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Browse the failure-mode index

21,283 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Barriers, facilitators and promising interventions for reducing sedentary behaviour during and after stroke rehabilitation - A scoping review.

Te Lindert L, van Meijeren-Pont W, Meesters J et al. · 2026 · Disability and rehabilitation

Purpose Reducing sedentary behaviour (SB) in stroke rehabilitation is essential, yet effects of most interventions remain limited. This review used the Behaviour Change Wheel to identify: (1) barriers and facilitators for reducing SB of…

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Negative / Null Result ReportMedicine

SlROP4 negatively regulates drought tolerance in tomato.

Cheng C, Li M, Sun B et al. · 2026 · Plant science : an international journal of experimental plant biology

Rho-like GTPases of plants (ROPs) regulate diverse cellular processes, but their roles in tomato drought responses are largely unknown. In this study, nine ROP genes were identified in tomato (Solanum lycopersicum). Among them, SlROP4, the…

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Negative / Null Result ReportOpen accessMedicine

Effects of Phenolic-Rich Extra Virgin Olive Oil and Prebiotics on Sarcopenia in Older Adults: FOOP-Sarc Project.

Besora-Moreno M, Jiménez-Ten Hoevel C, Queral J et al. · 2026 · Journal of cachexia, sarcopenia and muscle

Background Management of sarcopenia by nutritional and lifestyle interventions is a challenge. The aim is to assess the effectiveness of a phenolic-rich extra virgin olive oil (EVOO), alone or combined with a prebiotic (PREB)…

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Negative / Null Result Report

Geriatric dentistry in brazilian dental education

Moimaz SAS, Dias GZT, Martins RJ et al. · 2026 · Preprint

Abstract Introduction: The increase in life expectancy in Brazil has led to significant changes in the population pyramid. Considering the different stages of life and the specific oral health conditions associated with older adults,…

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Negative / Null Result ReportOpen accessMedicine

Lumbar Plexus Block

Yao PY, Hendrix JM · 2026

The concept of a regional anesthesia technique that provides neural blockade of the entire lumbar plexus, a lumbar plexus block, dates back nearly 50 years. The first description of such a block by Winnie et al in 1973 was an “inguinal…

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Negative / Null Result ReportOpen accessMedicine

Features and trends of marine heat waves and marine cold spells along the Western Iberian Coast from four decades of satellite data.

Biguino B, Haigh ID, Dias JM et al. · 2025 · Scientific reports

Marine Heat Waves (MHWs) have been the focus of numerous studies due to the dramatic consequences they can have on coastal systems. However, Marine Cold Spells (MCSs) can also have harmful effects on the environment while play an important…

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Negative / Null Result ReportMedicine

Inclusion of high-pressure-treated grape pomace to modulate barbecued Frankfurter sausages: insights into oxidation and PAH generation during barbecuing.

Andrés AI, Martín-Mateos MJ, D'Arrigo M et al. · 2026 · Food chemistry

This study evaluated the effects of high hydrostatic pressure (HHP)-treated white (WGP) and red grape pomace (RGP) on oxidative stability, volatile compounds, and polycyclic aromatic hydrocarbons (PAHs) in barbecued Frankfurter sausages.…

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Negative / Null Result ReportOpen accessMedicine

Investigating cycle-to-cycle variation and the impact of endometrial injury through differential gene expression analysis.

Teh WT, Chung J, Donoghue JF et al. · 2026 · Human reproduction (Oxford, England)

Study question Does endometrial gene expression change across consecutive cycles and after endometrial injury? Summary answer Although paired endometrial samples collected from the same woman across two consecutive cycles show greater…

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Negative / Null Result ReportMedicine

Effect of Tai Chi vs. Strength Training on Body Composition, Physical Performance, and Well-Being in Community-Dwelling Older Mexican Women.

Flores-Bello C, Correa-Muñoz E, Sánchez-Rodríguez MA et al. · 2026 · Healthcare (Basel, Switzerland)

Background/Objectives : Tai Chi (TC) practice has been shown to positively affect the physical, psychological, and cognitive health of older adults. However, discrepancies persist regarding its effectiveness compared to strength training…

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Negative / Null Result ReportMedicine

Pharmacokinetics, pharmacodynamics, and radiomitigative efficacy of IEPA in a non-human primate model of acute radiation syndrome.

