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Browse the failure-mode index

21,713 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

The Effect of PTFE Coating and PTFE Tape Wrapping Abutment Screw After Cyclic Loading: An In Vitro Study.

Kongkhuntian P, Aunmeungtong W, Khongkhunthian P · 2026 · Clinical implant dentistry and related research

Objective This study aimed to compare the effect of PTFE tape wrapping and PTFE-coated titanium alloy screws on the removal torque after cyclic loading and on preload values under repetitive tightening. Methods A total of 60 titanium…

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Negative / Null Result ReportMedicine

Reduction in copper and pesticide levels in grape musts: A new asset for the implementation of bioprotection in oenology.

Tournu E, Tourdot-Maréchal R, Coelho C · 2026 · International journal of food microbiology

Phytosanitary and copper treatments in viticulture are essential to protect vines against biotic and abiotic stresses. However, residues from these treatments can persist in grape musts and wines, potentially raising risks to consumer…

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Negative / Null Result ReportMedicine

Personalized Treatment Selection for Digital Eating Disorder Interventions: A Proof-of-Concept for the Personalized Advantage Index.

McClure Z, Fuller-Tyszkiewicz M, Messer M et al. · 2026 · The International journal of eating disorders

Objective Although a range of evidence-based treatments for eating disorders exist, treatment response varies substantially. The ability to match individuals to a treatment which they are most likely to benefit from may help improve…

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Negative / Null Result ReportMedicine

Can biochar and late-season nitrogen fertilization overcome the sulfur-containing amino acid deficiency and improve oil stability in soybean seeds?

Khatri D, Poudel S, Pun Magar L et al. · 2026 · Frontiers in plant science

Soybean meal quality for monogastric animals is limited by low sulfur-containing amino acids, especially methionine and cysteine, while oil oxidative stability is restricted by the high polyunsaturated fatty acid content. This two-year…

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Negative / Null Result ReportMedicine

A novel face scale and National Early Warning Score 2 prediction model to assess deteriorating patients in hospital wards: A quick visual early warning score study.

Wall A, Fisher JA, Watkinson EK et al. · 2026 · Australian critical care : official journal of the Confederation of Australian Critical Care Nurses

Background Early warning scores like the National Early Warning Score 2 (NEWS2) identify patient deterioration but do not incorporate clinician-intuitive assessment. Previous research suggests facial expressions can be critical indicators…

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Negative / Null Result ReportMedicine

Assessment of Seed Treatments for Management of Pathogens Causing Seed Rot, Seedling Damping-off, and Seedling Root Rot in Alfalfa ( Medicago sativa ).

Larsen LJ, Dornbusch MR, Hines-Snider C et al. · 2026 · Plant disease

Seed rot and damping-off of alfalfa ( Medicago sativa L.) is caused by a soilborne disease complex resulting in thin initial stands of plants with continuing damage during wet soil conditions decreasing forage yields and winter survival.…

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Negative / Null Result ReportMedicine

Communicating Time-to-Event Treatment Effects in Randomized Trials: A Randomized Experiment among General Practitioners.

Giese H, Gaissmaier W, Kuss O et al. · 2026 · Medical decision making : an international journal of the Society for Medical Decision Making

BackgroundTime-to-event outcomes from randomized controlled trials (RCTs) are often communicated without clearly conveying how treatment effects evolve over time. This can limit clinicians' ability to interpret results and support patient…

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Negative / Null Result ReportMedicine

Joint-specific measures improve risk adjustment in total knee arthroplasty: A machine learning approach.

Müller D, Gillani A, Hirschmann MT et al. · 2026 · Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA

Purpose Accurate risk adjustment in total knee arthroplasty (TKA) is essential for outcome prediction and quality assessment. Most existing prediction models rely solely on patient demographics and comorbidities and do not account for…

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Negative / Null Result ReportMedicine

Mortality Risk Prediction from Dense PICU Data from Patients with Suspected Infection: Data-Derived Physiological Trajectories Outperform Expert Assessments When Temporal Resolution Is High.

