21,733 real negative results, null findings, and replication failures. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Kotenko O, Kozlovskaya N, Emirova K et al. · 2026 · Nephron
Background The objective of a multicentre, prospective, observational study of an eculizumab biosimilar (Elizaria®) was to analyse the efficacy and safety of long-term complement inhibitor therapy in patients with atypical haemolytic…
View details →Tao J, Cheng D, Wang N · 2026 · Preprint
Abstract Background Fluid retention and the obesity paradox often mask true muscle wasting in patients with proteinuric chronic kidney disease (CKD), and conventional quantity-based metrics such as body mass index or cross-sectional tissue…
View details →Joswig H, Oreizi-Esfahani S, Medack S et al. · 2026 · World neurosurgery
Background Parkinson's disease (PD) is a neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra, resulting in motor and nonmotor symptoms including diminished sleep quality and altered dream…
View details →Raza GS, Jokelainen J, Stenbäck V et al. · 2026 · PloS one
Physical activity (PA) has numerous positive health effects, including improvements in cognitive function. PA stimulates the release of glycosylphosphatidylinositol-specific phospholipase D1 (GPLD1) from the liver, resulting in hippocampal…
View details →Esen Öksüzoğlu M, Kabukçu HO · 2026 · BMC psychiatry
Background Sleep terror (ST) is a common NREM parasomnia in early childhood and may be associated with broader emotional and behavioral dysregulation. However, its links with psychopathological symptoms and nutritional biomarkers remain…
View details →Agarwal P, Thapa M, Karki P · 2026 · Preprint
Abstract Background Increase in IOP after Vitreoretinal surgery is uncommon but sight threatening complication. This study aims to determine the incidence and risk factors of intraocular pressure (IOP) elevation following vitreoretinal…
View details →Tcherner S, Durom E, Peters J et al. · 2026 · COPD
In patients with moderate-to-severe COPD, airway mucus-occlusions correlate with airflow limitation, exacerbation and mortality-risk. However, the clinical relevance of mucus-plugs in milder COPD is not well-understood. We evaluated…
View details →Huang F, Chen K · 2026 · Human factors
ObjectiveThis study investigated how affective characteristics of interruptions (valence and arousal) influence task resumptions and post-interruption performance in younger and middle-aged/older adults under different task…
View details →Sevahil D · 2026 · Preprint
The aim of this study was to examine the causal pathways from prosocial behavior to well-being in different grades of primary school children. We assessed for whether family support andpeer acceptance mediate this relationship, along to…
View details →Steen AV, Simmering JA, Perik M et al. · 2026 · BJOG : an international journal of obstetrics and gynaecology
Objective To determine the anatomical effect of pessaries in the upright position in women with pelvic organ prolapse (POP). Design Prospective observational cohort study. Setting Outpatient clinic of our gynaecology department. Population…
View details →Rawat R, Abrahamson CW, Rogers K et al. · 2026 · The Laryngoscope
Objectives To evaluate the effects of swallowing therapy and cricopharyngeus (CP) muscle surgery on upper esophageal sphincter (UES) opening, oral intake, and airway protection in patients with absent UES opening following neurological…
View details →Ponissery Saidu S, Kross A, Dibattista M et al. · 2026 · The Journal of general physiology
Odorants in the inhaled air bind to odorant receptors embedded in cilia of olfactory receptor neurons, triggering the opening of the two ciliary olfactory transduction channels; first, a cationic heterotetrameric cAMP-gated channel,…
View details →Śliwińska A, Świtaj K, Durma AD · 2026 · Nuclear medicine review. Central & Eastern Europe
Background Neuroblastoma (NB) is the most common extracranial solid tumor in children. Metaiodobenzylguanidine (MIBG) selectively accumulates in adrenergic tissue, enabling its use for diagnostic imaging of NB. The implementation of new…
View details →Lehman A, Layton P, Mishkulin S et al. · 2026 · Sexually transmitted diseases
Doxycycline postexposure prophylaxis (doxyPEP) may affect RPR titers. We describe syphilis diagnosis following doxyPEP roll-out. Syphilis diagnoses decreased (3.4%-1.5%) among persons prescribed doxyPEP. Diagnosis without laboratory…
View details →Fenwick A, Glasheen BM, Cammarato A et al. · 2026 · Biophysical reports
Drosophila models have proven invaluable for studying skeletal and cardiac muscle diseases. While permeabilized indirect flight muscle (IFM) and jump muscle fibers from Drosophila yield insightful mechanical data, these preparations cannot…
View details →Graham RR, Salgado BE, Guerrero E et al. · 2026 · European journal of applied physiology
