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Browse the failure-mode index

21,733 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Determinants of Patient-Reported Experience After Interhospital Transfer Within an Integrated Health System.

Howick V JF, Lugo-Fagundo NS, Umadat G et al. · 2026 · Journal for healthcare quality : official publication of the National Association for Healthcare Quality

Objective To evaluate patient-reported experiences after interhospital transfer (IHT) within an integrated health system and identify communication and coordination domains associated with overall satisfaction. Methods This retrospective…

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Negative / Null Result ReportMedicine

Microfluidic sperm selection versus density gradient centrifugation in ICSI cycles with abnormal semen parameters: a randomized sibling-oocyte study.

Thanapongpibul C, Niransuk P, Sassanarakkit S et al. · 2026 · Scientific reports

Microfluidic sperm selection (MSS) is a centrifugation-free alternative to density gradient centrifugation (DGC) for sperm preparation in intracytoplasmic sperm injection (ICSI). This prospective, randomized sibling-oocyte study included…

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Negative / Null Result ReportMedicine

Association of the mitochondrial regulator PGC-1α with diabetes mellitus and myocardial ischemia-reperfusion injury in coronary artery bypass grafting.

Yildiz A, Yazici S, Yildiz Z · 2026 · BMC cardiovascular disorders

Objectives This study aimed to evaluate whether peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1α) could serve as a marker of myocardial ischemia by examining its association with cross-clamp time, which reflects…

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Negative / Null Result ReportOpen accessMedicine

Low-flow oxygen delivery in patients with disturbed consciousness.

Yamada SM · 2026 · Surgical neurology international

Background When low-flow oxygen (O2) delivery is required, a nasal cannula is commonly used. However, no reports have described arterial blood gas analysis in actual patients receiving O2 simultaneously through a mask and a nasal cannula.…

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Negative / Null Result ReportMedicine

Susceptibility of sorghum to infestation by Oryzaephilus surinamensis (Coleoptera: Silvanidae) and Trogoderma variabile (Coleoptera: Dermestidae): influence of variety and temperature.

Gourgouta M, Athanassiou CG, Arthur FH et al. · 2026 · Journal of economic entomology

This study evaluated the effects of sorghum variety and temperature on the population growth, frass production, kernel damage, and weight loss caused by Oryzaephilus surinamensis (L.) and Trogoderma variabile, Ballion, two common…

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Negative / Null Result Report

Perceptions of end-of-life care quality among bereaved closest contacts of community-dwelling older Australians: a cross-sectional survey of the ASPREE cohort

Keon-Cohen ZM, Tran C, Jones D et al. · 2026 · Preprint

Abstract Background High-quality end-of-life care (EOLC) is a recognised health and human-rights priority, yet Australian evidence largely derives from administrative data and cancer-specific, facility-based samples. Little is known about…

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Negative / Null Result ReportMedicine

Robotic versus laparoscopic rectal resection: impact on primary postoperative ileus and the role of intraoperative fluid balance: a propensity score-matched cohort study.

Urashima T, Yabuno T, Imanishi K et al. · 2026 · Surgical endoscopy

Background Few studies have directly compared the incidence of primary postoperative ileus (primary POI) between robotic surgery (RS) and laparoscopic surgery (LS) for rectal resection. Methods This retrospective cohort study included…

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Negative / Null Result ReportMedicine

Radial Versus Femoral Access for Diagnostic Coronary Angiography: Insights From a Tertiary Academic Center in Johannesburg.

Ntaka KL, Mpanya D, Adamu UG et al. · 2026 · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

Background The radial artery is the preferred access for performing diagnostic coronary angiograms (DCA). However, data on the safety and efficacy of radial compared to femoral access in low- and middle-income countries is limited. Aims…

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Negative / Null Result Report

Challenging the standard: Comparison of outcomes between Laparoscopically Assisted Anorectoplasty (LAARP) and Posterior Sagittal Anorectoplasty (PSARP) in the correction of rectobulbar fistula in Pediatric Patients

Sanchez MAC, Ruiz J, Siffredi J et al. · 2026 · Preprint

Abstract Background: Posterior sagittal anorectoplasty (PSARP) remains the standard surgical approach for rectobulbar fistula in patients with anorectal malformations (ARM). Laparoscopically assisted anorectoplasty (LAARP) has emerged as…

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Negative / Null Result ReportMedicine

Levels of acylated and deacylated ghrelin are elevated in unmedicated patients with major depressive disorder and obesity: a cross-sectional study.