Velez T, Badaki-Makun O, Hirsch D et al. · 2026 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

Objective Early identification of mortality risk in critically ill children with suspected infection remains challenging. Whether severity scores (SIRS, pSOFA, Phoenix) add incremental value beyond data-derived physiologic features in…

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Negative / Null Result ReportMedicine

Is There an Added Value of Dual-Time-Point [<sup>68</sup>Ga]Ga-Fibroblast Activation Protein Inhibitor (FAPI) PET/CT in Differentiating Malignant and Benign Uptake Findings?

Al-Ibraheem A, Moghrabi S, Alsyouf B et al. · 2026 · Cancers

Background : [ 68 Ga]Ga-FAPI PET/CT demonstrates high sensitivity for tumor detection but limited specificity because benign fibro-inflammatory conditions may also show tracer uptake. Dual-time-point imaging has been proposed to improve…

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Negative / Null Result ReportMedicine

High-dose metoclopramide versus placebo for gastroduodenal visualization during endoscopy in patients with acute upper gastrointestinal bleeding. A triple-blind, randomized clinical trial.

Herrera-Elizondo JL, Jiménez-Castillo RA, García-Compeán D et al. · 2026 · Revista de gastroenterologia de Mexico (English)

Introduction and aims The usefulness of metoclopramide for improving endoscopic visualization in upper gastrointestinal bleeding (UGIB) is controversial. Our primary aim was to evaluate the utility of metoclopramide 20 mg/IV for endoscopic…

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Replication FailureMedicine

[High expression of low-risk hpv in nasal inverted papilloma and its response to interferon therapy].

He Z, Lyu S, Huang M et al. · 2026 · Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery

Objective: To investigate the expression of HPV 6/11 in NIP tissues and evaluate the adjuvant therapeutic effect of interferon-α gel on HPV-positive NIP patients. Methods: Forty-two newly diagnosed Nasal Inverted Papilloma(NIP) patients…

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Negative / Null Result ReportMedicine

Platelet-rich plasma versus plasma gel for fat graft survival under cigarette smoke exposure: An experimental study.

Naghizade B, Özyazgan İ, Bozkurt F et al. · 2026 · Journal of plastic, reconstructive & aesthetic surgery : JPRAS

Background Autologous fat grafting is widely used in plastic surgery, but graft survival remains unpredictable, particularly under compromised conditions such as cigarette smoking. Smoking impairs microcirculation and tissue oxygenation,…

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Negative / Null Result Report

Effects of Cognitive Demand Reduction on Choice Overload

Seo S, Lee S, Lee N et al. · 2026 · Preprint

Choice overload occurs when an ever-growing number of options impairs decision quality, because evaluating options taxes cognitive resources. We investigated whether reducing cognitive demand could mitigate overload by encouraging greater…

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Negative / Null Result ReportMedicine

Effect of prolonged interval between neoadjuvant chemoradiotherapy and surgery on pathological and oncological outcomes in locally advanced rectal cancer: a randomized controlled trial.

Sileika E, Cerkauskaite D, Bausys A et al. · 2026 · International journal of colorectal disease

Background The optimal interval between neoadjuvant chemoradiotherapy (nCRT) and total mesorectal excision (TME) in locally advanced rectal cancer (LARC) remains controversial. This randomized controlled trial evaluated whether prolonging…

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Negative / Null Result ReportMedicine

Digital Phenotyping and Lifestyle Intervention in Patients With Myasthenia Gravis (DIG-MG): A Randomized Controlled Trial of Feasibility, Adherence, and Effects on Fatigue.

Norling M, Eriksson N, Westerberg E et al. · 2026 · Muscle & nerve

Introduction/aims Physical activity and sleep influence fatigue in myasthenia gravis (MG), and digital health technologies (DHT) enable objective monitoring of these behaviors in daily life. Using this approach, we evaluated whether a…

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