Failed Experiment Report
Huchegowda R, Harbishettar V, Sinha P et al. · 2025 · Preprint
Background Cognitive impairment in the older adult population has been linked to low Vitamin B12 levels and elevated Homocysteine levels, but evidence is not clear. This study examines the relationship between serum Vitamin B12 (B12)…
View details →Negative / Null Result Report
Danböck SK, Hettegger S, Franke LK et al. · 2025 · Preprint
Background: Peritraumatic dissociation is thought to contribute to posttraumatic symptoms like intrusions and memory disturbances. However, trauma-analogue studies that examined effects of experimental dissociation-induction on intrusions…
View details →Negative / Null Result Report
Ilkovska B, Trifunova BK, Ilkovski F et al. · 2025 · Preprint
Abstract Background: Breast cancer (BC) is one of the most common malignancies among women worldwide, with approximately 2.3 million new cases and 685,000 deaths reported in 2020. Inflammation-related hematologic parameters—such as the…
View details →Negative / Null Result ReportMedicine
Malmagro R, García‐Navas V, Priyadarshana TS et al. · 2025 · Global Ecology and Biogeography
AIM: Historical and contemporary environmental factors are hypothesised to influence the degree of ecological specialisation of species. Long‐term climate stability might facilitate specialisation by promoting stable environments and…
View details →Negative / Null Result ReportMedicine
Labbani-Motlagh Z, Nozarian Z, Haghi Ashtiani MT et al. · 2025 · Iranian journal of immunology : IJI
Background Coronavirus Disease 2019 (COVID-19) typically manifests with milder symptoms and lower mortality rates in children when compared to adults. Objective To investigate potential mechanisms underlying this age-related protection, we…
View details →Negative / Null Result ReportOpen accessMedicine
Bahmani A, Kemmerly T, Yang BE · 2026 · ACG case reports journal
Esophageal lichen planus (ELP) is a rare inflammatory disorder frequently misdiagnosed due to its nonspecific symptoms and overlapping features with other esophageal conditions. We present 3 cases of ELP characterized by delayed diagnosis…
View details →Negative / Null Result ReportMedicine
Komai T · 2025 · Zootaxa
A new pagurid hermit crab species, Pagurus inflatus sp. nov., has been provisionally assigned to the heterogeneous genus Pagurus Fabricius, 1775. This new species is characteristic in its elongated right cheliped with a noticeably inflated…
View details →Negative / Null Result ReportMedicine
Petrini S, Martucciello A, Righi C et al. · 2025 · Vaccine: X
Bovine alphaherpesvirus 1 (BoAHV-1) is a major cattle pathogen that causes infectious bovine rhinotracheitis (IBR) and other respiratory and reproductive disorders, resulting in substantial global economic losses to the cattle industry.…
View details →Negative / Null Result ReportMedicine
Su J, Zhang WB, Sun B et al. · 2025 · Experimental & applied acarology
Haemaphysalis flava Neumann, 1897 is recognized as a vector for Dabie bandavirus (severe fever with thrombocytopenia syndrome virus, SFTSV), which is the etiological agent of severe fever with thrombocytopenia syndrome (SFTS). The tick…
View details →Negative / Null Result ReportOpen accessMedicine
Edsor E, Jose M, Sajesh S et al. · 2025 · Journal of pharmacy & bioallied sciences
Background The aim of this study is to assess whether there is a difference in the wound healing process following the extraction of a tooth between type 2 diabetes patients on oral hypoglycemic medications and nondiabetic patients.…
View details →Failed Experiment ReportMedicine
Del Rivero J, Donahue RN, Marte JL et al. · 2025 · The oncologist
Background It has been hypothesized that sequencing antigen-directed immunotherapy with immune checkpoint inhibitors could prime a tumor for immune response to immune checkpoint inhibitors. Methods This study (NCT03072160) was designed to…
View details →Failed Experiment ReportMedicine
Andersen Z, Kilgore S, Waite-Cusic J et al. · 2025 · Journal of dairy science
Hispanic-style cheeses (HSC), particularly fresh soft varieties, have been associated with numerous outbreaks of Listeria monocytogenes, highlighting the need to identify product characteristics or interventions that could mitigate L.…
View details →Abandoned HypothesisOpen accessMedicine
Bybee SG, Clayton JL, Aruscavage N et al. · 2025 · The Gerontologist
Background and objectives Persons living with dementia often rely upon a care partner as their surrogate medical decision maker, yet little is known about how dementia care dyads achieve advance care planning (ACP) concordance: when a care…
View details →Negative / Null Result ReportMedicine
Achilles S, Tomczak JN, Baumann FS et al. · 2025 · American journal of physiology. Gastrointestinal and liver physiology
DRA (Downregulated in adenoma, SLC26A3) is a major apical intestinal Cl - /HCO 3 - exchanger, which is expressed in complex and hybrid N -glycosylated forms. Although the importance of N -glycosylation is evident from the significantly…
View details →Negative / Null Result ReportMedicine
Kostrna J, Astudillo A, Perez E · 2025 · Research quarterly for exercise and sport
Extensive research supports the positive effects of stretching on joint flexibility. During stretching, an individual's perceptions of stretch-related discomfort and pain negatively influence affective response. This study examined the…