Lis M, Miłuch T, Krupa R et al. · 2026 · Scientific reports

Major depressive disorder (MDD) frequently co-occurs with obesity, suggesting shared neuroendocrine mechanisms. Ghrelin, a hormone involved in appetite regulation, stress response, and reward processing, has been proposed as a biological…

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Negative / Null Result ReportMedicine

Clinical and radiographic outcomes of cannulated cancellous screw osteosynthesis with and without side-plate for nondisplaced femoral neck fractures: a multicenter propensity score-matched study.

Maeda K, Funahashi H, Tokutake K et al. · 2026 · International orthopaedics

Purpose This study aimed to evaluate postoperative outcomes, including clinical results, radiological assessments, and complications, in patients over 50 years old with nondisplaced femoral neck fractures (Garden classification I-II)…

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Negative / Null Result ReportMedicine

Efficacy and Safety of Denosumab versus Zoledronic Acid in the Treatment of Hypercalcemia in Primary Hyperparathyroidism: A Retrospective Comparative Study.

Liu Y, Liu L, Wang J et al. · 2026 · Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists

Objective Nephrotoxicity of bisphosphonates limits their utility in the management of severe hypercalcemia among patients with primary hyperparathyroidism (PHPT) and impaired renal function. It remains unclear whether denosumab is an…

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Negative / Null Result ReportMedicine

Clinical outcomes of a Locator-bilateral segmental bar concept versus a conventional rigid bar concept for maxillary implant-supported overdentures: a retrospective cohort study.

Zheng J, Chen M, Fu J · 2026 · BMC oral health

Background This retrospective cohort study evaluated a Locator-bilateral segmental bar concept (LBSB) for maxillary implant-supported overdentures and compared it with a conventional rigid bar concept (CRB) in terms of implant survival,…

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Negative / Null Result ReportMedicine

Effectiveness of Audiovisual Distraction During Dental Treatment Under Nitrous Oxide/Oxygen Conscious Sedation in Paediatric Patients: A Randomized Crossover Clinical Trial.

Gentile T, Vanacore S, Caputo M et al. · 2026 · Children (Basel, Switzerland)

Background/objectives Dental anxiety represents a major challenge in paediatric dentistry and is a frequent cause of non-cooperative behaviour during dental treatment. Nitrous oxide/oxygen inhalation conscious sedation is widely used to…

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Negative / Null Result ReportMedicine

The trajectories of relative concentrations of antirhodococcal immunoglobulin A differ from those of immunoglobulin G subisotypes in bronchoalveolar lavage fluid but not serum of foals.

Aucoin AA, Zhidkov V, Legere RM et al. · 2026 · American journal of veterinary research

Objective To characterize age-related trajectories of the relative concentrations of anti-virulence-associated protein A (VapA) immunoglobulin (Ig)-G1, IgG3/5, IgG4/7, and IgA in serum and bronchoalveolar lavage fluid (BALF) as indicators…

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Negative / Null Result ReportMedicine

Combined Pain Neuroscience Education and Progressive Muscle Relaxation for Post-Thoracoscopic Pain.

Wang X, Li W, Wang F et al. · 2026 · Pain management nursing : official journal of the American Society of Pain Management Nurses

Purpose The objective of this study was to evaluate whether combining pain neuroscience education (PNE) with progressive muscle relaxation (PMR) could reduce acute pain after thoracoscopic lung resection, alleviate psychological distress,…

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Negative / Null Result ReportMedicine

Comparing Spinal and General Anesthesia for Prone Percutaneous Nephrolithotomy: A Propensity Score-Matched Study.

Chen L, Xu D, Hou L · 2026 · Medical principles and practice : international journal of the Kuwait University, Health Science Centre

Background/objective Prone percutaneous nephrolithotomy (PCNL) is commonly performed under general anesthesia (GA); however, increasing evidence supports the feasibility of PCNL under spinal anesthesia (SA). This study presents our…

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Negative / Null Result ReportMedicine

Development and Preliminary Clinical Evaluation of a Multifunctional Operative Support Arm in Reproductive Laparoscopic Surgery: A Randomized Controlled Study.

Mao W, Lu N · 2026 · Journal of investigative surgery : the official journal of the Academy of Surgical Research

Objective To evaluate short-term clinical outcomes, surgeon-reported fatigue, and staff user experience associated with a multifunctional operative support arm in reproductive laparoscopic surgery. Design Single-center, parallel-group…

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