

Advances in virtual reality technology have enabled the creation of virtual environments (VEs) with significantly high visual fidelity when compared to real environments (REs). In this study, we use a high-fidelity VE to examine two…

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Negative / Null Result ReportMedicine

Socio-emotional well-being is associated with cognitive function and informant-rated cognitive decline: Results from the Harmonized Cognitive Assessment Protocol in Europe.

Luchetti M, Terracciano A, Karakose S et al. · 2026 · Journal of the International Neuropsychological Society : JINS

Objective This study examines how multiple dimensions of socio-emotional well-being relate to cognitive functioning in older adults, and whether the associations vary by cognitive status, depression, and socio-demographic factors. Methods…

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Negative / Null Result ReportOpen accessMedicine

No immediate attentional bias towards or choice bias for male secondary sexual characteristics in Bornean orang-utans (Pongo pygmaeus).

Roth TS, Samara I, Perea-Garcia JO et al. · 2024 · Scientific reports

Primate faces provide information about a range of variant and invariant traits, including some that are relevant for mate choice. For example, faces of males may convey information about their health or genetic quality through symmetry or…

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Negative / Null Result ReportOpen accessMedicine

Effects of one avocado a day for six months on cognitive performance in overweight adults: A randomized controlled trial.

Lee GJ, Morrell HER, Adams M et al. · 2026 · The journal of nutrition, health & aging

Background With the rising incidence of neurodegenerative diseases and aging of the global population, it is important to investigate foods that may preserve cognitive function with advancing years. Avocados are rich in fiber, carotenoids,…

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