Negative / Null Result ReportMedicine
Berube M, Bortman JM, Law AC et al. · 2026 · Hip international : the journal of clinical and experimental research on hip pathology and therapy
Background The optimal threshold to blood transfusion in patients after hip fracture surgery is unclear. This study leveraged regression discontinuity to quantify blood transfusion practices across haemoglobin thresholds of 7.0, 8.0, and…
View details →Negative / Null Result Report
Li Y, Wang D, Liu B et al. · 2026 · Preprint
Abstract Background Pulsed field ablation (PFA) is a novel non-thermal technology for atrial fibrillation (AF) ablation, but its immediate systemic effects on electrolytes remain poorly characterized. Methods We prospectively enrolled 161…
View details →Negative / Null Result ReportMedicine
Darch W, Soliman J, Higgins NC et al. · 2026 · Scientific reports
Vascular endothelial cells (VECs) play a critical role in tissue and organ homeostasis, wound healing, and immune function. VECs are commonly utilized for in vitro cell culture and in vivo tissue engineering applications which experience…
View details →Negative / Null Result ReportMedicine
Almekaty K, Alhefnawy M, Ismael A et al. · 2026 · Urology
Objective To prospectively assess the clinical outcomes and safety of microsurgical denervation of the penis (MSDP) for treatment of lifelong premature ejaculation (LPE); and to examine the impact of transitioning from partial to more…
View details →Negative / Null Result ReportMedicine
Salem AS, Albelasy NF, El-Bialy AA · 2026 · The Angle orthodontist
Objectives To compare the effectiveness of clear aligner (CA) vs removable inclined plane (RP) in improving the dentofacial changes and oral health-related quality of life (OHRQoL) in children with anterior crossbite in the mixed…
View details →Negative / Null Result ReportMedicine
Erdem Altınyürek E, Öztürk VÖ · 2026 · BMC oral health
Background Gastritis is characterized by alterations in the gastric microbiota. This dysbiosis in the stomach may affect immune system regulation as well as influence the oral microbiota. Periodontal disease results from dysbiosis of…
View details →Negative / Null Result ReportMedicine
Mamun AA · 2026 · 3 Biotech
Drought significantly alters soil microbial activity and carbon cycling, yet its effects across contrasting land-use systems remain insufficiently understood. This study investigated drought-induced changes in microbial communities and…
View details →Negative / Null Result ReportMedicine
Tuncsoy M, Tuncsoy B · 2026 · Bulletin of environmental contamination and toxicology
Aluminum (Al) is a widely occurring element in nature and is the most abundant element in the earth's crust after oxygen and silicon. In this study, metal accumulation levels in the gills, liver and muscle tissues and liver SOD, CAT and…
View details →Negative / Null Result ReportOpen accessMedicine
Nersesyan A, Kundi M, Muradyan R et al. · 2026 · Mutagenesis
We investigated the impact of cigarette smoking, daily exposure to tar and nicotine, and the duration of smoking on genetic instability (chromosomal damage-micronuclei, MN, nuclear buds-gene amplification) as well as on disturbances in…
View details →Negative / Null Result ReportMedicine
Bakir M, Sağmak S · 2026 · BMC oral health
Background This study aimed to evaluate the effects of different modeling resins on the surface roughness, surface gloss, and color stability of a nanohybrid resin composite. Methods Forty disk-shaped specimens (10 mm diameter × 2 mm…
View details →Negative / Null Result ReportMedicine
Kaplan S, de Nascimento J, Contini A · 2026 · Drug safety
Background and objectives Concerns about modafinil and armodafinil use in pregnancy emerged from animal reproductive toxicity and limited human data, including a US registry suggesting increased risk of major congenital malformations…
View details →Negative / Null Result ReportMedicine
McDonough W, Gevorkian J, Wong D et al. · 2026 · Surgical laparoscopy, endoscopy & percutaneous techniques
Background As part of the accreditation process for bariatric surgery, patients must go through a preoperative pathway. There will inevitably be patients who are seen in the clinic but never undergo surgery. This rate of attrition is…
View details →Negative / Null Result ReportOpen accessMedicine
Wakui N, Ogino Y, Nagumo H et al. · 2026 · BMC gastroenterology
Background Zinc deficiency is common in chronic liver disease and is closely associated with the progression of hepatic fibrosis and metabolic dysfunction. Although pemafibrate, a selective peroxisome proliferator-activated receptor alpha…
View details →Negative / Null Result ReportMedicine
Biedermann M, Sifakakis I, Zinelis S et al. · 2026 · European journal of oral sciences
Rubbing phosphoric acid during etching has been shown to improve surface roughness in prepared enamel. This study aimed to compare intact enamel's surface roughness and resin tag lengths after etching with and without rubbing. Extracted…
View details →Negative / Null Result ReportOpen accessMedicine
Hamid R, Bayramoğlu MN, Şirolu S et al. · 2026 · Journal of clinical medicine
Background: In this study, we radiologically assessed potential increases in microvascularity, extracellular matrix-related changes, and tissue viscoelasticity following carboxytherapy for periorbital hyperpigmentation (POH). We also…
View details →Failed Experiment ReportMedicine