Purpose This pilot study examined whether collagen supplementation, via gelatin, influences indices of skeletal muscle recovery following strenuous exercise. Methods Using a double-blind, randomized, placebo-controlled design,…
View details →Costa D, Guerra A, Birreci D et al. · 2026 · Movement disorders : official journal of the Movement Disorder Society
Background Cervical dystonia (CD) is a movement disorder with a complex pathophysiology, including cerebellar abnormalities. Transcranial alternating current stimulation (tACS), a noninvasive neuromodulation technique capable of entraining…
View details →Giotakis AI, Steinbichler TB, Heppt H et al. · 2026 · The Journal of craniofacial surgery
The exact nasal changes caused by several types of maxillofacial surgery are not yet thoroughly understood. The aim of the present study was to determine the exact nasal airway changes caused by maxillary advancement and impaction. In a…
View details →Hostrup M, Jessen S, Tischer SG et al. · 2026 · Scandinavian journal of medicine & science in sports
Misuse of beta 2 -agonists to promote leanness is increasingly reported among young men undertaking resistance training. However, preclinical models demonstrate adverse cardiac remodeling with high-dose beta 2 -agonist. We investigated…
View details →Rostron ZPJ, Feller JA, McClelland JA et al. · 2026 · Physical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine
Objectives To determine the change in modified star excursion balance test scores in patients between 6 and 12 months following anterior cruciate ligament (ACL) reconstruction and the change in the proportion of patients who met…
View details →Hart HF, Patterson BE, Atkinson HF et al. · 2026 · Journal of sport rehabilitation
Context Weakness of the quadriceps and hamstrings often persists following rehabilitation after anterior cruciate ligament reconstruction (ACLR). Yet, recovery of the gastrocnemius muscle following ACLR remains unclear. Thus, we aimed to…
View details →Takeyama A, Imamura Y, Ichikawa Y et al. · 2026 · Retina (Philadelphia, Pa.)
Purpose To investigate long-term outcome of retinal displacement for 1 year after idiopathic macular hole (MH) surgery with internal limiting membrane (ILM) peeling and evaluate its association with basal MH size. Methods This…
View details →Berk AZ, Balaban O, Eman A et al. · 2026 · BMC anesthesiology
BACKGROUND/OBJECTIVE: Ultrasound-guided subclavian vein (SCV) catheterization offers an alternative approach to the classical jugular vein catheterization for central venous catheter placement. The objective of this study was to evaluate…
View details →Lee CH, Kim KH, Choi YJ et al. · 2026 · Scientific reports
This study investigates the effect of epiretinal membrane (ERM) removal in the combined hamartomas of the retina and retinal pigment epithelium (CHRRPE) patients. In this retrospective, comparative case series, 15 CHRRPE patients were…
View details →Leshno A, Levanon E, Singer R et al. · 2026 · Ophthalmology. Glaucoma
Purpose To evaluate whether the administration of topical steroids is beneficial after elective laser peripheral iridotomy (LPI). Design A prospective, randomized, double-masked, placebo-controlled clinical trial. Participants Twenty-eight…
View details →Cagnacci A, Xholli A, Gabbi L et al. · 2026 · The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception
Objective We investigated the metabolic profile induced by contraceptives containing body-identical oestrogens. Methods A literature search was made for articles on contraceptives with oestradiol/nomegestrol acetate (E2/NOMAc), oestradiol…
View details →Cassís-Nosthas ML, Vorácková FV, Dzib FT et al. · 2026 · Journal of visualized experiments : JoVE
Although the gut microbiota is generally stable, it can be influenced by antibiotic treatment. Rifaximin, which is used to treat gastrointestinal disorders, is frequently administered with probiotics to reduce the risk of dysbiosis.…
View details →Madsen SS, Asghar MS, Lindberg U et al. · 2026 · Journal of applied physiology (Bethesda, Md. : 1985)
Although general anaesthesia is a very common medical procedure, knowledge of how the brain physiologically recovers remains limited. In this randomized cross-over trial, we investigated brain physiology during recovery from general…
View details →Usai DS, Kudryavtseva O, Thomsen MB · 2026 · Journal of cardiovascular pharmacology
Abstract Human arterial blood pressure follows a circadian rhythm, where pressure is highest during the day and lowest during the night. Patients with hypertension can have either a preserved rhythm or a dampened rhythm with a lower…
View details →Rodrigues Santos LE, Elsangedy HM, Acevedo EO et al. · 2026 · Psychological reports
This study investigated the potential of Binaural Beats (BB) stimulations at Beta (20 Hz) and Gamma (40 Hz) frequencies to alter interoceptive accuracy (IAcc) and sensibility (ISen) in individuals with depressive symptoms. Fifty-two…
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