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Browse the failure-mode index

21,287 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Effects of reduced metabolizable protein diets supplemented with rumen-protected His under adequate Met and Lys supply on production, nutrient digestibility, N utilization, and manure ammonia emissions in lactating cows.

Park K, Kim J, Hu H et al. · 2026 · Journal of dairy science

Balancing for limiting AA may prevent reduced production when deficient MP is provided. The objective of the study was to determine the effects of rumen-protected (RP) His supplementation at different levels of MP when Lys and Met supplies…

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Negative / Null Result ReportMedicine

Are gaps in the time of submissions and approvals of new drugs between Health Canada and the Food and Drug Administration related to therapeutic value? A cross-sectional study.

Lexchin J · 2026 · Health policy (Amsterdam, Netherlands)

Background Health Canada is proposing to use decisions by foreign regulators in approving new drugs to speed up their marketing. Objectives To investigate the length of gaps in submissions to and approvals by Health Canada compared to the…

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Negative / Null Result ReportMedicine

Do potentially traumatic events experienced by people in one's social circle affect one's own mental health and emotional support? Findings from a prospective population-based study.

van der Velden PG, Contino C, Kempe S et al. · 2026 · Acta psychologica

Background Adults may have individuals in their social circle who were recently exposed to potentially traumatic events (PTEs). The present study aims to examine if these adults are at increased risk for mental health problems and reduced…

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Negative / Null Result ReportMedicine

Optimizing Necrotizing Otitis Externa Management: The Role of PET-CT in Antibiotic Stewardship.

Zammit M, Davies T, Youssef A · 2026 · Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology

Objective To optimize antibiotic regimens in necrotizing otitis externa (NOE) and skull base osteomyelitis (SBO) and evaluate the role of positron emission tomography-computed tomography (PET-CT) in disease monitoring. Study design A…

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Failed Experiment ReportMedicine

Pre-post implementation study of a medication-focused order set for management of acute agitation in a pediatric emergency department.

Mills KP, Kemper M, Hoganson GM et al. · 2026 · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists

Purpose To assess changes in prescribing practice after implementation of a medication-focused order set for acute agitation management in a pediatric emergency department (ED). Methods Patients 5 to 18 years of age who presented to the…

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Failed Experiment ReportMedicine

Field evaluation in the Eastern United States of a biological control Blossom Protect for fire blight suppression efficacy, potential to cause fruit russeting, and compatibility with fungicides.

Zeng Q, Cox K, Jung J et al. · 2026 · Plant disease

Fire blight is a destructive disease of apple and pear, and its severity is intensified under humid conditions. Biological controls are important components of the integrated management of plant diseases; however, field trials in the…

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Negative / Null Result ReportMedicine

Tolerability and effectiveness of definitive chemoradiotherapy in locally advanced lung cancer patients with combined pulmonary fibrosis and emphysema.

Fujimoto K, Kogo M, Kobayashi H et al. · 2026 · Cancer treatment and research communications

Background This study evaluated the efficacy and safety of definitive chemoradiotherapy (CRT) for lung cancer in patients with combined pulmonary fibrosis and emphysema (CPFE), focusing on radiation pneumonitis (RP). Materials and methods…

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Negative / Null Result ReportMedicine

DNAemia Thresholds to Discontinue Antivirals in Preemptive Management for Cytomegalovirus Seropositive Recipients After Kidney Transplantation.

Miehrig AH, Foresto RD, Tedesco-Silva H et al. · 2026 · Transplantation

Background Treatment of cytomegalovirus (CMV) after kidney transplantation aims to achieve cessation of viral replication; however, the use of highly sensitive DNA assays creates uncertainty regarding the optimal DNAemia threshold for…

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Negative / Null Result ReportMedicine

Physiologic, Psychological, Nutritional, and Rest-Activity Observations During 120 Days of Low-Tech Off-Grid Living in the Baja California Desert: A 2-Participant Field Case Study.

Mauvieux B, Montardy Q, Remilly M et al. · 2026 · Wilderness & environmental medicine

Off-grid low-tech living is increasingly proposed for arid environments, yet longitudinal field data documenting health, nutrition, and rest-activity organization under real-world conditions remain scarce. Our objective was to describe…

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Negative / Null Result ReportMedicine

A description of self-selected treatments and self-reported improvement following treatment among post-9/11 veterans experiencing disruptive dizziness following a comprehensive traumatic brain injury evaluation.

Cheever K, Kalvesmaki A, Swan AA et al. · 2026 · Brain injury

Background This study aimed to explore what treatments were sought by post-9/11 Veterans with and without a formal diagnosis related to their long-term dizziness following completion of a Comprehensive Traumatic Brain Injury Evaluation…

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Negative / Null Result Report

Recovery of a WWTP fertilizer added with plant growth promoting bacteria (PGPB). Relationship with antibiotic resistance in the "One Health" environment with an oak species: Quercus ilex

Fernández-Pastrana VM, González-Reguero D, Robas-Mora M et al. · 2026 · Preprint

Abstract Soil degradation is a critical problem in Spain, aggravated by intensive agricultural practices, urbanisation and natural phenomena such as forest fires. This study addresses soil regeneration through the valorisation of waste…

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