Van Overmeiren T, de Alaiza Ortega SG, Calle S et al. · 2026 · Progress in cardiovascular diseases
Background Mavacamten is a cardiac myosin inhibitor used for patients with obstructive hypertrophic cardiomyopathy (oHCM). The efficacy and safety of this negative inotropic agent in oHCM and concomitant left bundle branch block (LBBB)…
View details →Failed Experiment ReportMedicine
Hernandez Lopez A, Post R, Chung J et al. · 2026 · The Permanente journal
Background Postpartum hemorrhage remains a leading cause of severe maternal morbidity and mortality. The association between mild thrombocytopenia and postpartum blood loss or red blood cell transfusion has not been well studied. Objective…
View details →Negative / Null Result ReportMedicine
Akbulut NK, Yıldız I, Yılmaz MT · 2026 · Polish journal of veterinary sciences
Melatonin not only regulates circadian rhythms in animals but also supports reproductive health through its potent antioxidant properties and immunomodulatory effects. In this study, the effects of exogenous melatonin administration on…
View details →Negative / Null Result ReportMedicine
Firoozjaei IT, Sabzi Z, Rajabloo M et al. · 2026 · Nursing research and practice
Background During pregnancy, extensive hormonal and metabolic changes can occur. Gestational diabetes can cause maternal and neonatal complications. Follow-ups have shown that women who first develop metabolic diseases during pregnancy…
View details →Negative / Null Result ReportMedicine
Şenel SSD, Çetin A · 2026 · BMC psychology
Peer bullying poses a serious risk to adolescents' psychosocial development and school adjustment. However, culturally adapted and evidence-based intervention programs remain limited in non-Western societies. Restorative justice approaches…
View details →Negative / Null Result ReportOpen accessMedicine
Ebrahimi S, Tehrani H, Ghavami V et al. · 2025 · Journal of education and health promotion
Background Brucellosis is a major bacterial infectious disease common to human beings and animals. It is considered a prevalent infection in developing countries. The present research was carried out to explore the effect of an educational…
View details →Negative / Null Result ReportOpen accessMedicine
Bilgin O, Koç M · 2026 · Behavioral sciences (Basel, Switzerland)
Solution-focused brief group counseling is a systematic approach that centers on solutions rather than the problem itself. In this approach, which focuses on the strengths of the clients, the solutions are generated by the clients…
View details →Negative / Null Result Report
Sahu SK, Nayak M, Samal A et al. · 2026 · Preprint
Abstract Hypothyroidism has been associated with cognitive disorders and high risk of neurodegenerative disorders like Alzheimer's disease (AD), which is caused by amyloid-β (Aβ) accumulation in brain. The aim of the study is to examine…
View details →Negative / Null Result ReportMedicine
Kawahata D, Biber D · 2026 · Journal of health psychology
The purpose of this study was to evaluate the impact of the Mindless to Mindful (M2M) program on fat mass, executive function, exercise identity, and exercise habit strength. A total of 89 adults consented to participate in the M2M…
View details →Negative / Null Result ReportMedicine
Chaudhry AS, Tian W, Adam TH et al. · 2026 · Aesthetic surgery journal
Background Biologic and targeted immune-modulating agents are increasingly used to manage autoimmune diseases like rheumatoid arthritis, psoriasis, and inflammatory bowel disease. As more patients receiving these therapies undergo elective…
View details →Negative / Null Result ReportOpen accessMedicine
Rahimi MR, Morton AB, Golpasandi H et al. · 2025 · BMC sports science, medicine & rehabilitation
Background Coenzyme Q10 (CoQ10), a vital mitochondrial antioxidant, may enhance cardiovascular recovery and delay fatigue in athletes. This double-blind, randomized, placebo-controlled trial investigated CoQ10's effects on cardiac stress…
View details →Negative / Null Result ReportMedicine
Karaaslan O, Türkyılmaz G, Hacıoğlu L et al. · 2026 · Biomedicines
Background/Objectives: Therapeutic plasma exchange (TPE) is an extracorporeal treatment used in thrombotic microangiopathies (TMAs) and various autoimmune and neurological disorders. However, data regarding its use during early pregnancy…
View details →Negative / Null Result ReportMedicine
Long L, Liu G, Gao G et al. · 2026 · Insects
The effects of substituting soybean meal with black soldier fly larvae (BSFL) meal on the growth performance, immunological response, intestinal morphology, and gut microbiota of Pekin ducks were assessed. A total of 150 one-day-old Pekin…
View details →Negative / Null Result ReportMedicine
Lober A, Eaton CM, Burnette S et al. · 2026 · Nursing for women's health
Objective To evaluate the impact of an evidence-based respectful maternity care program on registered nurses' attitudes and beliefs about childbirth practices across multiple U.S. hospital maternity and neonatal units. Secondary objectives…
View details →Negative / Null Result ReportMedicine
Yang F, Ma Y, Li X et al. · 2026 · Life (Basel, Switzerland)
This study aims to investigate the effects of cysteamine zinc supplementation on milk production, composition, amino acid profile, and metabolites in mares. Building on prior experimental findings, a dose of 7 mg/kg body weight of CS-Zn…
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