View details →Negative / Null Result ReportOpen accessMedicine
Tian P, Fan M, Huang C · 2026 · Frontiers in medicine
Background Piperacillin-tazobactam is a widely used antibiotic. Although rare, thrombocytopenia related to piperacillin-tazobactam can be clinically significant. Drug-induced immune thrombocytopenia (DIIT) is difficult to distinguish from…
View details →Negative / Null Result ReportMedicine
Erdoğan Ş, Tavat BC · 2025 · Physiology & behavior
Previous studies have suggested that time perception fluctuates throughout the day in relation to daily fluctuations of body temperature, and that there is a negative relationship between body temperature and time perception. The aim of…
View details →Negative / Null Result Report
Necker-Brown A, Mostafa MM, Georgescu A et al. · 2025 · Preprint
Transcription factors of the interferon regulatory factor (IRF) family play key roles during viral and bacterial infections. However, IRF regulation by inflammatory cytokines, including interleukin (IL)-1β and tumor necrosis factor (TNF)…
View details →Negative / Null Result ReportMedicine
Yin CY, Vilai P, Thoreson AR et al. · 2026 · The Journal of hand surgery
Purpose Radial lengthening has been clinically proposed as an alternative treatment for distal radioulnar joint (DRUJ) instability associated with distal radius fractures based on the hypothesis that it functions in a manner similar to…
View details →Negative / Null Result Report
O’Brien C, Simon O, Franklin S et al. · 2025 · Preprint
Background: : Physical restraint of horses for veterinary procedures is necessary to allow completion of tasks effectively and without injury to patient or personnel. Objectives: : Comparison of physiological effects and behavioural…
View details →Negative / Null Result ReportMedicine
Cinque K, Deere D, Veal C et al. · 2025 · Environmental management
The major drinking water reservoirs and catchments supplying many of Australia's capital cities have been protected from significant levels of public access since their construction (up to 140 years ago). In addition to the primary…
View details →Negative / Null Result ReportMedicine
Xiong GL, Iosif AM, Gonzalez AD et al. · 2025 · Journal of the American Medical Directors Association
Objective Comparison of asynchronous telepsychiatry (ATP) with traditional synchronous telepsychiatry (STP) in skilled nursing facilities (SNFs) in California, United States. Design Patient-level randomized, controlled noninferiority…
View details →Negative / Null Result Report
Rezazadeh F, Lavaee F, Dezhkameh S et al. · 2025 · Preprint
Abstract Background: Lichen planus (LP), an inflammatory and chronic disorder, is immune-mediated and influences nails, skin, hair, and mucosal tissues. Autoimmune diseases affect females more commonly, and it is reported that there is an…
View details →Negative / Null Result Report
So R, Kariyama K, Oyamada S et al. · 2024 · Preprint
Objective To evaluate the effectiveness of screening and ultra-brief intervention (Ultra-BI) delivered by primary care physicians in less than 1 minute compared to simplified assessment only (SAO) for reducing alcohol consumption among…
View details →Negative / Null Result ReportOpen accessMedicine
Oliveira AHA, Paula DM, Serafini S et al. · 2026 · Acta cirurgica brasileira
Purpose To evaluate the effects of direct and remote ischemic preconditioning and postconditioning on kidney ischemia-reperfusion injury in young rats. Methods This study was divided into two experimental phases: preconditioning and…
View details →Negative / Null Result ReportOpen accessMedicine
Kesgin YM, Kaan AZ, Arslan M et al. · 2025 · World journal of emergency surgery : WJES
Background Textbook outcome (TO) is a concept that describes achieving an uneventful course for a patient undergoing surgery. It was first described for colorectal surgery and is now increasingly linked to various topics of surgical…
View details →Negative / Null Result ReportMedicine
Ishimaru T, Aihara I · 2025 · The Journal of experimental biology
Male cicadas emit sounds to attract females. The acoustic traits of calls vary among species and show unique patterns that dynamically change, even in the same bout. While the calling behavior of a single cicada has been quantified for…
View details →Negative / Null Result ReportMedicine
Francis AM, Anderson TJ, McKearney KJ et al. · 2025 · Psychiatry research. Neuroimaging
Cognitive impairment, particularly in attention and working memory, is a notable feature of schizophrenia (SZ). Individuals with SZ frequently consume high levels of caffeine, often exceeding 550 mg daily, yet the cognitive effects of this…
View details →Negative / Null Result ReportOpen accessMedicine
Yan J, Zheng W, Xie S et al. · 2025 · International dental journal
Introduction and aims Observational studies suggest an association between metabolic syndrome (MetS) and periodontitis. However, observational studies are susceptible to reverse causation and confounding factors, so the causality of this…
View details →Negative / Null Result Report
Zhang X, Liang S, Wang X et al. · 2025 · Preprint
Abstract Background Several special case of vitiligo patient with advanced pancreatic cancer was observed in our clinical practice, which prompted us to think about whether there is an association between the two diseases, and to further…
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