Wesolowski R, Asang C, Eibl M et al. · 2026 · International journal of radiation biology

Purpose The acute radiation syndrome (ARS) represents a significant public health threat following nuclear exposure, with limited available medical countermeasures (MCMs). Imidazolyl ethanamide pentandioic acid (IEPA), a novel orally…

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Negative / Null Result ReportMedicine

[Translated article] Is one year follow-up sufficient to assess functional outcomes after rotator cuff repair?

Pasqualini I, Lucero Viviani N, Turan O et al. · 2026 · Revista espanola de cirugia ortopedica y traumatologia

Background Arthroscopic rotator cuff repair (ARCR) traditionally requires a 2-year follow-up to report results. However, most of the recovery occurs within the first year. The aim of this study was to determine if there are clinically…

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Negative / Null Result Report

Acceptability, Implementation Fidelity, and Preliminary Psychological Outcomes of a DBT- Informed Emotional Skills Program in a Secondary School: A Pre–Post Study Among Adolescents in Chile

Gaete J, Romo V, Contreras C et al. · 2026 · Preprint

Abstract Background School-based interventions grounded in evidence-based psychological approaches are increasingly used to promote adolescent mental health. Dialectical Behavior Therapy (DBT) skills training has shown promise; however,…

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Negative / Null Result ReportOpen accessMedicine

IL-18 and MIG increase one year after transition to dolutegravir-based dual therapy despite sustained viral suppression.

Pérez-González A, Alonso-Domínguez J, Martínez-Barros I et al. · 2026 · Frontiers in immunology

Introduction Modern antiretroviral treatment allowed a significant improvement in the life expectancy of people with HIV (PWH), exhibiting robust and sustained efficacy with scarce toxicities, both in two-drug regimens (2DRs) and…

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Negative / Null Result ReportMedicine

Condylar Positional Changes Following Manual Proximal Segment Positioning During Bilateral Sagittal Split Ramus Osteotomy: A Cephalometric Study.

Tanrısever NC, Gökalp H · 2026 · Medicina (Kaunas, Lithuania)

Background and Objectives : Maintenance of condylar position during bilateral sagittal split ramus osteotomy (BSSRO) is important for preserving temporomandibular joint biomechanics and skeletal stability. During surgery, loss of muscle…

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Negative / Null Result ReportMedicine

Efficacy of nonablative radiofrequency on sexual function in postmenopausal women: a randomized clinical trial.

Quezada-Bascuñán C, Ferri-Morales A, Martínez-Vizcaíno V et al. · 2026 · Menopause (New York, N.Y.)

Objective To evaluate the efficacy of nonablative capacitive-resistive monopolar radiofrequency on sexual function and vaginal health in postmenopausal women with genitourinary syndrome of menopause. Methods This was a single-blind,…

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Negative / Null Result ReportOpen accessMedicine

Effect of <i>Bacillus coagulans</i> DSM 32016 (TechnoSpore<sup>®</sup>) Supplementation on Growth Performance and Selected Blood Parameters and Serum Urea in Weaning Danube White Pigs.

Eneva K, Yordanova G, Petrova M et al. · 2026 · Life (Basel, Switzerland)

The present study evaluated the effects of dietary supplementation with Bacillus coagulans DSM 32016 on growth performance, hematological and biochemical parameters, and nitrogen metabolism in weaned Danube White pigs reared under standard…

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Failed Experiment ReportOpen accessMedicine

Probiotics alleviate oral microbiota disruptions induced by <i>Helicobacter pylori</i> eradication with vonoprazan-amoxicillin dual therapy: a randomized double-blind placebo-controlled trial. (An exploratory study).

Wei W, Chen W, Peng R et al. · 2026 · Frontiers in cellular and infection microbiology

Background Helicobacter pylori ( H. pylori ) infection affects approximately half of the global population and has been linked to oral microbiota dysbiosis, while eradication therapies may further disrupt microbial balance. This…

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