Negative / Null Result ReportMedicine
Zhou Y, Tse CS · 2025 · The Journal of general psychology
In English, head is associated with rationality and logic, whereas heart is related to feeling and emotionality. In Chinese, these head- and heart-related metaphors also exist. Could these head- and heart-related conceptual metaphors…
View details →Negative / Null Result Report
Noel M, Suttapitugsakul S, Cummings RD et al. · 2024 · Preprint
Protein O-glycosylation is a critical modification in the brain, as genetic variants in the pathway are associated with both common and severe neuropsychiatric phenotypes. However, little is known about the most abundant type of O-glycan…
View details →Failed Experiment Report
Wickenhagen A, Flagg M, Port J et al. · 2024 · Preprint
The emergence of the Omicron lineage represented a major genetic drift in SARS-CoV-2 evolution. This was associated with phenotypic changes including evasion of pre-existing immunity and decreased disease severity. Continuous evolution…
View details →Negative / Null Result ReportMedicine
Stüber AT, Heimer MM, Ta J et al. · 2025 · European journal of radiology
This study investigates the predictive capability of radiomics in determining programmed cell death ligand 1 (PD-L1) expression (>=1%) status in non-small cell lung cancer (NSCLC) patients using a newly collected [18F]FDG PET/CT dataset.…
View details →Negative / Null Result Report
Centorame G, Warrington NM, Hemani G et al. · 2024 · Preprint
Background Breastfeeding is hypothesised to benefit child health and cognitive functioning by providing long-chain polyunsaturated fatty acids (LC-PUFA), which are essential for brain development. In 2007, Caspi et al. found evidence in…
View details →Negative / Null Result Report
Wiesing M, Zimmermann E · 2023 · Preprint
Intentional actions produce a temporal compression between the action and its outcome, known as intentional binding. However, Suzuki et al. (2019) recently showed that temporal compression can be observed even without intentional actions.…
View details →Negative / Null Result Report
Lloyd B, Wurm F, de Kleijn R et al. · 2023 · Preprint
Background Transcutaneous auricular vagus nerve stimulation (taVNS) is a promising brain stimulation method for the treatment of pharmaco-resistant epilepsy and depression. Its clinical efficacy is thought to depend on taVNS-induced…
View details →Negative / Null Result ReportOpen accessMedicine
Ahrens A, Liesefeld HR, Kinner J et al. · 2026 · Psychological research
In everyday life, we often generalize previously learned associations between our actions and their outcomes to novel, but similar situations. The present study aimed to conceptually and directly replicate results reported by Esser et al.…
View details →Negative / Null Result ReportMedicine
Wentura D, Gurbuz E, Paulus A et al. · 2023 · Journal of experimental psychology. Human perception and performance
When asked to judge or react to a facial emotional display of a person, people do not only take the emotion into account, but also other socially important features of the face, such as, for example, ethnicity (Kozlik & Fischer, 2020;…
View details →Negative / Null Result Report
Dede A, Xiao W, Vaci N et al. · 2023 · Preprint
Abstract Neurodevelopmental disorders are difficult to diagnose, requiring expert clinicians and subjective judgements. Consequently, there has been interest in finding quantitative biomarkers for some disorders using resting state…
View details →Negative / Null Result Report
Marshall K, Thothathiri M · 2023 · Preprint
Comprehenders make predictions about the meaning and structure of linguistic information as the utterance unfolds. However, when the actual content does not match the expectation, costly reanalysis processes are required. Previous work has…
View details →Failed Experiment Report
Whyte-Fagundes P, Vance A, Carroll A et al. · 2023 · Preprint
Dravet syndrome (DS) is a severe genetic epilepsy primarily caused by de novo mutations in a voltage-activated sodium channel gene (SCN1A). Patients face life-threatening seizures that are largely resistant to available anti-seizure…
View details →Negative / Null Result ReportMedicine
Lucchi F, Lloyd B, Nieuwenhuis S · 2024 · Psychophysiology
The vagus nerve is thought to be involved in the allostatic regulation of motivation and energy metabolism via gut-brain interactions. A recent study by Neuser and colleagues (2020) provided novel evidence for this process in humans, by…
View details →Negative / Null Result Report
Hermans P, Vandevoorde K, Orban de Xivry J · 2023 · Preprint
In motor adaptation, learning is thought to rely on a combination of several processes. Two of these are implicit learning (incidental updating of the sensory prediction error) and explicit learning (intentional adjustment to reduce target…
View details →Negative / Null Result Report
Jiang S, Jones M, von Bastian C · 2023 · Preprint
Abstract In recent years, non-invasive brain stimulation has been highlighted as a possible intervention to induce cognitive benefits, including on visual working memory (VWM). However, findings are inconsistent, possibly due to…
View details →Negative / Null Result ReportOpen accessMedicine
Yang Z, Pajuste FD, Zguro K et al. · 2025 · Nature genetics
Understanding disease progression is of high biological and clinical interest. Unlike disease susceptibility, whose genetic basis has been abundantly studied, less is known about the genetics of disease progression and its overlap with…
View details →Negative / Null Result ReportMedicine
Horton CB Jr, Adam H, Galinsky AD · 2025 · Personality & social psychology bulletin
Enclothed cognition refers to the systematic influence that clothes can have on the wearer's feelings, thoughts, and behaviors through their symbolic meaning. It has attracted considerable academic and nonacademic interest, with the 2012…
View details →Negative / Null Result ReportOpen accessMedicine
Chen TA, Chuang YT, Pai SC et al. · 2025 · Microorganisms
Ventilator-associated pneumonia (VAP) remains a significant concern in intensive care units (ICUs), contributing to increased morbidity, mortality, and healthcare costs. Probiotics and synbiotics have been explored as potential preventive…
View details →Negative / Null Result ReportMedicine
Alben N, Arthur C · 2024 · Attention, perception & psychophysics
In the present paper, we carry out a replication of a seminal paper by Kahneman, D. & Beatty, J. (1967). Perception & Psychophysics, 2(3),101-105 for using pupillometry as an implicit measure of auditory processing load, specifically,…
View details →Negative / Null Result Report
Dede AJO, Xiao W, Vaci N et al. · 2023 · Preprint
ABSTRACT Mental health conditions are difficult to diagnose, requiring expert clinicians and subjective judgements. There has been interest in finding quantitative biomarkers using resting state electroencephalogram (EEG) data. Here, we…
View details →Negative / Null Result ReportOpen accessMedicine
Aicoboaie S, Pappaianni E, Abdulkadir M et al. · 2025 · Psychological medicine
Background Shared genetic risk has been shown across psychiatric disorders. In particular, anorexia nervosa (AN), obsessive-compulsive disorder (OCD), and schizophrenia (SCZ) show shared genetic risk that matches clinical evidence of…
View details →Negative / Null Result ReportMedicine
Bechtel GN, Kostelnik CJ, Rausch MK · 2025 · Journal of biomedical materials research. Part A
Tissue mimicking materials are designed to represent real tissue in applications such as medical device testing and surgical training. Thanks to progress in 3D-printing technology, tissue mimics can now be easily cast into arbitrary…
View details →Negative / Null Result ReportOpen accessMedicine
Saladini F, Giannini A, Giammarino F et al. · 2026 · Open forum infectious diseases
Background HIV-1 sub-subtype A6 is predominant in Eastern Europe and was associated with increased risk of treatment failure with the long-acting cabotegravir plus rilpivirine regimen. In this study, we aimed to evaluate the in vitro…
View details →Negative / Null Result ReportOpen accessMedicine
Hoth KF, Voorhies K, Wu AC et al. · 2022 · Journal of psychiatry and brain science
Depression is the most common mental illness in the U.S. affecting nearly 40 million adults age 18 years and older. Depression has both genetic and environmental influences. In addition, women are more likely to be affected by depression…
View details →Negative / Null Result Report
Fang J, Cao Y, Ni J · 2023 · Preprint
Background: Intracranial aneurysm (IA) accounts for a substantial source of non-traumatic subarachnoid hemorrhage, with inflammation postulated as a potential factor in its pathogenesis. The present study aims at evaluating the association…
View details →Negative / Null Result ReportOpen accessMedicine
Davis CN, Jinwala Z, Justice AC et al. · 2025 · Alcohol, clinical & experimental research
Background Topiramate reduces alcohol consumption in individuals who drink heavily. Candidate gene studies aimed at identifying genetic variants that predict topiramate's effects on drinking have yielded inconsistent findings. To identify…
View details →Failed Experiment ReportOpen accessMedicine
Bender O, Shemesh OA, Bar DZ · 2026 · Journal of Alzheimer's disease : JAD
The etiology of Alzheimer's disease (AD) remains a subject of intense investigation. While the 2024 Lancet Commission report attributes approximately 45% of global dementia cases to 14 modifiable risk factors, it notably excludes…
View details →Negative / Null Result ReportOpen accessMedicine
Ruuskanen V, Hagen T, Espeseth T et al. · 2024 · Journal of cognition
Over the past few years, several studies have explored the relationship between resting-state baseline pupil size and cognitive abilities, including fluid intelligence, working memory capacity, and attentional control. However, the results…
View details →Negative / Null Result ReportOpen accessMedicine
Baldé AM, Schellenberg EG, Lima CF · 2026 · Psychonomic bulletin & review
Why does musical expertise predict enhanced emotion recognition in speech prosody? Evidence for a causal role of music training is weak, and correlations with musical aptitude could reflect basic auditory abilities rather than musicality…
View details →Negative / Null Result Report
Morriss J, Lee CE, Wood A et al. · 2023 · Preprint
Background and Objectives: Attentional biases to negative information are often observed in emotional disorders such as anxiety and depression. Recently, Fergus et al. (2013) demonstrated that participants scoring high in Intolerance of…
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